HK1047707A1 - (+)-曲马朵、o-去甲曲马朵或(+)-o-去甲曲马朵、o-去甲-n-单-去甲-曲马朵或(+)-o-去甲-n-单-去甲-曲马朵治疗尿失禁的用途 - Google Patents

(+)-曲马朵、o-去甲曲马朵或(+)-o-去甲曲马朵、o-去甲-n-单-去甲-曲马朵或(+)-o-去甲-n-单-去甲-曲马朵治疗尿失禁的用途 Download PDF

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Publication number
HK1047707A1
HK1047707A1 HK02109384.3A HK02109384A HK1047707A1 HK 1047707 A1 HK1047707 A1 HK 1047707A1 HK 02109384 A HK02109384 A HK 02109384A HK 1047707 A1 HK1047707 A1 HK 1047707A1
Authority
HK
Hong Kong
Prior art keywords
desmethyl
tramadol
demethyltramadol
mono
urinary incontinence
Prior art date
Application number
HK02109384.3A
Other languages
English (en)
Chinese (zh)
Inventor
Christoph Thomas
Friderichs Elmar
Original Assignee
Grunenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19947747A external-priority patent/DE19947747A1/de
Priority claimed from DE20002943U external-priority patent/DE20002943U1/de
Application filed by Grunenthal Gmbh filed Critical Grunenthal Gmbh
Publication of HK1047707A1 publication Critical patent/HK1047707A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK02109384.3A 1999-10-05 2000-09-27 (+)-曲马朵、o-去甲曲马朵或(+)-o-去甲曲马朵、o-去甲-n-单-去甲-曲马朵或(+)-o-去甲-n-单-去甲-曲马朵治疗尿失禁的用途 HK1047707A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19991047747 1999-10-05
DE19947747A DE19947747A1 (de) 1999-10-05 1999-10-05 Verwendung von (+)-Tramadol, O-Demethyltramadol bzw. (+)-O-Demethyltramadol zur Therapie der Harninkontinenz
DE20002943U DE20002943U1 (de) 2000-02-21 2000-02-21 Arzneimittel enthaltend O-desmethyl-N-mono-desmethyl-tramadol
DE20002002943U 2000-02-21
PCT/EP2000/009420 WO2001024783A2 (de) 1999-10-05 2000-09-27 Verwendung von (+)-tramadol, o-demethyltramadol bzw. (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol bzw. (+)-o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz

Publications (1)

Publication Number Publication Date
HK1047707A1 true HK1047707A1 (zh) 2003-03-07

Family

ID=26055167

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02109384.3A HK1047707A1 (zh) 1999-10-05 2000-09-27 (+)-曲马朵、o-去甲曲马朵或(+)-o-去甲曲马朵、o-去甲-n-单-去甲-曲马朵或(+)-o-去甲-n-单-去甲-曲马朵治疗尿失禁的用途

Country Status (13)

Country Link
US (1) US6660774B2 (https=)
EP (1) EP1217998B1 (https=)
JP (1) JP5477881B2 (https=)
AT (1) ATE368455T1 (https=)
AU (1) AU7907600A (https=)
CA (1) CA2386381A1 (https=)
DE (1) DE50014532D1 (https=)
ES (1) ES2291223T3 (https=)
HK (1) HK1047707A1 (https=)
HU (1) HUP0202776A2 (https=)
MX (1) MXPA02003491A (https=)
PE (1) PE20010623A1 (https=)
WO (1) WO2001024783A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049483A1 (de) * 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte 1-Aminobutan-3-ol-Derivate
FR2815691B1 (fr) * 2000-10-20 2003-08-15 Valois Sa Bille de clapet
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
DE10224107A1 (de) * 2002-05-29 2003-12-11 Gruenenthal Gmbh Kombination ausgewählter Opioide mit anderen Wirkstoffen zur Therapie der Harninkontinenz
DE10224624A1 (de) * 2002-05-30 2003-12-11 Gruenenthal Gmbh Metabolite und Prodrugs von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol
DE10224556A1 (de) * 2002-05-31 2004-01-08 Grünenthal GmbH 1-Dimethylamino- 3-(3-methoxy-phenyl)2-methyl-pentan-3-ol entaltendes Arzneimittel in verschiedenen Formulierungen
DE10233048A1 (de) * 2002-07-19 2004-01-29 Grünenthal GmbH Verwendung von 1-Phenyl-3dimethylamino-propanverbindungen zur Therapie von depressiven Symptomatiken
US20050182131A1 (en) * 2002-07-19 2005-08-18 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl cyclohexane compounds and therapies for depressive symptoms, pain and incontinence
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
JP4059259B2 (ja) 2005-06-30 2008-03-12 ヤマハ株式会社 スピーカシステムおよびスピーカエンクロージャー
WO2007018234A1 (ja) * 2005-08-10 2007-02-15 Nippon Shinyaku Co., Ltd. 尿道内圧上昇作用剤
DK1940467T3 (da) 2005-09-09 2017-02-13 Paladin Labs Inc Lægemiddelsammensætning med langvarig frigivelse
CN101252932B (zh) 2005-09-09 2012-10-03 安吉利尼莱博法姆有限责任公司 用于一天给药一次的曲唑酮组合物
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
EP2281558A1 (en) * 2009-08-06 2011-02-09 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical compounds of O-Desmethyl-Tramadol and COX-inhibitors
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol
US11000488B2 (en) 2019-03-22 2021-05-11 Syntrix Biosystems Inc. Treating pain using desmetramadol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2095523C (en) 1991-09-06 2004-06-22 Robert B. Raffa Composition comprising a tramadol material and acetaminophen and its use
AU657351B2 (en) 1991-09-06 1995-03-09 Mcneilab, Inc. Compositions comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use
GB9202238D0 (en) 1992-02-03 1992-03-18 Wellcome Found Compounds
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE19601744C2 (de) 1996-01-19 1998-04-16 Gruenenthal Gmbh Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
EP0969818B1 (en) * 1997-03-11 2004-09-08 Arakis Ltd. Dosage forms comprising separate portions of r- and s-enantiomers
DE19712398A1 (de) * 1997-03-25 1998-10-01 Gruenenthal Gmbh Orale Anwendung von (+)-0-Demethyltramadol als Schmerzmittel
EP1005861B1 (en) 1997-04-11 2005-06-29 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence
GB9709972D0 (en) * 1997-05-19 1997-07-09 Pfizer Ltd Tetrazoles

Also Published As

Publication number Publication date
MXPA02003491A (es) 2002-08-20
PE20010623A1 (es) 2001-07-07
EP1217998B1 (de) 2007-08-01
CA2386381A1 (en) 2001-04-12
ATE368455T1 (de) 2007-08-15
ES2291223T3 (es) 2008-03-01
WO2001024783A2 (de) 2001-04-12
JP5477881B2 (ja) 2014-04-23
US20030069314A1 (en) 2003-04-10
AU7907600A (en) 2001-05-10
WO2001024783A3 (de) 2002-02-28
EP1217998A2 (de) 2002-07-03
HUP0202776A2 (hu) 2003-02-28
US6660774B2 (en) 2003-12-09
DE50014532D1 (de) 2007-09-13
JP2003510350A (ja) 2003-03-18

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