DE4338396A1 - N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung - Google Patents

N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung

Info

Publication number
DE4338396A1
DE4338396A1 DE4338396A DE4338396A DE4338396A1 DE 4338396 A1 DE4338396 A1 DE 4338396A1 DE 4338396 A DE4338396 A DE 4338396A DE 4338396 A DE4338396 A DE 4338396A DE 4338396 A1 DE4338396 A1 DE 4338396A1
Authority
DE
Germany
Prior art keywords
group
atom
amino
methyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE4338396A
Other languages
German (de)
English (en)
Inventor
Gerd Steiner
Rainer Munschauer
Liliane Unger
Hans-Juergen Teschendorf
Thomas Hoeger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to DE4338396A priority Critical patent/DE4338396A1/de
Priority to IL111375A priority patent/IL111375A/xx
Priority to PCT/EP1994/003583 priority patent/WO1995013279A1/de
Priority to BR9408029A priority patent/BR9408029A/pt
Priority to US08/640,751 priority patent/US5908844A/en
Priority to HU9601245A priority patent/HUT74691A/hu
Priority to EP95900102A priority patent/EP0728136A1/de
Priority to CA002175683A priority patent/CA2175683A1/en
Priority to JP7513562A priority patent/JPH09505283A/ja
Priority to AU81054/94A priority patent/AU681204B2/en
Publication of DE4338396A1 publication Critical patent/DE4338396A1/de
Priority to FI961977A priority patent/FI961977A/sv
Priority to US09/241,299 priority patent/US6096755A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE4338396A 1993-11-10 1993-11-10 N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung Withdrawn DE4338396A1 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE4338396A DE4338396A1 (de) 1993-11-10 1993-11-10 N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
IL111375A IL111375A (en) 1993-11-10 1994-10-24 N-substituted azabicycloalkane derivatives and pharmaceutical compositions containing them
HU9601245A HUT74691A (en) 1993-11-10 1994-10-31 N-substituted azabicycloalkane derivatives, their preparation and use
BR9408029A BR9408029A (pt) 1993-11-10 1994-10-31 Derivados de 3-azabicicloalcanos N-substituídos
US08/640,751 US5908844A (en) 1993-11-10 1994-10-31 N-substituted azabicycloalkane derivatives, their preparation and use
PCT/EP1994/003583 WO1995013279A1 (de) 1993-11-10 1994-10-31 N-substituierte azabicycloalkan-derivate, ihre herstellung und verwendung
EP95900102A EP0728136A1 (de) 1993-11-10 1994-10-31 N-substituierte azabicycloalkan-derivate, ihre herstellung und verwendung
CA002175683A CA2175683A1 (en) 1993-11-10 1994-10-31 N-substituted azabicycloalkane derivatives, their preparation and use
JP7513562A JPH09505283A (ja) 1993-11-10 1994-10-31 Ｎ−置換アザビシクロアルカン誘導体、その製造および使用
AU81054/94A AU681204B2 (en) 1993-11-10 1994-10-31 N-substituted azabicycloalkane derivatives, their preparation and use
FI961977A FI961977A (sv) 1993-11-10 1996-05-09 N-substituerade azabicykloalkanderivat, deras framställning och användning
US09/241,299 US6096755A (en) 1993-11-10 1999-02-01 N-substituted azabicycloalkane derivatives, their preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4338396A DE4338396A1 (de) 1993-11-10 1993-11-10 N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
DE4338396A1 true DE4338396A1 (de) 1995-05-11

Family

ID=6502267

Family Applications (1)

Application Number Title Priority Date Filing Date
DE4338396A Withdrawn DE4338396A1 (de) 1993-11-10 1993-11-10 N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung

Country Status (11)

Country Link
US (2) US5908844A (sv)
EP (1) EP0728136A1 (sv)
JP (1) JPH09505283A (sv)
AU (1) AU681204B2 (sv)
BR (1) BR9408029A (sv)
CA (1) CA2175683A1 (sv)
DE (1) DE4338396A1 (sv)
FI (1) FI961977A (sv)
HU (1) HUT74691A (sv)
IL (1) IL111375A (sv)
WO (1) WO1995013279A1 (sv)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007113232A1 (en) 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. 0] hexyl derivatives as modulators of dopamine d3 receptors
WO2007113260A1 (en) 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
WO2007125061A1 (en) * 2006-04-27 2007-11-08 Glaxo Group Limited Spirocompounds useful as modulators for dopamine d3 receptors
CZ303926B6 (cs) * 1999-01-12 2013-06-26 Abbott Gmbh & Co. Kg. Derivát triazolu a farmaceutický prostredek s jeho obsahem

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7963904B2 (en) * 2000-09-29 2011-06-21 Delisle Clarence A Method and device for treating body ailments
SE0100326D0 (sv) 2001-02-02 2001-02-02 Astrazeneca Ab New compounds
WO2005121145A2 (en) 2004-06-09 2005-12-22 F. Hoffmann-La Roche Ag Octahydro-pyrrolo[3,4-c] derivatives and their use as antiviral compounds
US7665658B2 (en) 2005-06-07 2010-02-23 First Data Corporation Dynamic aggregation of payment transactions
GB0719235D0 (en) 2007-10-02 2007-11-14 Glaxo Group Ltd Novel compounds
US20220227773A1 (en) * 2019-05-30 2022-07-21 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Fused ring compound, preparation method therefor and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155668A (en) * 1960-04-11 1964-11-03 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl)-lower-alkyl]-tertiary amines and intermediates therefor
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
US4548938A (en) * 1981-07-15 1985-10-22 Janssen Pharmaceutica N.V. 5-H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one compounds
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
US5532243A (en) * 1992-02-14 1996-07-02 The Dupont Merck Pharmaceutical Company Antipsychotic nitrogen-containing bicyclic compounds
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ303926B6 (cs) * 1999-01-12 2013-06-26 Abbott Gmbh & Co. Kg. Derivát triazolu a farmaceutický prostredek s jeho obsahem
WO2007113232A1 (en) 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. 0] hexyl derivatives as modulators of dopamine d3 receptors
WO2007113260A1 (en) 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
US8222266B2 (en) 2006-04-03 2012-07-17 Glaxo Group Limited Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors
WO2007125061A1 (en) * 2006-04-27 2007-11-08 Glaxo Group Limited Spirocompounds useful as modulators for dopamine d3 receptors
US8030322B2 (en) 2006-04-27 2011-10-04 Glaxo Group Limited Spirocompounds useful as modulators for dopamine D3 receptors

Also Published As

Publication number Publication date
JPH09505283A (ja) 1997-05-27
AU681204B2 (en) 1997-08-21
IL111375A (en) 1997-06-10
HU9601245D0 (en) 1996-07-29
FI961977A0 (sv) 1996-05-09
CA2175683A1 (en) 1995-05-18
FI961977A (sv) 1996-05-09
WO1995013279A1 (de) 1995-05-18
EP0728136A1 (de) 1996-08-28
BR9408029A (pt) 1996-12-17
US5908844A (en) 1999-06-01
HUT74691A (en) 1997-01-28
IL111375A0 (en) 1994-12-29
US6096755A (en) 2000-08-01
AU8105494A (en) 1995-05-29

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Legal Events

Date Code Title Description
8130 Withdrawal