DE60010500D1 - Verbundnanopartikel sowie deren konjugate mit biomolekülen - Google Patents

Verbundnanopartikel sowie deren konjugate mit biomolekülen

Info

Publication number
DE60010500D1
DE60010500D1 DE60010500T DE60010500T DE60010500D1 DE 60010500 D1 DE60010500 D1 DE 60010500D1 DE 60010500 T DE60010500 T DE 60010500T DE 60010500 T DE60010500 T DE 60010500T DE 60010500 D1 DE60010500 D1 DE 60010500D1
Authority
DE
Germany
Prior art keywords
minus
plus
conjugates
biomolecules
organic phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60010500T
Other languages
English (en)
Other versions
DE60010500T2 (de
Inventor
Abdelhamid Elaissari
Eric Bosc
Christian Pichot
Bernard Mandrand
Jerome Bibette
Olivier Mondain-Monval
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Centre National de la Recherche Scientifique CNRS
Original Assignee
Biomerieux SA
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA, Centre National de la Recherche Scientifique CNRS filed Critical Biomerieux SA
Application granted granted Critical
Publication of DE60010500D1 publication Critical patent/DE60010500D1/de
Publication of DE60010500T2 publication Critical patent/DE60010500T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/60—Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/64—Magnetic material dispersed in oil drop
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/60—Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/66—Magnetic material dispersed in surfactant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y10T428/2987—Addition polymer from unsaturated monomers only
DE60010500T 1999-11-05 2000-11-06 Verbundnanopartikel sowie deren konjugate mit biomolekülen Expired - Lifetime DE60010500T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9914194 1999-11-05
FR9914194A FR2800635B1 (fr) 1999-11-05 1999-11-05 Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
PCT/FR2000/003085 WO2001033223A1 (fr) 1999-11-05 2000-11-06 Nanospheres composites et leurs conjugues avec des biomolecules

Publications (2)

Publication Number Publication Date
DE60010500D1 true DE60010500D1 (de) 2004-06-09
DE60010500T2 DE60010500T2 (de) 2005-05-12

Family

ID=9552017

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010500T Expired - Lifetime DE60010500T2 (de) 1999-11-05 2000-11-06 Verbundnanopartikel sowie deren konjugate mit biomolekülen

Country Status (10)

Country Link
US (2) US6866838B1 (de)
EP (1) EP1226438B1 (de)
JP (2) JP4980532B2 (de)
AT (1) ATE266201T1 (de)
AU (1) AU1288201A (de)
CA (1) CA2390077A1 (de)
DE (1) DE60010500T2 (de)
ES (1) ES2220560T3 (de)
FR (1) FR2800635B1 (de)
WO (1) WO2001033223A1 (de)

