ATE312350T1 - Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren - Google Patents
Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulierenInfo
- Publication number
- ATE312350T1 ATE312350T1 AT00969145T AT00969145T ATE312350T1 AT E312350 T1 ATE312350 T1 AT E312350T1 AT 00969145 T AT00969145 T AT 00969145T AT 00969145 T AT00969145 T AT 00969145T AT E312350 T1 ATE312350 T1 AT E312350T1
- Authority
- AT
- Austria
- Prior art keywords
- neuronal activity
- modulate neuronal
- identifying connections
- modulate
- type
- Prior art date
Links
- 230000001537 neural effect Effects 0.000 title 1
- 108090000312 Calcium Channels Proteins 0.000 abstract 1
- 102000003922 Calcium Channels Human genes 0.000 abstract 1
- 102000010029 Homer Scaffolding Proteins Human genes 0.000 abstract 1
- 108010077223 Homer Scaffolding Proteins Proteins 0.000 abstract 1
- 108090000862 Ion Channels Proteins 0.000 abstract 1
- 102000004310 Ion Channels Human genes 0.000 abstract 1
- 102000013265 Syntaxin 1 Human genes 0.000 abstract 1
- 108010090618 Syntaxin 1 Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70571—Assays involving receptors, cell surface antigens or cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15909599P | 1999-10-13 | 1999-10-13 | |
| PCT/CA2000/001233 WO2001027630A2 (en) | 1999-10-13 | 2000-10-13 | Methods to identify compounds that modulate neuronal activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312350T1 true ATE312350T1 (de) | 2005-12-15 |
Family
ID=22571069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00969145T ATE312350T1 (de) | 1999-10-13 | 2000-10-13 | Verfahren zur identifizierung von verbindungen, die die neuronale aktivität modulieren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6531288B1 (enExample) |
| EP (1) | EP1230551B1 (enExample) |
| JP (1) | JP2003511087A (enExample) |
| AT (1) | ATE312350T1 (enExample) |
| AU (1) | AU7896700A (enExample) |
| CA (1) | CA2385907A1 (enExample) |
| DE (1) | DE60024664T2 (enExample) |
| ES (1) | ES2253263T3 (enExample) |
| WO (1) | WO2001027630A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2424269T3 (es) * | 2002-11-01 | 2013-09-30 | Iris International, Inc. | Inmuno-PCR sándwich por desplazamiento |
| US20050266524A1 (en) * | 2003-12-03 | 2005-12-01 | Bulla Lee A | Beta integrin gene and protein |
| JP5188808B2 (ja) * | 2004-11-03 | 2013-04-24 | アイリス モレキュラー ダイアグノスティクス， インコーポレイテッド | 同種の分析物検出 |
| PT1815028E (pt) * | 2004-11-03 | 2012-01-24 | Iris Molecular Diagnostics Inc | Microbolhas para separação por afinidade |
| US20090246781A1 (en) * | 2008-02-21 | 2009-10-01 | Robert Klem | Method for early determination of recurrence after therapy for prostate cancer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874236A (en) | 1988-04-04 | 1999-02-23 | Sibia Neurosciences. Inc. | DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits |
| US5623051A (en) * | 1994-11-10 | 1997-04-22 | University Of Washington | Methods and compositions for screening for presynaptic calcium channel blockers |
| JPH09299092A (ja) * | 1996-03-12 | 1997-11-25 | Takeda Chem Ind Ltd | 新規タンパク質およびそのｄｎａ |
-
2000
- 2000-10-13 CA CA002385907A patent/CA2385907A1/en not_active Abandoned
- 2000-10-13 ES ES00969145T patent/ES2253263T3/es not_active Expired - Lifetime
- 2000-10-13 AU AU78967/00A patent/AU7896700A/en not_active Abandoned
- 2000-10-13 JP JP2001530589A patent/JP2003511087A/ja active Pending
- 2000-10-13 WO PCT/CA2000/001233 patent/WO2001027630A2/en not_active Ceased
- 2000-10-13 US US09/688,295 patent/US6531288B1/en not_active Expired - Fee Related
- 2000-10-13 EP EP00969145A patent/EP1230551B1/en not_active Expired - Lifetime
- 2000-10-13 AT AT00969145T patent/ATE312350T1/de not_active IP Right Cessation
- 2000-10-13 DE DE60024664T patent/DE60024664T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003511087A (ja) | 2003-03-25 |
| WO2001027630A3 (en) | 2001-12-06 |
| ES2253263T3 (es) | 2006-06-01 |
| AU7896700A (en) | 2001-04-23 |
| CA2385907A1 (en) | 2001-04-19 |
| US6531288B1 (en) | 2003-03-11 |
| WO2001027630A2 (en) | 2001-04-19 |
| DE60024664T2 (de) | 2006-07-06 |
| EP1230551A2 (en) | 2002-08-14 |
| EP1230551B1 (en) | 2005-12-07 |
| DE60024664D1 (de) | 2006-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |