DE60001138T2 - Polycyclische Azaindolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents
Polycyclische Azaindolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische ZubereitungenInfo
- Publication number
- DE60001138T2 DE60001138T2 DE60001138T DE60001138T DE60001138T2 DE 60001138 T2 DE60001138 T2 DE 60001138T2 DE 60001138 T DE60001138 T DE 60001138T DE 60001138 T DE60001138 T DE 60001138T DE 60001138 T2 DE60001138 T2 DE 60001138T2
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- group
- alkoxy
- polyhaloalkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9912900A FR2799757B1 (fr) | 1999-10-15 | 1999-10-15 | Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60001138D1 DE60001138D1 (de) | 2003-02-13 |
DE60001138T2 true DE60001138T2 (de) | 2003-10-23 |
Family
ID=9550991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60001138T Expired - Fee Related DE60001138T2 (de) | 1999-10-15 | 2000-10-13 | Polycyclische Azaindolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Country Status (23)
Country | Link |
---|---|
US (3) | US6495543B1 (de) |
EP (1) | EP1092717B1 (de) |
JP (1) | JP3519357B2 (de) |
KR (1) | KR100460783B1 (de) |
CN (1) | CN1151152C (de) |
AT (1) | ATE230745T1 (de) |
AU (1) | AU772126B2 (de) |
BR (1) | BR0004823A (de) |
CA (1) | CA2323720C (de) |
DE (1) | DE60001138T2 (de) |
DK (1) | DK1092717T3 (de) |
EA (1) | EA003666B1 (de) |
ES (1) | ES2189730T3 (de) |
FR (1) | FR2799757B1 (de) |
HK (1) | HK1036061A1 (de) |
HU (1) | HUP0004007A3 (de) |
MX (1) | MXPA00009729A (de) |
NO (1) | NO317884B1 (de) |
NZ (1) | NZ507525A (de) |
PL (1) | PL343187A1 (de) |
PT (1) | PT1092717E (de) |
SI (1) | SI1092717T1 (de) |
ZA (1) | ZA200005667B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6269533B2 (en) * | 1999-02-23 | 2001-08-07 | Advanced Research Corporation | Method of making a patterned magnetic recording head |
FR2799757B1 (fr) * | 1999-10-15 | 2001-12-14 | Adir | Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
EP1132389A1 (de) * | 2000-03-06 | 2001-09-12 | Vernalis Research Limited | Neue Azaindolyl-Derivate für die Behandlung von Fettleibigheit |
DE10143079A1 (de) * | 2001-09-03 | 2003-05-15 | Zentaris Ag | Cyclische Indol- und Heteroindolderivate, deren Herstellung und Verwendung als Arzneimittel |
US20050267303A1 (en) * | 2001-09-04 | 2005-12-01 | Zentaris Ag | Cyclic indole and heteroindole derivatives and methods for making and using as pharmaceuticals |
GB0202015D0 (en) * | 2002-01-29 | 2002-03-13 | Hoffmann La Roche | Piperazine Derivatives |
US7595311B2 (en) * | 2002-05-24 | 2009-09-29 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
TWI329111B (en) * | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
NZ540842A (en) | 2002-11-28 | 2008-05-30 | Suven Life Sciences Ltd | N-arylsulfonyl-3-aminoalkoxyindoles |
EP1581538B1 (de) * | 2002-12-18 | 2007-02-28 | Suven Life Sciences Limited | Tetrazyklische 3-substituierte indole mit serotoninrezeptoraffinität |
DE202007014474U1 (de) * | 2007-10-16 | 2009-03-05 | Schwan-Stabilo Cosmetics Gmbh & Co. Kg | Aufgespritzte Applikatoren |
KR20110041495A (ko) * | 2008-07-30 | 2011-04-21 | 페레르 인터내쇼날 에스.에이. | 1,6-디하이드로-2h-3-옥사-6-아자-as-인다세네 화합물 |
US8546422B2 (en) | 2008-09-22 | 2013-10-01 | Merck Canada Inc. | Azaindole derivatives as CRTH2 receptor antagonists |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3912729A (en) * | 1972-02-14 | 1975-10-14 | Ayerst Mckenna & Harrison | Oxazinoindole- and thiazinoindole derivatives |
US3910901A (en) * | 1972-02-14 | 1975-10-07 | Ayerst Mckenna & Harrison | Oxazinoindole- and thiazinoindole derivatives |
US3962236A (en) * | 1972-02-14 | 1976-06-08 | Ayerst Mckenna And Harrison Ltd. | Oxazinoindole- and thiazinoindole derivatives |
