DE3789507D1 - Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. - Google Patents

Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden.

Info

Publication number
DE3789507D1
DE3789507D1 DE87905993T DE3789507T DE3789507D1 DE 3789507 D1 DE3789507 D1 DE 3789507D1 DE 87905993 T DE87905993 T DE 87905993T DE 3789507 T DE3789507 T DE 3789507T DE 3789507 D1 DE3789507 D1 DE 3789507D1
Authority
DE
Germany
Prior art keywords
polytetrapeptides
polypentapeptides
elastin
temperature
structural development
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87905993T
Other languages
English (en)
Other versions
DE3789507T2 (de
Inventor
Dan Urry
Kari Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Original Assignee
UAB Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation filed Critical UAB Research Foundation
Application granted granted Critical
Publication of DE3789507D1 publication Critical patent/DE3789507D1/de
Publication of DE3789507T2 publication Critical patent/DE3789507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/29Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913Rod, strand, filament or fiber
    • Y10T428/2929Bicomponent, conjugate, composite or collateral fibers or filaments [i.e., coextruded sheath-core or side-by-side type]
DE3789507T 1986-08-27 1987-08-27 Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. Expired - Fee Related DE3789507T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/900,895 US4783523A (en) 1986-08-27 1986-08-27 Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides
PCT/US1987/002141 WO1988001623A1 (en) 1986-08-27 1987-08-27 Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides

Publications (2)

Publication Number Publication Date
DE3789507D1 true DE3789507D1 (de) 1994-05-05
DE3789507T2 DE3789507T2 (de) 1994-07-14

Family

ID=25413260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789507T Expired - Fee Related DE3789507T2 (de) 1986-08-27 1987-08-27 Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden.

Country Status (5)

Country Link
US (1) US4783523A (de)
EP (1) EP0321496B1 (de)
JP (1) JP2726420B2 (de)
DE (1) DE3789507T2 (de)
WO (1) WO1988001623A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064430A (en) * 1985-10-31 1991-11-12 Uab Research Foundation Polynonapeptide bioelastomers having an increased elastic modulus
US5336256A (en) * 1986-04-17 1994-08-09 Uab Research Foundation Elastomeric polypeptides as vascular prosthetic materials
US5606019A (en) * 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
JP2820750B2 (ja) * 1988-04-21 1998-11-05 ユーエービー リサーチ ファウンデイション 創傷治療部位における癒着の発生からの保護に適するバイオエラストマー材料
US5226292A (en) * 1991-04-22 1993-07-13 Uab Research Foundation Polymers capable of baromechanical and barochemical transduction
ATE412052T1 (de) 1992-12-22 2008-11-15 Univ Sydney Synthetische polynukleotide
US5726040A (en) * 1993-11-10 1998-03-10 Ensley; Burt D. Cosmetic compositions including tropoelastin isomorphs
US5527610A (en) * 1994-05-20 1996-06-18 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials
US6693072B2 (en) * 1994-06-02 2004-02-17 Aventis Pharmaceuticals Inc. Elastase inhibitors
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US7001328B1 (en) 1994-11-15 2006-02-21 Kenton W. Gregory Method for using tropoelastin and for producing tropoelastin biomaterials
US6372228B1 (en) 1994-11-15 2002-04-16 Kenton W. Gregory Method of producing elastin, elastin-based biomaterials and tropoelastin materials
US6087552A (en) * 1994-11-15 2000-07-11 Sisters Of Providence Of Oregon Method of producing fused biomaterials and tissue
US5854387A (en) * 1995-04-14 1998-12-29 Bioelastics Research, Ltd. Simple method for the purification of a bioelastic polymer
US6004782A (en) * 1995-04-14 1999-12-21 Bioelastics Research Ltd. Hyperexpression of bioelastic polypeptides
US5972406A (en) * 1995-04-14 1999-10-26 Bioelastics Research Ltd. Bioelastomers suitable as food product additives
US6451326B2 (en) * 1996-05-02 2002-09-17 Burt D. Ensley Cosmetic compositions
WO1998005685A2 (en) * 1996-08-07 1998-02-12 Protein Specialties, Ltd. Self-aligning peptides derived from elastin and other fibrous proteins
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
US6127166A (en) * 1997-11-03 2000-10-03 Bayley; Hagan Molluscan ligament polypeptides and genes encoding them
US6113636A (en) * 1997-11-20 2000-09-05 St. Jude Medical, Inc. Medical article with adhered antimicrobial metal
CA2383539C (en) 1999-05-28 2007-12-04 Kenton W. Gregory Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue
EP1246753A4 (de) * 1999-12-22 2005-02-02 Bioelastics Res Ltd Polymere zur schall-absorption und verfahren zu deren verwendung
US6852834B2 (en) 2000-03-20 2005-02-08 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
US20050255554A1 (en) * 2000-03-20 2005-11-17 Ashutosh Chilkoti Fusion peptides isolatable by phase transition
US7799833B2 (en) 2001-11-01 2010-09-21 Spine Wave, Inc. System and method for the pretreatment of the endplates of an intervertebral disc
AU2002336694A1 (en) * 2001-11-01 2003-05-12 Lawrence M. Boyd Devices and methods for the restoration of a spinal disc
US7837733B2 (en) 2004-06-29 2010-11-23 Spine Wave, Inc. Percutaneous methods for injecting a curable biomaterial into an intervertebral space
US7305824B1 (en) * 2004-08-06 2007-12-11 Hrl Laboratories, Llc Power-off hold element
WO2007073486A2 (en) 2005-12-20 2007-06-28 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US7709227B2 (en) * 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
WO2008058323A1 (en) 2006-11-13 2008-05-22 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
CA2686895A1 (en) * 2007-05-10 2008-11-20 Elastin Specialties, Inc. Synthetic peptide materials for joint reconstruction, repair and cushioning
EP2926825A1 (de) 2008-06-27 2015-10-07 Duke University Therapeutika mit elastinähnlichen peptiden
KR101887009B1 (ko) 2009-08-14 2018-08-09 파세비오 파마수티컬스 인코포레이티드 변형된 혈관활성 장 펩티드
KR101245253B1 (ko) 2010-10-18 2013-03-25 재단법인대구경북과학기술원 이중 블럭 엘라스틴 단백질 및 그 유전자, 그 발현 벡터
JP6004415B2 (ja) * 2010-11-25 2016-10-05 国立大学法人九州工業大学 ペプチドおよびその自己集合方法、その集合体、これらを用いた細胞培養基材、並びに、細胞シートの製造方法
US9561262B2 (en) 2011-06-06 2017-02-07 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
WO2015172046A1 (en) 2014-05-08 2015-11-12 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating cystic fibrosis
JP6824888B2 (ja) 2015-02-09 2021-02-03 フェーズバイオ ファーマシューティカルズ,インコーポレイテッド 筋肉の疾患および障害を治療するための方法および組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132746A (en) * 1976-07-09 1979-01-02 University Of Alabama, Birmingham Medical & Education Foundation Synthetic elastomeric insoluble cross-linked polypentapeptide
US4500700A (en) * 1981-10-02 1985-02-19 The Board Of Trustees Of The University Of Alabama For The University Of Alabama In Birmingham Elastomeric composite material comprising a polypentapeptide having an amino acid of opposite chirality in position three
US4474851A (en) * 1981-10-02 1984-10-02 The University Of Alabama In Birmingham Elastomeric composite material comprising a polypeptide
US4589882A (en) * 1983-09-19 1986-05-20 Urry Dan W Enzymatically crosslinked bioelastomers

Also Published As

Publication number Publication date
DE3789507T2 (de) 1994-07-14
US4783523A (en) 1988-11-08
EP0321496B1 (de) 1994-03-30
JPH01503714A (ja) 1989-12-14
WO1988001623A1 (en) 1988-03-10
JP2726420B2 (ja) 1998-03-11
EP0321496A4 (de) 1989-12-22
EP0321496A1 (de) 1989-06-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee