DE60004432D1 - Verfahren zur Herstellung von Hydroxamsäuren - Google Patents

Verfahren zur Herstellung von Hydroxamsäuren

Info

Publication number
DE60004432D1
DE60004432D1 DE60004432T DE60004432T DE60004432D1 DE 60004432 D1 DE60004432 D1 DE 60004432D1 DE 60004432 T DE60004432 T DE 60004432T DE 60004432 T DE60004432 T DE 60004432T DE 60004432 D1 DE60004432 D1 DE 60004432D1
Authority
DE
Germany
Prior art keywords
preparation
hydroxamic acids
carboxylic acid
hydroxycarbamoyl
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60004432T
Other languages
English (en)
Other versions
DE60004432T2 (de
Inventor
Florian Staebler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60004432D1 publication Critical patent/DE60004432D1/de
Application granted granted Critical
Publication of DE60004432T2 publication Critical patent/DE60004432T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60004432T 1999-05-11 2000-05-05 Verfahren zur Herstellung von Hydroxamsäuren Expired - Fee Related DE60004432T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99109431 1999-05-11
EP99109431 1999-05-11

Publications (2)

Publication Number Publication Date
DE60004432D1 true DE60004432D1 (de) 2003-09-18
DE60004432T2 DE60004432T2 (de) 2004-06-24

Family

ID=8238160

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60004432T Expired - Fee Related DE60004432T2 (de) 1999-05-11 2000-05-05 Verfahren zur Herstellung von Hydroxamsäuren

Country Status (11)

Country Link
US (1) US6452010B1 (de)
EP (1) EP1052249B1 (de)
JP (1) JP3382208B2 (de)
KR (1) KR100377695B1 (de)
CN (1) CN1156453C (de)
AT (1) ATE247084T1 (de)
CA (1) CA2307994A1 (de)
DE (1) DE60004432T2 (de)
DK (1) DK1052249T3 (de)
ES (1) ES2203370T3 (de)
JO (1) JO2258B1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107032992A (zh) * 2017-04-05 2017-08-11 华东师范大学 一种(r)‑4‑(叔丁氧基)‑2‑(环戊基甲基)‑4‑氧代丁酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2483252A (en) 1945-04-20 1949-09-27 Commercial Solvents Corp Method for preparing hydroxylammonium salts of organic acids
EP0108294B1 (de) * 1982-11-01 1991-02-06 AlliedSignal Inc. Herstellung von alkoholischen Hydroxylaminlösungen aus Hydroxylammoniumsulfat, von Oximen, Hydroxamsäuren und von anderen Hydroxylammoniumsalzen mittels alkoholischer Hydroxylaminlösungen
DE3601216A1 (de) * 1986-01-17 1987-07-23 Basf Ag Verfahren zur herstellung von reinen hydroxylammoniumsalzen von fettsaeuren mit 1 bis 4 kohlenstoffatomen
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
CA2147590C (en) * 1994-04-22 2002-02-19 Mitsui Chemicals, Inc. A process for producing substituted amines and a method for purifying synthetic intermediates therefor
GB9501737D0 (en) * 1994-04-25 1995-03-22 Hoffmann La Roche Hydroxamic acid derivatives
JP3382127B2 (ja) 1996-07-04 2003-03-04 エフ．ホフマン−ラ ロシュ アーゲー キラルなコハク酸誘導体の製造方法
EP0818442A3 (de) 1996-07-12 1998-12-30 Pfizer Inc. Cyclische Sulphonderivate als Metalloproteinase-Inhibitoren und zur Hemmung der Produktion von Tumornekrosefaktor
CA2247580A1 (en) 1997-10-03 1999-04-03 F. Hoffmann-La Roche Ag Process for preparing chiral succinic acid derivatives
EP0911324A1 (de) 1997-10-03 1999-04-28 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von chiralen Bernsteinsäurederivaten
EP0974590A1 (de) 1998-07-13 2000-01-26 F. Hoffmann-La Roche Ag Verfahren zur Herstellung chiraler Lactone durch asymetrische Hydrogenierung

Also Published As

Publication number Publication date
EP1052249A1 (de) 2000-11-15
KR100377695B1 (ko) 2003-03-29
JP2000344728A (ja) 2000-12-12
KR20000077225A (ko) 2000-12-26
DK1052249T3 (da) 2003-12-01
JO2258B1 (en) 2004-10-07
DE60004432T2 (de) 2004-06-24
CA2307994A1 (en) 2000-11-11
JP3382208B2 (ja) 2003-03-04
CN1156453C (zh) 2004-07-07
EP1052249B1 (de) 2003-08-13
ES2203370T3 (es) 2004-04-16
US6452010B1 (en) 2002-09-17
CN1274721A (zh) 2000-11-29
ATE247084T1 (de) 2003-08-15

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee