DE3886965T2 - Zubereitungen zur gesteuerten Wirkstofffreisetzung. - Google Patents

Zubereitungen zur gesteuerten Wirkstofffreisetzung.

Info

Publication number
DE3886965T2
DE3886965T2 DE3886965T DE3886965T DE3886965T2 DE 3886965 T2 DE3886965 T2 DE 3886965T2 DE 3886965 T DE3886965 T DE 3886965T DE 3886965 T DE3886965 T DE 3886965T DE 3886965 T2 DE3886965 T2 DE 3886965T2
Authority
DE
Germany
Prior art keywords
preparations
drug release
controlled drug
controlled
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3886965T
Other languages
English (en)
Other versions
DE3886965D1 (de
Inventor
Shin-Ichi Akimoto
Susumu Honda
Tohru Yasukohchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NOF Corp
Original Assignee
Nippon Oil and Fats Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Oil and Fats Co Ltd filed Critical Nippon Oil and Fats Co Ltd
Application granted granted Critical
Publication of DE3886965D1 publication Critical patent/DE3886965D1/de
Publication of DE3886965T2 publication Critical patent/DE3886965T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/04Anhydrides, e.g. cyclic anhydrides
    • C08F222/06Maleic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/14Esterification
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/30Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/42Introducing metal atoms or metal-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10Copolymer characterised by the proportions of the comonomers expressed as molar percentages
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/30Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
DE3886965T 1987-03-14 1988-03-14 Zubereitungen zur gesteuerten Wirkstofffreisetzung. Expired - Lifetime DE3886965T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62057926A JPH0644927B2 (ja) 1987-03-14 1987-03-14 徐放性活性成分放出剤

Publications (2)

Publication Number Publication Date
DE3886965D1 DE3886965D1 (de) 1994-02-24
DE3886965T2 true DE3886965T2 (de) 1994-06-16

Family

ID=13069608

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3886965T Expired - Lifetime DE3886965T2 (de) 1987-03-14 1988-03-14 Zubereitungen zur gesteuerten Wirkstofffreisetzung.

Country Status (5)

