DE60024664T2 - Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren - Google Patents

Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren Download PDF

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Publication number
DE60024664T2
DE60024664T2 DE60024664T DE60024664T DE60024664T2 DE 60024664 T2 DE60024664 T2 DE 60024664T2 DE 60024664 T DE60024664 T DE 60024664T DE 60024664 T DE60024664 T DE 60024664T DE 60024664 T2 DE60024664 T2 DE 60024664T2
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DE
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Prior art keywords
peptide
plmf
sequence
amino acids
downstream
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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DE60024664T
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German (de)
English (en)
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DE60024664D1 (de
Inventor
P. Terrance SNUTCH
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University of British Columbia
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University of British Columbia
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Publication of DE60024664T2 publication Critical patent/DE60024664T2/de
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Expired - Fee Related legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70571Assays involving receptors, cell surface antigens or cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60024664T 1999-10-13 2000-10-13 Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren Expired - Fee Related DE60024664T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15909599P 1999-10-13 1999-10-13
US159095P 1999-10-13
PCT/CA2000/001233 WO2001027630A2 (en) 1999-10-13 2000-10-13 Methods to identify compounds that modulate neuronal activity

Publications (2)

Publication Number Publication Date
DE60024664D1 DE60024664D1 (de) 2006-01-12
DE60024664T2 true DE60024664T2 (de) 2006-07-06

Family

ID=22571069

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60024664T Expired - Fee Related DE60024664T2 (de) 1999-10-13 2000-10-13 Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren

Country Status (9)

Country Link
US (1) US6531288B1 (enExample)
EP (1) EP1230551B1 (enExample)
JP (1) JP2003511087A (enExample)
AT (1) ATE312350T1 (enExample)
AU (1) AU7896700A (enExample)
CA (1) CA2385907A1 (enExample)
DE (1) DE60024664T2 (enExample)
ES (1) ES2253263T3 (enExample)
WO (1) WO2001027630A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2424269T3 (es) * 2002-11-01 2013-09-30 Iris International, Inc. Inmuno-PCR sándwich por desplazamiento
US20050266524A1 (en) * 2003-12-03 2005-12-01 Bulla Lee A Beta integrin gene and protein
JP5188808B2 (ja) * 2004-11-03 2013-04-24 アイリス モレキュラー ダイアグノスティクス, インコーポレイテッド 同種の分析物検出
PT1815028E (pt) * 2004-11-03 2012-01-24 Iris Molecular Diagnostics Inc Microbolhas para separação por afinidade
US20090246781A1 (en) * 2008-02-21 2009-10-01 Robert Klem Method for early determination of recurrence after therapy for prostate cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874236A (en) 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US5623051A (en) * 1994-11-10 1997-04-22 University Of Washington Methods and compositions for screening for presynaptic calcium channel blockers
JPH09299092A (ja) * 1996-03-12 1997-11-25 Takeda Chem Ind Ltd 新規タンパク質およびそのdna

Also Published As

Publication number Publication date
JP2003511087A (ja) 2003-03-25
WO2001027630A3 (en) 2001-12-06
ES2253263T3 (es) 2006-06-01
ATE312350T1 (de) 2005-12-15
AU7896700A (en) 2001-04-23
CA2385907A1 (en) 2001-04-19
US6531288B1 (en) 2003-03-11
WO2001027630A2 (en) 2001-04-19
EP1230551A2 (en) 2002-08-14
EP1230551B1 (en) 2005-12-07
DE60024664D1 (de) 2006-01-12

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