DE3856567D1 - Lumineszente Rhenium-Komplexe und Verfahren zur Herstellung - Google Patents
Lumineszente Rhenium-Komplexe und Verfahren zur HerstellungInfo
- Publication number
- DE3856567D1 DE3856567D1 DE3856567T DE3856567T DE3856567D1 DE 3856567 D1 DE3856567 D1 DE 3856567D1 DE 3856567 T DE3856567 T DE 3856567T DE 3856567 T DE3856567 T DE 3856567T DE 3856567 D1 DE3856567 D1 DE 3856567D1
- Authority
- DE
- Germany
- Prior art keywords
- ligand
- electrochemiluminescent
- chemical moiety
- integer equal
- ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003281 rhenium Chemical class 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 5
- 239000000126 substance Substances 0.000 abstract 5
- 230000005670 electromagnetic radiation Effects 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229910052702 rhenium Inorganic materials 0.000 abstract 1
- WUAPFZMCVAUBPE-UHFFFAOYSA-N rhenium atom Chemical compound [Re] WUAPFZMCVAUBPE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/22—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/48—Aldehydo radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Electroluminescent Light Sources (AREA)
- Luminescent Compositions (AREA)
- Peptides Or Proteins (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11701787A | 1987-11-04 | 1987-11-04 | |
US117017 | 1987-11-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3856567D1 true DE3856567D1 (de) | 2004-03-11 |
DE3856567T2 DE3856567T2 (de) | 2004-12-16 |
Family
ID=22370562
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3856567T Expired - Lifetime DE3856567T2 (de) | 1987-11-04 | 1988-11-04 | Lumineszente Rhenium-Komplexe und Verfahren zur Herstellung |
DE3855535T Expired - Lifetime DE3855535T2 (de) | 1987-11-04 | 1988-11-04 | Elektrochemilumineszente rhenium-fraktionen und verfahren |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3855535T Expired - Lifetime DE3855535T2 (de) | 1987-11-04 | 1988-11-04 | Elektrochemilumineszente rhenium-fraktionen und verfahren |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP0339086B1 (de) |
JP (2) | JP2538083B2 (de) |
AT (2) | ATE259064T1 (de) |
AU (1) | AU2827389A (de) |
CA (1) | CA1340460C (de) |
DE (2) | DE3856567T2 (de) |
SG (1) | SG54160A1 (de) |
WO (1) | WO1989004302A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA929351B (en) * | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
US5541113A (en) * | 1993-09-22 | 1996-07-30 | Beckman Instruments, Inc. | Method for detecting an analyte using an electrochemical luminescent transition metal label |
JP2909216B2 (ja) * | 1994-04-29 | 1999-06-23 | パーキン‐エルマー コーポレイション | 核酸増幅生成物のリアルタイム検出装置 |
US5744367A (en) * | 1994-11-10 | 1998-04-28 | Igen International, Inc. | Magnetic particle based electrochemiluminescent detection apparatus and method |
DE69637001T2 (de) * | 1995-06-07 | 2007-12-06 | Bioveris Corp. | Elektrochemilumineszenz-enzymimmunoassay |
CA2205050A1 (en) * | 1995-09-12 | 1997-03-20 | Yuzaburo Namba | Method and apparatus for measuring electrochemiluminescent emission |
US6146838A (en) * | 1997-03-18 | 2000-11-14 | Igen International, Inc. | Detecting water-borne parasites using electrochemiluminescence |
US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
WO2004020549A1 (ja) * | 2002-08-27 | 2004-03-11 | Fujitsu Limited | 有機金属錯体、有機el素子及び有機elディスプレイ |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
WO2005093418A1 (ja) * | 2004-03-26 | 2005-10-06 | Toto, Ltd. | 光電流を用いた被検物質の特異的検出方法、それに用いられる電極、測定用セル、測定装置、および緩衝溶液 |
US20060020192A1 (en) | 2004-07-13 | 2006-01-26 | Dexcom, Inc. | Transcutaneous analyte sensor |
JP4328704B2 (ja) * | 2004-10-14 | 2009-09-09 | キヤノン株式会社 | 有機エレクトロルミネッセンス素子及びこれを用いた表示装置 |
US8264347B2 (en) | 2008-06-24 | 2012-09-11 | Trelleborg Sealing Solutions Us, Inc. | Seal system in situ lifetime measurement |
JP2013180943A (ja) * | 2012-03-05 | 2013-09-12 | Nippon Telegr & Teleph Corp <Ntt> | 二酸化炭素還元方法および還元用光触媒ならびにその製造方法 |
US10644251B2 (en) | 2013-12-04 | 2020-05-05 | Universal Display Corporation | Organic electroluminescent materials and devices |
CN113522364B (zh) * | 2021-07-19 | 2022-05-06 | 中国地质大学(北京) | 化学发光增强剂及制备和在过氧化氢高碘酸盐体系的应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL49685A (en) | 1976-05-31 | 1978-10-31 | Technion Res & Dev Foundation | Specific binding assay method for determining the concentration of materials and reagent means therefor |
US4280815A (en) | 1979-06-18 | 1981-07-28 | Technicon Instruments Corporation | Electrochemiluminescent immunoassay and apparatus therefor |
US4372745A (en) | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
US4292654A (en) * | 1979-12-20 | 1981-09-29 | Rca Corporation | Deflection system and switched-mode power supply using a common ramp generator |
US4293310A (en) | 1980-03-14 | 1981-10-06 | University Of Pittsburgh | Photoelectrochemical immunoassay |
US4464679A (en) * | 1981-07-06 | 1984-08-07 | Rca Corporation | Method and apparatus for operating a microprocessor in synchronism with a video signal |
US4412064A (en) * | 1982-08-09 | 1983-10-25 | Armco Inc. | Metal atom containing epoxy resins |
US4732864A (en) * | 1983-10-06 | 1988-03-22 | E. I. Du Pont De Nemours And Company | Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules |
US4707440A (en) * | 1984-01-30 | 1987-11-17 | Enzo Biochem, Inc. | Nucleic acid hybridization assay and detectable molecules useful in such assay |
US4652440A (en) * | 1984-05-03 | 1987-03-24 | Paik Chang H | Method of stably radiolabeling antibodies with technetium and rhenium |
US4659839A (en) * | 1984-10-10 | 1987-04-21 | Mallinckrodt, Inc. | Coupling agents for radiolabeled antibody fragments |
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
-
1988
- 1988-11-04 AT AT95201320T patent/ATE259064T1/de not_active IP Right Cessation
- 1988-11-04 DE DE3856567T patent/DE3856567T2/de not_active Expired - Lifetime
- 1988-11-04 WO PCT/US1988/003947 patent/WO1989004302A1/en active IP Right Grant
- 1988-11-04 EP EP89900708A patent/EP0339086B1/de not_active Expired - Lifetime
- 1988-11-04 JP JP1500534A patent/JP2538083B2/ja not_active Expired - Fee Related
- 1988-11-04 DE DE3855535T patent/DE3855535T2/de not_active Expired - Lifetime
- 1988-11-04 EP EP95201320A patent/EP0674176B1/de not_active Expired - Lifetime
- 1988-11-04 AU AU28273/89A patent/AU2827389A/en not_active Abandoned
- 1988-11-04 CA CA000582281A patent/CA1340460C/en not_active Expired - Fee Related
- 1988-11-04 AT AT89900708T patent/ATE142622T1/de not_active IP Right Cessation
- 1988-11-04 SG SG1996002892A patent/SG54160A1/en unknown
-
1993
- 1993-08-13 JP JP5201648A patent/JP2718618B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0339086A1 (de) | 1989-11-02 |
EP0674176B1 (de) | 2004-02-04 |
JP2538083B2 (ja) | 1996-09-25 |
SG54160A1 (en) | 1998-11-16 |
EP0339086A4 (de) | 1990-02-20 |
EP0674176A1 (de) | 1995-09-27 |
ATE142622T1 (de) | 1996-09-15 |
WO1989004302A1 (en) | 1989-05-18 |
AU2827389A (en) | 1989-06-01 |
ATE259064T1 (de) | 2004-02-15 |
DE3856567T2 (de) | 2004-12-16 |
JPH06186164A (ja) | 1994-07-08 |
DE3855535D1 (de) | 1996-10-17 |
DE3855535T2 (de) | 1997-01-16 |
JP2718618B2 (ja) | 1998-02-25 |
JPH02501749A (ja) | 1990-06-14 |
CA1340460C (en) | 1999-03-23 |
EP0339086B1 (de) | 1996-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: BIOVERIS CORP.(N.D.GES.D.STAATES DELAWARE), GAITHE |
|
8364 | No opposition during term of opposition |