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FR2804117B1 (fr) * 2000-01-21 2004-08-20 Bio Merieux Procede d'isolement de proteines et/ou d'acides nucleiques, complexes de particules et de proteines et/ou d'acides nucleiques, reactif et applications
JP2003535063A (ja) 2000-06-01 2003-11-25 ザ・ボード・オブ・リージェンツ・フォー・オクラホマ・ステート・ユニバーシティー 放射線医薬としてのナノ粒子のバイオコンジュゲート
FR2824563B1 (fr) * 2001-05-10 2004-12-03 Bio Merieux Particules composites, conjugues derives, procede de preparation et applications
EP1306128A1 (de) * 2001-10-29 2003-05-02 Tenaxis Gmbh Sorptionsfähige Kompositmaterialen
US7939170B2 (en) 2002-08-15 2011-05-10 The Rockefeller University Water soluble metal and semiconductor nanoparticle complexes
JP2004175922A (ja) * 2002-11-27 2004-06-24 Toppan Forms Co Ltd ヌクレオチド重合体マイクロカプセルインキ
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CN1312479C (zh) 2003-08-08 2007-04-25 清华大学 一种纳米荧光磁粒及其制备方法
FR2860717B1 (fr) * 2003-10-13 2006-02-03 Ethypharm Sa Compositions de particules lipidiques solides monodisperses
CA2553647A1 (en) * 2004-01-20 2005-08-04 Alnis Biosciences, Inc. Articles comprising magnetic material and bioactive agents
US7964380B2 (en) * 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
EP1721603A1 (de) * 2005-05-11 2006-11-15 Albert-Ludwigs-Universität Freiburg Nanopartikel geeignet für Biokonjugation
CA2615939A1 (en) * 2005-08-02 2007-02-08 Miv Therapeutics Inc. Microdevices comprising nanocapsules for controlled delivery of drugs and method of manufacturing same
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USH2257H1 (en) * 2005-09-28 2011-06-07 The United States Of America As Represented By The Secretary Of The Navy Microtags for detection and identification of materials
DE102005047786A1 (de) * 2005-10-05 2007-04-19 Urs Isler Verfahren zur Behandlung von Gamen zur Authentifizierung und Vorrichtung zum Nachweis der Authentizität
DK1945271T3 (da) * 2005-10-24 2020-01-13 Magsense Life Sciences Inc Fremgangsmåde til fremstilling af polymerbelagte mikropartikler
FR2894970B1 (fr) * 2005-12-15 2008-01-25 Biomerieux Sa Procede de preparation de particules composites, particules composites obtenues et leur utilisation dans un test diagnostic
EP2000484B1 (de) 2006-03-27 2011-11-30 Tokyo Institute of Technology Verfahren zur herstellung von polymerbeschichtetem ferromagnetischem teilchen und polymerbeschichtetes ferromagnetisches teilchen
EP2084550A1 (de) * 2006-11-08 2009-08-05 T2 Biosystems, Inc. Nmr-system für den in-vivo-nachweis von analyten
US7981688B2 (en) * 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
KR100860506B1 (ko) 2007-08-28 2008-09-26 연세대학교 산학협력단 금속 나노입자를 포함하는 고분자 복합재 및 그의 합성방법
CA2700970A1 (en) 2007-09-28 2009-04-09 T2 Biosystems, Inc. Nmr diagnostics by means of a plastic sample container
US8519708B2 (en) * 2007-11-06 2013-08-27 T2 Biosystems, Inc. Small magnet and RF coil for magnetic resonance relaxometry
WO2010005741A1 (en) * 2008-06-16 2010-01-14 Georgia Tech Research Corporation Nanogels for cellular delivery of therapeutics
WO2010035258A2 (en) * 2008-09-25 2010-04-01 Nanoready Ltd. Discrete metallic copper nanoparticles
JP5926958B2 (ja) 2008-10-29 2016-05-25 ティー２ バイオシステムズ，インコーポレーテッド 凝固時間のｎｍｒ検出
ES2491615T3 (es) 2009-02-12 2014-09-08 Bayer Intellectual Property Gmbh Recubrimientos antireflexión / antiempañamiento
US8689981B2 (en) 2009-04-10 2014-04-08 President And Fellows Of Harvard College Manipulation of particles in channels
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US9523701B2 (en) 2009-07-29 2016-12-20 Dynex Technologies, Inc. Sample plate systems and methods
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US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
BR112012011248A2 (pt) 2009-11-11 2016-04-05 Basf Se processo para separar pelo menos um primeiro material de uma mistura
ES2576927T3 (es) 2010-10-22 2016-07-12 T2 Biosystems, Inc. Sistemas de RMN y métodos para la detección rápida de analitos
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
CN103917658B (zh) 2011-07-13 2016-09-21 T2生物系统公司 用于监测血块形成的nmr方法
EP2752239A4 (de) * 2011-08-31 2015-08-12 Shanghai World Prospect Chemtech Co Ltd Anorganischer nichtmetallischer mineralverbundstoff mit titandioxidschicht und herstellungsverfahren dafür
EP2748651B1 (de) 2011-09-21 2017-08-30 T2 Biosystems, Inc. Nmr-verfahren für endotoxinanalyse
WO2013158281A1 (en) 2012-04-20 2013-10-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
KR101382530B1 (ko) * 2012-06-07 2014-04-07 한양대학교 에리카산학협력단 팔라듐이 담지된 유기화학 반응 촉매 및 이를 이용하여 바이아릴 화합물을 제조하는 방법
JP2016500443A (ja) 2012-12-07 2016-01-12 ティー２ バイオシステムズ，インコーポレーテッド 強固な血餅形成をモニタリングするための方法
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CN111589387A (zh) * 2020-04-21 2020-08-28 同济大学 一种微胶囊复合材料及其制备方法
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Also Published As

Publication number Publication date
US7001589B2 (en) 2006-02-21
CA2390077A1 (fr) 2001-05-10
ES2220560T3 (es) 2004-12-16
JP2012017332A (ja) 2012-01-26
AU1288201A (en) 2001-05-14
ATE266201T1 (de) 2004-05-15
JP4980532B2 (ja) 2012-07-18
FR2800635B1 (fr) 2002-07-26
DE60010500T2 (de) 2005-05-12
EP1226438A1 (de) 2002-07-31
US20050137334A1 (en) 2005-06-23
WO2001033223A1 (fr) 2001-05-10
FR2800635A1 (fr) 2001-05-11
JP2003513093A (ja) 2003-04-08
EP1226438B1 (de) 2004-05-06
US6866838B1 (en) 2005-03-15

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