DE3789507T2 - Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. - Google Patents

Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden.

Info

Publication number
DE3789507T2
DE3789507T2 DE3789507T DE3789507T DE3789507T2 DE 3789507 T2 DE3789507 T2 DE 3789507T2 DE 3789507 T DE3789507 T DE 3789507T DE 3789507 T DE3789507 T DE 3789507T DE 3789507 T2 DE3789507 T2 DE 3789507T2
Authority
DE
Germany
Prior art keywords
polytetrapeptides
polypentapeptides
elastin
temperature
structural development
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3789507T
Other languages
English (en)
Other versions
DE3789507D1 (de
Inventor
Dan Urry
Kari Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Original Assignee
UAB Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation filed Critical UAB Research Foundation
Publication of DE3789507D1 publication Critical patent/DE3789507D1/de
Application granted granted Critical
Publication of DE3789507T2 publication Critical patent/DE3789507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2929—Bicomponent, conjugate, composite or collateral fibers or filaments [i.e., coextruded sheath-core or side-by-side type]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
DE3789507T 1986-08-27 1987-08-27 Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. Expired - Fee Related DE3789507T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/900,895 US4783523A (en) 1986-08-27 1986-08-27 Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides
PCT/US1987/002141 WO1988001623A1 (en) 1986-08-27 1987-08-27 Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides

Publications (2)

Publication Number Publication Date
DE3789507D1 DE3789507D1 (de) 1994-05-05
DE3789507T2 true DE3789507T2 (de) 1994-07-14

Family

ID=25413260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789507T Expired - Fee Related DE3789507T2 (de) 1986-08-27 1987-08-27 Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden.

Country Status (5)

Country Link
US (1) US4783523A (de)
EP (1) EP0321496B1 (de)
JP (1) JP2726420B2 (de)
DE (1) DE3789507T2 (de)
WO (1) WO1988001623A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064430A (en) * 1985-10-31 1991-11-12 Uab Research Foundation Polynonapeptide bioelastomers having an increased elastic modulus
US5336256A (en) * 1986-04-17 1994-08-09 Uab Research Foundation Elastomeric polypeptides as vascular prosthetic materials
US5606019A (en) 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
DE68918388T2 (de) * 1988-04-21 1995-03-02 Uab Research Foundation Bioelastomer ohne adhäsionseigenschaft zum einsatz am wundort.
US5226292A (en) * 1991-04-22 1993-07-13 Uab Research Foundation Polymers capable of baromechanical and barochemical transduction
SG93791A1 (en) 1992-12-22 2003-01-21 Univ Sydney Synthetic polynucleotides
US5726040A (en) * 1993-11-10 1998-03-10 Ensley; Burt D. Cosmetic compositions including tropoelastin isomorphs
US5527610A (en) * 1994-05-20 1996-06-18 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials
US6693072B2 (en) * 1994-06-02 2004-02-17 Aventis Pharmaceuticals Inc. Elastase inhibitors
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US7001328B1 (en) * 1994-11-15 2006-02-21 Kenton W. Gregory Method for using tropoelastin and for producing tropoelastin biomaterials
US6087552A (en) * 1994-11-15 2000-07-11 Sisters Of Providence Of Oregon Method of producing fused biomaterials and tissue
US6372228B1 (en) 1994-11-15 2002-04-16 Kenton W. Gregory Method of producing elastin, elastin-based biomaterials and tropoelastin materials
US5854387A (en) * 1995-04-14 1998-12-29 Bioelastics Research, Ltd. Simple method for the purification of a bioelastic polymer
US6004782A (en) * 1995-04-14 1999-12-21 Bioelastics Research Ltd. Hyperexpression of bioelastic polypeptides
US5972406A (en) * 1995-04-14 1999-10-26 Bioelastics Research Ltd. Bioelastomers suitable as food product additives
US6451326B2 (en) * 1996-05-02 2002-09-17 Burt D. Ensley Cosmetic compositions
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
WO1998005685A2 (en) * 1996-08-07 1998-02-12 Protein Specialties, Ltd. Self-aligning peptides derived from elastin and other fibrous proteins
US6127166A (en) * 1997-11-03 2000-10-03 Bayley; Hagan Molluscan ligament polypeptides and genes encoding them
US6113636A (en) * 1997-11-20 2000-09-05 St. Jude Medical, Inc. Medical article with adhered antimicrobial metal
CA2383539C (en) 1999-05-28 2007-12-04 Kenton W. Gregory Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue
WO2001049984A2 (en) * 1999-12-22 2001-07-12 Bioelastics Research, Ltd. Acoustic absorption polymers and their methods of use
US20050255554A1 (en) * 2000-03-20 2005-11-17 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
US6852834B2 (en) 2000-03-20 2005-02-08 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
AU2002350026A1 (en) 2001-11-01 2003-05-12 Lawrence M. Boyd System and method for the pretreatment of the endplates of an intervertebral disc
WO2003037166A2 (en) 2001-11-01 2003-05-08 Boyd Lawrence M Devices and methods for the restoration of a spinal disc
JP2008504895A (ja) 2004-06-29 2008-02-21 スパイン・ウェイブ・インコーポレーテッド 椎間板の欠陥及び損傷を治療する方法
US7305824B1 (en) * 2004-08-06 2007-12-11 Hrl Laboratories, Llc Power-off hold element
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8334257B2 (en) 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) * 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US7709227B2 (en) * 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
WO2008058323A1 (en) 2006-11-13 2008-05-22 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
WO2008140703A2 (en) * 2007-05-10 2008-11-20 Elastin Specialties, Inc. Synthetic peptide materials for joint reconstruction, repair and cushioning
EP3412300A1 (de) 2008-06-27 2018-12-12 Duke University Therapeutika mit elastinähnlichen peptiden
BR112012003327A2 (pt) * 2009-08-14 2017-06-06 Phasebio Pharmaceuticals Inc peptídeos intestinais vasoativos modificados
KR101245253B1 (ko) 2010-10-18 2013-03-25 재단법인대구경북과학기술원 이중 블럭 엘라스틴 단백질 및 그 유전자, 그 발현 벡터
JP6004415B2 (ja) * 2010-11-25 2016-10-05 国立大学法人九州工業大学 ペプチドおよびその自己集合方法、その集合体、これらを用いた細胞培養基材、並びに、細胞シートの製造方法
ES2669190T3 (es) 2011-06-06 2018-05-24 Phasebio Pharmaceuticals, Inc. Uso de péptidos intestinales vasoactivos modificados en el tratamiento de la hipertensión
AU2015255752B2 (en) 2014-05-08 2020-07-23 Immunoforge Co., Ltd. Methods and compositions for treating Cystic Fibrosis
US10688156B2 (en) 2015-02-09 2020-06-23 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132746A (en) * 1976-07-09 1979-01-02 University Of Alabama, Birmingham Medical & Education Foundation Synthetic elastomeric insoluble cross-linked polypentapeptide
US4474851A (en) * 1981-10-02 1984-10-02 The University Of Alabama In Birmingham Elastomeric composite material comprising a polypeptide
US4500700A (en) * 1981-10-02 1985-02-19 The Board Of Trustees Of The University Of Alabama For The University Of Alabama In Birmingham Elastomeric composite material comprising a polypentapeptide having an amino acid of opposite chirality in position three
US4589882A (en) * 1983-09-19 1986-05-20 Urry Dan W Enzymatically crosslinked bioelastomers

Also Published As

Publication number Publication date
EP0321496A4 (de) 1989-12-22
JPH01503714A (ja) 1989-12-14
EP0321496A1 (de) 1989-06-28
DE3789507D1 (de) 1994-05-05
JP2726420B2 (ja) 1998-03-11
EP0321496B1 (de) 1994-03-30
WO1988001623A1 (en) 1988-03-10
US4783523A (en) 1988-11-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee