CA2385907A1 - Methods to identify compounds that modulate neuronal activity - Google Patents

Methods to identify compounds that modulate neuronal activity Download PDF

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Publication number
CA2385907A1
CA2385907A1 CA002385907A CA2385907A CA2385907A1 CA 2385907 A1 CA2385907 A1 CA 2385907A1 CA 002385907 A CA002385907 A CA 002385907A CA 2385907 A CA2385907 A CA 2385907A CA 2385907 A1 CA2385907 A1 CA 2385907A1
Authority
CA
Canada
Prior art keywords
peptide
sequence
plmf
carboxy terminus
ion channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002385907A
Other languages
English (en)
French (fr)
Inventor
Terrance P. Snutch
John Mcrory
Kathy G. Sutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2385907A1 publication Critical patent/CA2385907A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70571Assays involving receptors, cell surface antigens or cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002385907A 1999-10-13 2000-10-13 Methods to identify compounds that modulate neuronal activity Abandoned CA2385907A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15909599P 1999-10-13 1999-10-13
US60/159,095 1999-10-13
PCT/CA2000/001233 WO2001027630A2 (en) 1999-10-13 2000-10-13 Methods to identify compounds that modulate neuronal activity

Publications (1)

Publication Number Publication Date
CA2385907A1 true CA2385907A1 (en) 2001-04-19

Family

ID=22571069

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002385907A Abandoned CA2385907A1 (en) 1999-10-13 2000-10-13 Methods to identify compounds that modulate neuronal activity

Country Status (9)

Country Link
US (1) US6531288B1 (enExample)
EP (1) EP1230551B1 (enExample)
JP (1) JP2003511087A (enExample)
AT (1) ATE312350T1 (enExample)
AU (1) AU7896700A (enExample)
CA (1) CA2385907A1 (enExample)
DE (1) DE60024664T2 (enExample)
ES (1) ES2253263T3 (enExample)
WO (1) WO2001027630A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2424269T3 (es) * 2002-11-01 2013-09-30 Iris International, Inc. Inmuno-PCR sándwich por desplazamiento
US20050266524A1 (en) * 2003-12-03 2005-12-01 Bulla Lee A Beta integrin gene and protein
JP5188808B2 (ja) * 2004-11-03 2013-04-24 アイリス モレキュラー ダイアグノスティクス, インコーポレイテッド 同種の分析物検出
PT1815028E (pt) * 2004-11-03 2012-01-24 Iris Molecular Diagnostics Inc Microbolhas para separação por afinidade
US20090246781A1 (en) * 2008-02-21 2009-10-01 Robert Klem Method for early determination of recurrence after therapy for prostate cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874236A (en) 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US5623051A (en) * 1994-11-10 1997-04-22 University Of Washington Methods and compositions for screening for presynaptic calcium channel blockers
JPH09299092A (ja) * 1996-03-12 1997-11-25 Takeda Chem Ind Ltd 新規タンパク質およびそのdna

Also Published As

Publication number Publication date
JP2003511087A (ja) 2003-03-25
WO2001027630A3 (en) 2001-12-06
ES2253263T3 (es) 2006-06-01
ATE312350T1 (de) 2005-12-15
AU7896700A (en) 2001-04-23
US6531288B1 (en) 2003-03-11
WO2001027630A2 (en) 2001-04-19
DE60024664T2 (de) 2006-07-06
EP1230551A2 (en) 2002-08-14
EP1230551B1 (en) 2005-12-07
DE60024664D1 (de) 2006-01-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued