DE3789507D1 - Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. - Google Patents
Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden.Info
- Publication number
- DE3789507D1 DE3789507D1 DE87905993T DE3789507T DE3789507D1 DE 3789507 D1 DE3789507 D1 DE 3789507D1 DE 87905993 T DE87905993 T DE 87905993T DE 3789507 T DE3789507 T DE 3789507T DE 3789507 D1 DE3789507 D1 DE 3789507D1
- Authority
- DE
- Germany
- Prior art keywords
- polytetrapeptides
- polypentapeptides
- elastin
- temperature
- structural development
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y10T428/2929—Bicomponent, conjugate, composite or collateral fibers or filaments [i.e., coextruded sheath-core or side-by-side type]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/900,895 US4783523A (en) | 1986-08-27 | 1986-08-27 | Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides |
PCT/US1987/002141 WO1988001623A1 (en) | 1986-08-27 | 1987-08-27 | Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3789507D1 true DE3789507D1 (de) | 1994-05-05 |
DE3789507T2 DE3789507T2 (de) | 1994-07-14 |
Family
ID=25413260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3789507T Expired - Fee Related DE3789507T2 (de) | 1986-08-27 | 1987-08-27 | Temperaturabhängige kraft- und strukturentwicklung von elastin polytetrapeptiden und polypentapeptiden. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4783523A (de) |
EP (1) | EP0321496B1 (de) |
JP (1) | JP2726420B2 (de) |
DE (1) | DE3789507T2 (de) |
WO (1) | WO1988001623A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5064430A (en) * | 1985-10-31 | 1991-11-12 | Uab Research Foundation | Polynonapeptide bioelastomers having an increased elastic modulus |
US5336256A (en) * | 1986-04-17 | 1994-08-09 | Uab Research Foundation | Elastomeric polypeptides as vascular prosthetic materials |
US5606019A (en) * | 1987-10-29 | 1997-02-25 | Protien Polymer Technologies, Inc. | Synthetic protein as implantables |
JP2820750B2 (ja) * | 1988-04-21 | 1998-11-05 | ユーエービー リサーチ ファウンデイション | 創傷治療部位における癒着の発生からの保護に適するバイオエラストマー材料 |
US5226292A (en) * | 1991-04-22 | 1993-07-13 | Uab Research Foundation | Polymers capable of baromechanical and barochemical transduction |
ATE412052T1 (de) | 1992-12-22 | 2008-11-15 | Univ Sydney | Synthetische polynukleotide |
US5726040A (en) * | 1993-11-10 | 1998-03-10 | Ensley; Burt D. | Cosmetic compositions including tropoelastin isomorphs |
US5527610A (en) * | 1994-05-20 | 1996-06-18 | The Uab Research Foundation | Elastomeric polypeptide matrices for preventing adhesion of biological materials |
US6693072B2 (en) * | 1994-06-02 | 2004-02-17 | Aventis Pharmaceuticals Inc. | Elastase inhibitors |
US5989244A (en) * | 1994-11-15 | 1999-11-23 | Gregory; Kenton W. | Method of use of a sheet of elastin or elastin-based material |
US7001328B1 (en) | 1994-11-15 | 2006-02-21 | Kenton W. Gregory | Method for using tropoelastin and for producing tropoelastin biomaterials |
US6372228B1 (en) | 1994-11-15 | 2002-04-16 | Kenton W. Gregory | Method of producing elastin, elastin-based biomaterials and tropoelastin materials |
US6087552A (en) * | 1994-11-15 | 2000-07-11 | Sisters Of Providence Of Oregon | Method of producing fused biomaterials and tissue |
US5854387A (en) * | 1995-04-14 | 1998-12-29 | Bioelastics Research, Ltd. | Simple method for the purification of a bioelastic polymer |
US6004782A (en) * | 1995-04-14 | 1999-12-21 | Bioelastics Research Ltd. | Hyperexpression of bioelastic polypeptides |
US5972406A (en) * | 1995-04-14 | 1999-10-26 | Bioelastics Research Ltd. | Bioelastomers suitable as food product additives |
US6451326B2 (en) * | 1996-05-02 | 2002-09-17 | Burt D. Ensley | Cosmetic compositions |
WO1998005685A2 (en) * | 1996-08-07 | 1998-02-12 | Protein Specialties, Ltd. | Self-aligning peptides derived from elastin and other fibrous proteins |
US6489446B1 (en) | 1996-08-07 | 2002-12-03 | Hsc Research And Development Limited Partnership | Self-aligning peptides modeled on human elastin and other fibrous proteins |