US3910903A (en) * | 1974-02-14 | 1975-10-07 | Ayerst Mckenna & Harrison | Oxazinoindole- and thiazinoindole derivatives |
US4012511A (en) * | 1974-05-28 | 1977-03-15 | Ayerst Mckenna & Harrison Ltd. | Oxazinoindole derivatives useful as antidepressants |
US4066763A (en) * | 1975-07-07 | 1978-01-03 | Ayerst Mckenna And Harrison Ltd. | Thiazinoindoles useful as antidepressants |
EP0183993A3 (de) * | 1984-11-16 | 1987-12-09 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | 2H-Imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine und deren Verwendung als Unkrautbekämpfungsmittel |
DE3674028D1 (de) * | 1985-03-12 | 1990-10-18 | Ciba Geigy Ag | Heterocyclisch kondensierte pyridin-verbindungen als herbizide. |
DK155524C (da) * | 1987-03-18 | 1989-09-11 | Ferrosan As | Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse |
EP0572863A1 (de) * | 1992-06-05 | 1993-12-08 | F. Hoffmann-La Roche Ag | ZNS Pyrazinoindole |
MX9305947A (es) * | 1992-09-29 | 1994-06-30 | Smithkline Beecham Plc | Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen. |
FR2732969B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2762598A1 (fr) * | 1997-04-25 | 1998-10-30 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent |
FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2766824B1 (fr) * | 1997-07-30 | 1999-09-10 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
GB9902047D0 (en) * | 1999-01-29 | 1999-03-17 | Cerebrus Ltd | Chemical compounds XI |
FR2799757B1 (fr) * | 1999-10-15 | 2001-12-14 | Adir | Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
GB0019117D0 (en) * | 2000-08-03 | 2000-09-27 | Univ Barcelona | Derivatives of variolin B |
WO2004044732A1 (en) * | 2002-11-12 | 2004-05-27 | Zetera Corporation | Electrical devices with improved communication |
-
1999
- 1999-10-15 FR FR9912900A patent/FR2799757B1/fr not_active Expired - Fee Related
-
2000
- 2000-10-04 MX MXPA00009729A patent/MXPA00009729A/es active IP Right Grant
- 2000-10-12 US US09/689,578 patent/US6495543B1/en not_active Expired - Fee Related
- 2000-10-13 SI SI200030043T patent/SI1092717T1/xx unknown
- 2000-10-13 DK DK00402832T patent/DK1092717T3/da active
- 2000-10-13 BR BR0004823-2A patent/BR0004823A/pt not_active Application Discontinuation
- 2000-10-13 HU HU0004007A patent/HUP0004007A3/hu unknown
- 2000-10-13 CA CA002323720A patent/CA2323720C/fr not_active Expired - Fee Related
- 2000-10-13 EA EA200000948A patent/EA003666B1/ru not_active IP Right Cessation
- 2000-10-13 JP JP2000314109A patent/JP3519357B2/ja not_active Expired - Fee Related
- 2000-10-13 AT AT00402832T patent/ATE230745T1/de not_active IP Right Cessation
- 2000-10-13 NZ NZ507525A patent/NZ507525A/en unknown
- 2000-10-13 ZA ZA200005667A patent/ZA200005667B/xx unknown
- 2000-10-13 PL PL00343187A patent/PL343187A1/xx not_active Application Discontinuation
- 2000-10-13 PT PT00402832T patent/PT1092717E/pt unknown
- 2000-10-13 AU AU66502/00A patent/AU772126B2/en not_active Ceased
- 2000-10-13 EP EP00402832A patent/EP1092717B1/de not_active Expired - Lifetime
- 2000-10-13 ES ES00402832T patent/ES2189730T3/es not_active Expired - Lifetime
- 2000-10-13 DE DE60001138T patent/DE60001138T2/de not_active Expired - Fee Related
- 2000-10-13 CN CNB001304739A patent/CN1151152C/zh not_active Expired - Fee Related
- 2000-10-16 NO NO20005200A patent/NO317884B1/no not_active IP Right Cessation
- 2000-10-16 KR KR10-2000-0060725A patent/KR100460783B1/ko not_active IP Right Cessation
-
2001
- 2001-09-25 HK HK01106736A patent/HK1036061A1/xx not_active IP Right Cessation
-
2002
- 2002-10-09 US US10/267,303 patent/US7235550B2/en not_active Expired - Fee Related
- 2002-10-09 US US10/267,238 patent/US6667304B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |