DE3873786T2 - Substituierte 1,3,4,9-tetrahydropyrano(3,4-b)indol-1-essigsaeuren. - Google Patents

Substituierte 1,3,4,9-tetrahydropyrano(3,4-b)indol-1-essigsaeuren.

Info

Publication number
DE3873786T2
DE3873786T2 DE8888300820T DE3873786T DE3873786T2 DE 3873786 T2 DE3873786 T2 DE 3873786T2 DE 8888300820 T DE8888300820 T DE 8888300820T DE 3873786 T DE3873786 T DE 3873786T DE 3873786 T2 DE3873786 T2 DE 3873786T2
Authority
DE
Germany
Prior art keywords
tetrahydropyrano
indol
substituted
acetic acids
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888300820T
Other languages
English (en)
Other versions
DE3873786D1 (de
Inventor
Brian Alexander Mckittrick
Alan Howard Katz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of DE3873786D1 publication Critical patent/DE3873786D1/de
Publication of DE3873786T2 publication Critical patent/DE3873786T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8888300820T 1987-02-20 1988-02-01 Substituierte 1,3,4,9-tetrahydropyrano(3,4-b)indol-1-essigsaeuren. Expired - Fee Related DE3873786T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000530253A CA1319695C (en) 1987-02-20 1987-02-20 Substituted 1,3,4,9-tetrahydropyrano¬3,4-b|- indole-1-acetic acids

Publications (2)

Publication Number Publication Date
DE3873786D1 DE3873786D1 (de) 1992-09-24
DE3873786T2 true DE3873786T2 (de) 1993-01-21

Family

ID=4135020

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888300820T Expired - Fee Related DE3873786T2 (de) 1987-02-20 1988-02-01 Substituierte 1,3,4,9-tetrahydropyrano(3,4-b)indol-1-essigsaeuren.

Country Status (8)

Country Link
US (2) US4785015A (de)
EP (1) EP0279548B1 (de)
JP (1) JP2733490B2 (de)
AT (1) ATE79625T1 (de)
CA (1) CA1319695C (de)
DE (1) DE3873786T2 (de)
ES (1) ES2042727T3 (de)
GR (1) GR3006108T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822781A (en) * 1987-10-08 1989-04-18 American Home Products Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
TW200400818A (en) 2002-05-21 2004-01-16 Wyeth Corp Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus
US20060058532A1 (en) * 2004-09-10 2006-03-16 Warren Chew Process for the scalable synthesis of 1,3,4,9-tetrahydropyrano[3,4-b]-indole derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3939178A (en) * 1971-06-01 1976-02-17 American Home Products Corporation Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles
IE59728B1 (en) * 1986-03-11 1994-03-23 American Home Prod Substituted 1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acids
US4686213A (en) * 1986-08-15 1987-08-11 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids

Also Published As

Publication number Publication date
GR3006108T3 (de) 1993-06-21
US4785015A (en) 1988-11-15
EP0279548A1 (de) 1988-08-24
CA1319695C (en) 1993-06-29
EP0279548B1 (de) 1992-08-19
JPS63208588A (ja) 1988-08-30
JP2733490B2 (ja) 1998-03-30
DE3873786D1 (de) 1992-09-24
ATE79625T1 (de) 1992-09-15
US4904799A (en) 1990-02-27
ES2042727T3 (es) 1993-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee