DE50014532D1 - Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz - Google Patents

Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz

Info

Publication number
DE50014532D1
DE50014532D1 DE50014532T DE50014532T DE50014532D1 DE 50014532 D1 DE50014532 D1 DE 50014532D1 DE 50014532 T DE50014532 T DE 50014532T DE 50014532 T DE50014532 T DE 50014532T DE 50014532 D1 DE50014532 D1 DE 50014532D1
Authority
DE
Germany
Prior art keywords
desmethyl
tramadol
demethyltramadol
mono
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50014532T
Other languages
German (de)
English (en)
Inventor
Thomas Christoph
Elmar Friderichs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19947747A external-priority patent/DE19947747A1/de
Priority claimed from DE20002943U external-priority patent/DE20002943U1/de
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Application granted granted Critical
Publication of DE50014532D1 publication Critical patent/DE50014532D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE50014532T 1999-10-05 2000-09-27 Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz Expired - Lifetime DE50014532D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19947747A DE19947747A1 (de) 1999-10-05 1999-10-05 Verwendung von (+)-Tramadol, O-Demethyltramadol bzw. (+)-O-Demethyltramadol zur Therapie der Harninkontinenz
DE20002943U DE20002943U1 (de) 2000-02-21 2000-02-21 Arzneimittel enthaltend O-desmethyl-N-mono-desmethyl-tramadol
PCT/EP2000/009420 WO2001024783A2 (de) 1999-10-05 2000-09-27 Verwendung von (+)-tramadol, o-demethyltramadol bzw. (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol bzw. (+)-o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz

Publications (1)

Publication Number Publication Date
DE50014532D1 true DE50014532D1 (de) 2007-09-13

Family

ID=26055167

Family Applications (1)

Application Number Title Priority Date Filing Date
DE50014532T Expired - Lifetime DE50014532D1 (de) 1999-10-05 2000-09-27 Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz

Country Status (13)

Country Link
US (1) US6660774B2 (https=)
EP (1) EP1217998B1 (https=)
JP (1) JP5477881B2 (https=)
AT (1) ATE368455T1 (https=)
AU (1) AU7907600A (https=)
CA (1) CA2386381A1 (https=)
DE (1) DE50014532D1 (https=)
ES (1) ES2291223T3 (https=)
HK (1) HK1047707A1 (https=)
HU (1) HUP0202776A2 (https=)
MX (1) MXPA02003491A (https=)
PE (1) PE20010623A1 (https=)
WO (1) WO2001024783A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049483A1 (de) * 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte 1-Aminobutan-3-ol-Derivate
FR2815691B1 (fr) * 2000-10-20 2003-08-15 Valois Sa Bille de clapet
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
DE10224107A1 (de) * 2002-05-29 2003-12-11 Gruenenthal Gmbh Kombination ausgewählter Opioide mit anderen Wirkstoffen zur Therapie der Harninkontinenz
DE10224624A1 (de) * 2002-05-30 2003-12-11 Gruenenthal Gmbh Metabolite und Prodrugs von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol
DE10224556A1 (de) * 2002-05-31 2004-01-08 Grünenthal GmbH 1-Dimethylamino- 3-(3-methoxy-phenyl)2-methyl-pentan-3-ol entaltendes Arzneimittel in verschiedenen Formulierungen
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
US20050182131A1 (en) * 2002-07-19 2005-08-18 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
JP4059259B2 (ja) 2005-06-30 2008-03-12 ヤマハ株式会社 スピーカシステムおよびスピーカエンクロージャー
WO2007018234A1 (ja) * 2005-08-10 2007-02-15 Nippon Shinyaku Co., Ltd. 尿道内圧上昇作用剤
DK1940467T3 (da) 2005-09-09 2017-02-13 Paladin Labs Inc Lægemiddelsammensætning med langvarig frigivelse
CN101252932B (zh) 2005-09-09 2012-10-03 安吉利尼莱博法姆有限责任公司 用于一天给药一次的曲唑酮组合物
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
EP2281558A1 (en) * 2009-08-06 2011-02-09 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical compounds of O-Desmethyl-Tramadol and COX-inhibitors
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol
US11000488B2 (en) 2019-03-22 2021-05-11 Syntrix Biosystems Inc. Treating pain using desmetramadol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2095523C (en) 1991-09-06 2004-06-22 Robert B. Raffa Composition comprising a tramadol material and acetaminophen and its use
AU657351B2 (en) 1991-09-06 1995-03-09 Mcneilab, Inc. Compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE19601744C2 (de) 1996-01-19 1998-04-16 Gruenenthal Gmbh Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
EP0969818B1 (en) * 1997-03-11 2004-09-08 Arakis Ltd. Dosage forms comprising separate portions of r- and s-enantiomers
DE19712398A1 (de) * 1997-03-25 1998-10-01 Gruenenthal Gmbh Orale Anwendung von (+)-0-Demethyltramadol als Schmerzmittel
EP1005861B1 (en) 1997-04-11 2005-06-29 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence
GB9709972D0 (en) * 1997-05-19 1997-07-09 Pfizer Ltd Tetrazoles

Also Published As

Publication number Publication date
MXPA02003491A (es) 2002-08-20
PE20010623A1 (es) 2001-07-07
EP1217998B1 (de) 2007-08-01
CA2386381A1 (en) 2001-04-12
ATE368455T1 (de) 2007-08-15
ES2291223T3 (es) 2008-03-01
WO2001024783A2 (de) 2001-04-12
JP5477881B2 (ja) 2014-04-23
US20030069314A1 (en) 2003-04-10
AU7907600A (en) 2001-05-10
HK1047707A1 (zh) 2003-03-07
WO2001024783A3 (de) 2002-02-28
EP1217998A2 (de) 2002-07-03
HUP0202776A2 (hu) 2003-02-28
US6660774B2 (en) 2003-12-09
JP2003510350A (ja) 2003-03-18

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