Country Link
US (2) US5081111A (de)
EP (1) EP0282951B1 (de)
JP (1) JPH0644927B2 (de)
DE (1) DE3886965T2 (de)
DK (1) DK170631B1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946918A (en) * 1987-11-06 1990-08-07 Nippon Oil And Fats Co., Ltd. Synthetic resin compatibilizer
DE68920697T2 (de) * 1988-10-31 1995-06-22 Takiron Co Insektenvertreibungsmittel mit gesteuerter Freisetzung.
JP2692202B2 (ja) * 1988-11-29 1997-12-17 日本油脂株式会社 無機粉末の油中分散安定剤
CA1339231C (en) * 1989-03-30 1997-08-05 Ratana Kanluen Polyfunctional polymers as deinking agents
US5250205A (en) * 1989-04-26 1993-10-05 Nippon Oil And Fats Co., Ltd. Lubricating oil
JP2844804B2 (ja) * 1989-04-26 1999-01-13 日本油脂株式会社 潤滑油
CA2020964A1 (en) * 1989-07-12 1991-01-13 Emmett M. Partain, Iii Pharmaceutical active derivative delivery systems
US5516689A (en) * 1993-04-30 1996-05-14 Solvay Enzymes, Inc. Method for the treatment of sticky cotton fiber with transglucosidase from Aspergillus niger
DE69534385T2 (de) 1994-11-10 2006-07-06 Kanebo Cosmetics, Inc. Duftstoff mit verzögerter freisetzung und verfahren zur detektion von mikroorganismen durch diesen duftstoff
CA2209315C (en) * 1995-01-06 2009-12-15 Australian Biomedical Company Pty.Ltd. Gibberellins compounds for veterinary and medicinal applications
DE19513126A1 (de) * 1995-04-07 1996-10-10 Sueddeutsche Kalkstickstoff Copolymere auf Basis von Oxyalkylenglykol-Alkenylethern und ungesättigten Dicarbonsäure-Derivaten
DE19517504A1 (de) * 1995-05-12 1996-11-14 Haarmann & Reimer Gmbh Borsäureester und ihre Verwendung als Riechstoffe
US5559088A (en) * 1995-07-07 1996-09-24 The Proctor & Gamble Company Dryer-activated fabric conditioning and antistatic compositions with improved perfume longevity
US5531910A (en) * 1995-07-07 1996-07-02 The Procter & Gamble Company Biodegradable fabric softener compositions with improved perfume longevity
US5562847A (en) * 1995-11-03 1996-10-08 The Procter & Gamble Company Dryer-activated fabric conditioning and antistatic compositions with improved perfume longevity
WO1998007809A2 (en) 1996-08-19 1998-02-26 The Procter & Gamble Company HARD SURFACE CLEANERS COMPRISING β-KETOESTER PRO-FRAGRANCES
US6126953A (en) * 1996-08-19 2000-10-03 The Procter & Gamble Company Fragrance delivery systems for personal care articles
US6100233A (en) * 1996-08-19 2000-08-08 The Procter & Gamble Company Odor control compositions comprising β-ketoester pro-fragrances
US6093691A (en) * 1996-08-19 2000-07-25 The Procter & Gamble Company Rinse added fabric softening compositions and method of use for the delivery of fragrance derivatives
US6150310A (en) * 1996-08-19 2000-11-21 The Procter & Gamble Company Laundry detergent compositions comprising β-ketoester pro-fragrances
EP0831143A1 (de) * 1996-09-19 1998-03-25 The Procter & Gamble Company Ein oder mehrere aktive Alkohole enthaltende polymere Verbindung
AU7139198A (en) 1997-04-24 1998-11-13 Procter & Gamble Company, The Orthocarbonate pro-fragrances
US6087322A (en) 1997-04-24 2000-07-11 The Procter & Gamble Company Fragrance pro-accords
AU744085B2 (en) * 1997-06-06 2002-02-14 Kyowa Hakko Kirin Co., Ltd. Chemically modified polypeptides
AR016292A1 (es) 1997-06-27 2001-07-04 Procter & Gamble Compuesto pro-fragancia, composicion detergente para lavar la ropa, composiciones suavizantes de tejidos y composicion que comprende un sustrato que lo contienen
US6083892A (en) * 1997-08-19 2000-07-04 The Procter & Gamble Company Automatic dishwashing detergents comprising β-ketoester pro-fragrances
US6313201B1 (en) * 1997-12-25 2001-11-06 Mitsubishi Gas Chemical Company, Inc. Modified catalase, a composition thereof and process for preparing the catalase
DE10012949A1 (de) * 2000-03-16 2001-09-27 Henkel Kgaa Kieselsäureester-Mischungen
GB0123232D0 (en) * 2001-09-26 2001-11-21 Smith & Nephew Polymers
FR2832630B1 (fr) 2001-11-28 2005-01-14 Oreal Composition cosmetique et/ou dermatologique contenant au moins un actif hydrophile sensible a l'oxydation stabilise par au moins un copolymere de n-vinylimidazole
EP1374849B1 (de) * 2002-06-20 2005-11-23 L'oreal Kosmetische und/oder dermatologische Verwendung einer Zusammensetzung, die mindestens einen oxidationsempfindlichen hydrophilen durch mindestens einem Polymer oder Copolymer stabilisierten Wirkstoff aus Maleinsäureanhydrid enthält
AR050286A1 (es) * 2004-08-06 2006-10-11 Nippon Soda Co Una formulacion quimica agricola de liberacion controlada
US20060166855A1 (en) * 2005-01-25 2006-07-27 Howard Murad Fragrance delivery system
FR2886845B1 (fr) * 2005-06-13 2009-07-03 Oreal Produit cosmetique solide
US20070224233A1 (en) * 2005-08-05 2007-09-27 Nippon Soda Co., Ltd Controlled-Release Agricultural Chemical Formulation
EP2377396B1 (de) * 2006-02-06 2017-08-30 Nippon Soda Co., Ltd. Harzzusammensetzung mit freisetzungsgesteuerter agrarchemikalie, herstellungsverfahren und agrarchemikalienformulierung
EP2088855B1 (de) 2006-11-30 2010-03-24 Basf Se Agrarchemikalische formulierungen, umfassend copolymere auf basis von ethylenisch ungesättigten dicarbonsäuremono- und -diestern
CN101562969B (zh) 2006-11-30 2013-12-25 巴斯夫欧洲公司 包含1-乙烯基-2-吡咯烷酮共聚物的农业化学配制剂
US8796248B2 (en) * 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2090596A1 (de) 2008-02-13 2009-08-19 Construction Research and Technology GmbH Copolymer mit Polyetherseitenketten und Hydroxyalkyl- und Säurebausteinen
US7973110B2 (en) * 2008-06-16 2011-07-05 Construction Research & Technology Gmbh Copolymer synthesis process
US11014070B2 (en) * 2016-03-14 2021-05-25 3M Innovative Properties Company Composite granules including polymeric sorbent for reactive gases
RU2704211C1 (ru) 2016-03-14 2019-10-24 3М Инновейтив Пропертиз Компани Воздушные фильтры, содержащие полимерные сорбенты для химически активных газов
US10960341B2 (en) 2016-03-14 2021-03-30 3M Innovative Properties Company Air filters comprising polymeric sorbents for aldehydes
CN113068705B (zh) * 2021-03-26 2021-09-28 江南大学 一种桉油精乳液的制备方法及其在生物农药的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS167530B1 (en) * 1972-03-29 1976-04-29 Jiri Coupek Method of insoluble biologically active compounds preparation
CA1150635A (en) * 1979-10-23 1983-07-26 Philip L. Williams Lipophilic group in hydrophilic polymer with entrapped volatile ingredient
JPS587649B2 (ja) * 1980-03-25 1983-02-10 大阪大学長 Nad↑+−ポリエチレングリコ−ル誘導体
EP0056627B1 (de) * 1981-01-16 1984-10-03 Nippon Shokubai Kagaku Kogyo Co., Ltd Copolymer und Verfahren zu seiner Herstellung
US4435524A (en) * 1981-09-08 1984-03-06 The B. F. Goodrich Company Process for preparing spherical and porous vinyl resin particles
DE3381105D1 (de) * 1982-08-12 1990-02-22 Kanegafuchi Chemical Ind Aktivierung biovertraeglicher terpolymere mit biologischen stoffen, deren anzubindende komplemente pathologische effektoren sind.
JPS59104323A (ja) * 1982-12-07 1984-06-16 Ajinomoto Co Inc 代用血液

Also Published As

Publication number Publication date
DK137488D0 (da) 1988-03-14
US5081111A (en) 1992-01-14
EP0282951B1 (de) 1994-01-12
DK170631B1 (da) 1995-11-20
DE3886965D1 (de) 1994-02-24
JPH0644927B2 (ja) 1994-06-15
JPS63226358A (ja) 1988-09-21
EP0282951A2 (de) 1988-09-21
EP0282951A3 (en) 1990-07-25
US5320837A (en) 1994-06-14
DK137488A (da) 1988-09-15

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Legal Events

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