US6127166A (en) * | 1997-11-03 | 2000-10-03 | Bayley; Hagan | Molluscan ligament polypeptides and genes encoding them |
US6113636A (en) * | 1997-11-20 | 2000-09-05 | St. Jude Medical, Inc. | Medical article with adhered antimicrobial metal |
CA2383539C (en) | 1999-05-28 | 2007-12-04 | Kenton W. Gregory | Methods for producing laminated elastin, elastin-based materials and tropoelastin products for repairing and/or replacing tissue |
EP1246753A4 (de) * | 1999-12-22 | 2005-02-02 | Bioelastics Res Ltd | Polymere zur schall-absorption und verfahren zu deren verwendung |
US6852834B2 (en) | 2000-03-20 | 2005-02-08 | Ashutosh Chilkoti | Fusion peptides isolatable by phase transition |
US20050255554A1 (en) * | 2000-03-20 | 2005-11-17 | Ashutosh Chilkoti | Fusion peptides isolatable by phase transition |
US7799833B2 (en) | 2001-11-01 | 2010-09-21 | Spine Wave, Inc. | System and method for the pretreatment of the endplates of an intervertebral disc |
AU2002336694A1 (en) * | 2001-11-01 | 2003-05-12 | Lawrence M. Boyd | Devices and methods for the restoration of a spinal disc |
US7837733B2 (en) | 2004-06-29 | 2010-11-23 | Spine Wave, Inc. | Percutaneous methods for injecting a curable biomaterial into an intervertebral space |
US7305824B1 (en) * | 2004-08-06 | 2007-12-11 | Hrl Laboratories, Llc | Power-off hold element |
WO2007073486A2 (en) | 2005-12-20 | 2007-06-28 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
US8841255B2 (en) | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
US7709227B2 (en) * | 2006-01-04 | 2010-05-04 | Phasebio Pharmaceuticals, Inc. | Multimeric ELP fusion constructs |
WO2008058323A1 (en) | 2006-11-13 | 2008-05-22 | The University Of Sydney | Use of tropoelastin for repair or restoration of tissue |
CA2686895A1 (en) * | 2007-05-10 | 2008-11-20 | Elastin Specialties, Inc. | Synthetic peptide materials for joint reconstruction, repair and cushioning |
EP2926825A1 (de) | 2008-06-27 | 2015-10-07 | Duke University | Therapeutika mit elastinähnlichen peptiden |
KR101887009B1 (ko) | 2009-08-14 | 2018-08-09 | 파세비오 파마수티컬스 인코포레이티드 | 변형된 혈관활성 장 펩티드 |
KR101245253B1 (ko) | 2010-10-18 | 2013-03-25 | 재단법인대구경북과학기술원 | 이중 블럭 엘라스틴 단백질 및 그 유전자, 그 발현 벡터 |
JP6004415B2 (ja) * | 2010-11-25 | 2016-10-05 | 国立大学法人九州工業大学 | ペプチドおよびその自己集合方法、その集合体、これらを用いた細胞培養基材、並びに、細胞シートの製造方法 |
US9561262B2 (en) | 2011-06-06 | 2017-02-07 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
WO2015172046A1 (en) | 2014-05-08 | 2015-11-12 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating cystic fibrosis |
JP6824888B2 (ja) | 2015-02-09 | 2021-02-03 | フェーズバイオ ファーマシューティカルズ,インコーポレイテッド | 筋肉の疾患および障害を治療するための方法および組成物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4132746A (en) * | 1976-07-09 | 1979-01-02 | University Of Alabama, Birmingham Medical & Education Foundation | Synthetic elastomeric insoluble cross-linked polypentapeptide |
US4500700A (en) * | 1981-10-02 | 1985-02-19 | The Board Of Trustees Of The University Of Alabama For The University Of Alabama In Birmingham | Elastomeric composite material comprising a polypentapeptide having an amino acid of opposite chirality in position three |
US4474851A (en) * | 1981-10-02 | 1984-10-02 | The University Of Alabama In Birmingham | Elastomeric composite material comprising a polypeptide |
US4589882A (en) * | 1983-09-19 | 1986-05-20 | Urry Dan W | Enzymatically crosslinked bioelastomers |
-
1986
- 1986-08-27 US US06/900,895 patent/US4783523A/en not_active Expired - Lifetime
-
1987
- 1987-08-27 WO PCT/US1987/002141 patent/WO1988001623A1/en active IP Right Grant
- 1987-08-27 JP JP62505482A patent/JP2726420B2/ja not_active Expired - Fee Related
- 1987-08-27 EP EP87905993A patent/EP0321496B1/de not_active Expired - Lifetime
- 1987-08-27 DE DE3789507T patent/DE3789507T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3789507T2 (de) | 1994-07-14 |
US4783523A (en) | 1988-11-08 |
EP0321496B1 (de) | 1994-03-30 |
JPH01503714A (ja) | 1989-12-14 |
WO1988001623A1 (en) | 1988-03-10 |
JP2726420B2 (ja) | 1998-03-11 |
EP0321496A4 (de) | 1989-12-22 |
EP0321496A1 (de) | 1989-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |