DE3822310C2 - - Google Patents

Info

Publication number
DE3822310C2
DE3822310C2 DE3822310A DE3822310A DE3822310C2 DE 3822310 C2 DE3822310 C2 DE 3822310C2 DE 3822310 A DE3822310 A DE 3822310A DE 3822310 A DE3822310 A DE 3822310A DE 3822310 C2 DE3822310 C2 DE 3822310C2
Authority
DE
Germany
Prior art keywords
particles
detectors
pulses
light
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3822310A
Other languages
German (de)
English (en)
Other versions
DE3822310A1 (de
Inventor
Kazuo Kokubunji Jp Takeda
Yoshitoshi Ome Jp Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Publication of DE3822310A1 publication Critical patent/DE3822310A1/de
Application granted granted Critical
Publication of DE3822310C2 publication Critical patent/DE3822310C2/de
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE3822310A 1987-07-03 1988-07-01 Vorrichtung zur messung von teilchencharakteristika Granted DE3822310A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62165176A JP2642632B2 (ja) 1987-07-03 1987-07-03 微粒子計測装置および微粒子計測方法

Publications (2)

Publication Number Publication Date
DE3822310A1 DE3822310A1 (de) 1989-01-12
DE3822310C2 true DE3822310C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-07-18

Family

ID=15807297

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3822310A Granted DE3822310A1 (de) 1987-07-03 1988-07-01 Vorrichtung zur messung von teilchencharakteristika

Country Status (3)

Country Link
US (1) US4957363A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2642632B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3822310A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JP3187129B2 (ja) * 1992-04-01 2001-07-11 シスメックス株式会社 粒子分析装置
DE4305645C2 (de) * 1993-02-24 1996-10-02 Rwe Entsorgung Ag Verfahren zur Ermittlung charakteristischer Eigenschaften von Radikale bildenden Prozessen, Verwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
NO930980L (no) * 1993-03-18 1994-09-19 Flowtech As Optisk konfigurasjon for væskeströmcytofotometer
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US5528045A (en) * 1995-04-06 1996-06-18 Becton Dickinson And Company Particle analyzer with spatially split wavelength filter
RU2205382C2 (ru) 1995-04-06 2003-05-27 Альфа Лаваль Агри Аб Способ и устройство для количественного определения частиц в жидких средах
US5682231A (en) * 1995-07-06 1997-10-28 Holsen; John R. Device and method for determining contamination of a light permeable material utilizing the values of detected light below the saturation intensity of a sensor
GB9606423D0 (en) * 1996-03-27 1996-06-05 Univ Hertfordshire An instrument for the real-time classification of particle shape within clouds and aerosols
US5844685A (en) * 1996-07-30 1998-12-01 Bayer Corporation Reference laser beam sampling apparatus
EP2264427B1 (en) 1997-01-31 2017-05-03 Xy, Llc Optical apparatus with focussing reflector for converging radiation onto a flow of particles, and related method of analysis
JPH10300671A (ja) * 1997-04-22 1998-11-13 Yokogawa Electric Corp 微粒子計測装置
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
JP3393817B2 (ja) * 1998-10-16 2003-04-07 株式会社堀場製作所 粒径分布測定装置
GB9901406D0 (en) * 1999-01-23 1999-03-10 Harley Scient Limited Airborne particle detector
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
GB0103757D0 (en) * 2001-02-16 2001-04-04 Univ Hertfordshire Methods and apparatus for the detection and characterisation of liquid-borne a rticles
JP4266075B2 (ja) * 2001-02-19 2009-05-20 株式会社堀場製作所 粒径分布測定装置
US20030207441A1 (en) * 2002-05-01 2003-11-06 Eyster Curt R. Devices and methods for analyte concentration determination
US6847451B2 (en) * 2002-05-01 2005-01-25 Lifescan, Inc. Apparatuses and methods for analyte concentration determination
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
CN1674780A (zh) 2002-08-01 2005-09-28 Xy公司 低压精子分离系统
MXPA05001654A (es) 2002-08-15 2005-10-18 Xy Inc Citometro de flujo de alta resolucion.
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US6859276B2 (en) * 2003-01-24 2005-02-22 Coulter International Corp. Extracted polarization intensity differential scattering for particle characterization
EP2305172B1 (en) 2003-03-28 2016-05-11 Inguran, LLC Apparatus and methods for providing sex-sorted animal sperm
AU2004242121B2 (en) 2003-05-15 2010-06-24 Xy, Llc. Efficient haploid cell sorting for flow cytometer systems
US7298478B2 (en) 2003-08-14 2007-11-20 Cytonome, Inc. Optical detector for a particle sorting system
DE102004047417B4 (de) * 2003-09-29 2007-01-04 Gebauer, Gerd, Dr. Makromolekül- und Aerosoldiagnostik in gasförmiger und flüssiger Umgebung
US7430480B2 (en) * 2003-10-07 2008-09-30 Matsushita Electric Industrial Co., Ltd. Particulate determination method
EP1730266A2 (en) 2004-03-29 2006-12-13 Monsanto Technology, LLC Sperm suspensions for sorting into x or y chromosome-bearing enriched populations
BRPI0513685A (pt) 2004-07-22 2008-05-13 Monsanto Technology Llc processo para enriquecimento de uma população de células de esperma
US7612871B2 (en) * 2004-09-01 2009-11-03 Honeywell International Inc Frequency-multiplexed detection of multiple wavelength light for flow cytometry
US7630075B2 (en) * 2004-09-27 2009-12-08 Honeywell International Inc. Circular polarization illumination based analyzer system
JP5473931B2 (ja) * 2007-11-16 2014-04-16 パーティクル・メージャーリング・システムズ・インコーポレーテッド 光学粒子計数器を較正検証するためのシステム及び方法
CN101925809B (zh) 2007-12-04 2013-03-27 粒子监测系统有限公司 用于粒子检测的二维光学成像方法和系统
US8610085B2 (en) * 2009-08-20 2013-12-17 Bio-Rad Laboratories, Inc. High-speed cellular cross sectional imaging
GB2494733A (en) * 2011-09-14 2013-03-20 Malvern Instr Ltd Measuring particle size distribution by light scattering
JP6121319B2 (ja) * 2013-03-29 2017-04-26 シスメックス株式会社 粒子測定装置、照射光学系および照射位置調整方法
US9513206B2 (en) 2013-03-29 2016-12-06 Sysmex Corporation Particle measuring apparatus
EP3278082B1 (en) 2015-04-02 2020-03-25 Particle Measuring Systems, Inc. Laser noise detection and mitigation in particle counting instruments
WO2017201451A1 (en) 2016-05-20 2017-11-23 Particle Measuring Systems, Inc. Automatic power control liquid particle counter with flow and bubble detection systems
US10197487B2 (en) 2016-06-03 2019-02-05 Particle Measuring Systems, Inc. Systems and methods for isolating condensate in a condensation particle counter
US11385161B2 (en) 2018-11-12 2022-07-12 Particle Measuring Systems, Inc. Calibration verification for optical particle analyzers
US11181455B2 (en) 2018-11-12 2021-11-23 Particle Measuring Systems, Inc. Calibration verification for optical particle analyzers
US11841311B2 (en) * 2018-11-19 2023-12-12 Samsung Electronics Co., Ltd. Multimodal dust sensor
CN110687022B (zh) * 2019-11-05 2021-09-24 珠海真理光学仪器有限公司 一种利用散射光的偏振差异测量颗粒折射率的方法及系统
WO2021247918A1 (en) * 2020-06-03 2021-12-09 Kinetic River Corp. Configurable particle analyzer apparatuses and methods

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US3835315A (en) * 1972-12-06 1974-09-10 Us Commerce System for determining parameters of a particle by radiant energy scattering techniques
US3851169A (en) * 1973-11-23 1974-11-26 Gen Motors Corp Apparatus for measuring aerosol particles
JPS5212585A (en) * 1975-07-21 1977-01-31 Fujitsu Ltd Semi_conductor device
JPS54114260A (en) * 1978-02-24 1979-09-06 Kyoto Giken Kk Measuring of microparticles within liquid
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US4667830A (en) * 1981-06-15 1987-05-26 The Board Of Trustees Of The Leland Stanford Junior University Method and means for sorting individual particles into containers for culturing, cloning, analysis, or the like
JPS58138063U (ja) * 1982-03-12 1983-09-17 リオン株式会社 光散乱微粒子計測装置
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4573796A (en) * 1984-01-06 1986-03-04 The United States Of America As Represented By The United States Department Of Energy Apparatus for eliminating background interference in fluorescence measurements
US4636075A (en) * 1984-08-22 1987-01-13 Particle Measuring Systems, Inc. Particle measurement utilizing orthogonally polarized components of a laser beam

Also Published As

Publication number Publication date
JPS6410150A (en) 1989-01-13
JP2642632B2 (ja) 1997-08-20
US4957363A (en) 1990-09-18
DE3822310A1 (de) 1989-01-12

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8128 New person/name/address of the agent

Representative=s name: STREHL, P., DIPL.-ING. DIPL.-WIRTSCH.-ING. SCHUEBE

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee