DE60023189D1 - Herstellung und reinigung von cyclosporin-a - Google Patents

Herstellung und reinigung von cyclosporin-a

Info

Publication number
DE60023189D1
DE60023189D1 DE60023189T DE60023189T DE60023189D1 DE 60023189 D1 DE60023189 D1 DE 60023189D1 DE 60023189 T DE60023189 T DE 60023189T DE 60023189 T DE60023189 T DE 60023189T DE 60023189 D1 DE60023189 D1 DE 60023189D1
Authority
DE
Germany
Prior art keywords
cyclosporin
cleaning
preparation
alum
extracted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023189T
Other languages
English (en)
Inventor
Anand Prakash Khedkar
Pampapathy Subramaniyam
Konayakanahalli Nanjunda Anand
Melarkode Ramkrishna
Shreehas Pradeep Tambe
Sambasivam Ganesh
Anindya Sircar
Shrikumar Suryanarayan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocon Ltd
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Application granted granted Critical
Publication of DE60023189D1 publication Critical patent/DE60023189D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
DE60023189T 2000-02-29 2000-02-29 Herstellung und reinigung von cyclosporin-a Expired - Lifetime DE60023189D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2000/000018 WO2001064935A1 (en) 2000-02-29 2000-02-29 Manufacture and purification of cyclosporin a

Publications (1)

Publication Number Publication Date
DE60023189D1 true DE60023189D1 (de) 2006-02-23

Family

ID=11076228

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023189T Expired - Lifetime DE60023189D1 (de) 2000-02-29 2000-02-29 Herstellung und reinigung von cyclosporin-a

Country Status (7)

Country Link
US (1) US7176001B1 (de)
EP (1) EP1261732B1 (de)
AT (1) ATE306558T1 (de)
AU (1) AU2000235743A1 (de)
CA (1) CA2401700A1 (de)
DE (1) DE60023189D1 (de)
WO (1) WO2001064935A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1763084B (zh) * 2005-10-11 2010-04-21 山东新时代药业有限公司 高纯度环孢菌素a的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904476A (en) * 1973-05-29 1975-09-09 Mobil Oil Corp Treatment of cells of a hydrocarbon-consuming microorganism
US4117118A (en) 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
SE448386B (sv) * 1978-10-18 1987-02-16 Sandoz Ag Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
US4466885A (en) * 1982-07-13 1984-08-21 Husky Oil Operations Ltd. Method for removing solids and water from petroleum crudes
US4569793A (en) * 1984-09-26 1986-02-11 Shell Oil Company Cyanohydrination catalyst
US4762923A (en) * 1986-11-21 1988-08-09 Merck & Co. Inc. Fermentation analogs of virginiamycin M1
US4843054A (en) * 1987-02-26 1989-06-27 Arco Chemical Technology, Inc. Preparation of filterable double metal cyanide complex catalyst for propylene oxide polymerization
HU201577B (en) 1988-12-20 1990-11-28 Gyogyszerkutato Intezet Process for producing cyclosporin antibiotics
EP0507968B1 (de) * 1991-04-06 1995-09-06 Arzneimittelwerk Dresden Gmbh Verfahren zur fermentativen Herstellung und Isolierung von Cyclosporin A sowie neue Cyclosporin- bildende Stämme
FI92334C (fi) * 1992-12-30 1994-10-25 Leiras Oy Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
CA2108655A1 (en) 1993-10-18 1995-04-19 Argyrios Margaritis Supercritical co2 extraction of cyclosporin a
KR0126610B1 (ko) 1994-10-18 1997-12-29 김충환 고생산 세포융합변이균주에 의한 사이클로스포린 a의 제조방법
EP0725076B1 (de) * 1995-02-01 2001-06-06 National Research Development Corporation of India Verfahren zur Gewinnung von Cyclosporin A aus einer Tolypocladiumspecies
US5747330A (en) 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
EP0913097B1 (de) * 1997-10-31 2005-01-12 Societe Des Produits Nestle S.A. Herstellung eines Hydrolysates
US6197573B1 (en) * 1998-11-17 2001-03-06 Biocon India Limited Solid state fermentation

Also Published As

Publication number Publication date
WO2001064935A1 (en) 2001-09-07
CA2401700A1 (en) 2001-09-07
ATE306558T1 (de) 2005-10-15
US7176001B1 (en) 2007-02-13
AU2000235743A1 (en) 2001-09-12
EP1261732A1 (de) 2002-12-04
EP1261732B1 (de) 2005-10-12

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