DE3783928T2 - Verfahren zur immunoassay. - Google Patents

Verfahren zur immunoassay.

Info

Publication number
DE3783928T2
DE3783928T2 DE8787302427T DE3783928T DE3783928T2 DE 3783928 T2 DE3783928 T2 DE 3783928T2 DE 8787302427 T DE8787302427 T DE 8787302427T DE 3783928 T DE3783928 T DE 3783928T DE 3783928 T2 DE3783928 T2 DE 3783928T2
Authority
DE
Germany
Prior art keywords
reagent
analyte
ligand
galactosidase
diethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787302427T
Other languages
German (de)
English (en)
Other versions
DE3783928D1 (de
Inventor
Gerald John Allen
Roger David Philo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biochem Immunosystems (ndgesd Staates D LLC
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Publication of DE3783928D1 publication Critical patent/DE3783928D1/de
Application granted granted Critical
Publication of DE3783928T2 publication Critical patent/DE3783928T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548Carbohydrates, e.g. dextran
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/973Simultaneous determination of more than one analyte
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
DE8787302427T 1986-03-21 1987-03-20 Verfahren zur immunoassay. Expired - Fee Related DE3783928T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607101A GB8607101D0 (en) 1986-03-21 1986-03-21 Immunoassay

Publications (2)

Publication Number Publication Date
DE3783928D1 DE3783928D1 (de) 1993-03-18
DE3783928T2 true DE3783928T2 (de) 1993-07-15

Family

ID=10595042

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787302427T Expired - Fee Related DE3783928T2 (de) 1986-03-21 1987-03-20 Verfahren zur immunoassay.

Country Status (8)

Country Link
US (1) US5108896A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0238353B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS62284262A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE85434T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3783928T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2053532T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB8607101D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3007359T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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WO1988005536A1 (en) * 1987-01-20 1988-07-28 Interferon Sciences, Inc. Multicolour western blot
GB8801199D0 (en) * 1988-01-20 1988-02-17 Iq Bio Ltd Dual enzyme assay
DE3822750A1 (de) * 1988-07-05 1990-01-11 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
KR900702371A (ko) * 1988-10-14 1990-12-06 비로발 에스. 아. 다른 종류의 항체 및/또는 항원을 동시에 검출하는 방법
EP0470966B1 (en) * 1989-03-21 1996-06-05 Hygeia Sciences, Inc. Simultaneous dual analyte assay
EP0479929B1 (en) * 1989-06-26 1994-04-13 Tritech Partners Vitamin b12 assay
US5064770A (en) * 1989-08-01 1991-11-12 Wisconsin Alumni Research Foundation Assay for 1,25-dihydroxy vitamin d receptor protein
ATE200709T1 (de) * 1992-02-24 2001-05-15 Genelabs Tech Inc Htlv-i/htlv-ii assay und verfahren
GB9302983D0 (en) * 1993-02-15 1993-03-31 Univ London One-pot assay
ATE340866T1 (de) * 1994-10-28 2006-10-15 Gen Probe Inc Zusammensetzungen und verfahren für die gleichzeitige detektion und quantifizierung von einer mehrheit spezifischer nuklein säure sequenzen
WO1996019731A2 (en) * 1994-12-22 1996-06-27 Abbott Laboratories Differential timing method for detecting multiple analytes in a test sample
IT1273506B (it) * 1995-04-06 1997-07-08 Scient Marketing Service S R L Test diagnostico per il rilevamento rapido e sicuro di un marcatore clinico per la diagnosi di menopausa nella donna
US5935796A (en) * 1995-06-30 1999-08-10 The University Of Melbourne Diagnostic methods and compositions relating to the proteoglycan proteins of cartilage breakdown
DE19632156C1 (de) * 1996-08-09 1998-01-08 Univ Eberhard Karls Verfahren zur Detektion mehrerer Antigene auf biologischem Material
US5902727A (en) * 1996-09-04 1999-05-11 Washington University Method for localization and quantitation of a substance in a biological sample
TW591230B (en) * 1997-10-14 2004-06-11 Bayer Ag Method for improving the accuracy of the semi-quantitative determination of analyte in fluid samples
CA2316130A1 (en) * 1999-08-19 2001-02-19 Masanori Fukui Method for detection or determination of hcv core antigens and reagent for detection or determination for use therein
US7402397B2 (en) 2002-05-21 2008-07-22 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
US20040229294A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
US20040229380A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
US20040018577A1 (en) * 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
WO2005017485A2 (en) * 2003-05-22 2005-02-24 Agdia, Inc. Multiplex enzyme-linked immunosorbent assay for detecting multiple analytes
US7402399B2 (en) * 2003-10-14 2008-07-22 Monogram Biosciences, Inc. Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy
US20050186642A1 (en) * 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
US7921603B2 (en) * 2004-09-09 2011-04-12 Duane Darnell Systems for a fire-resistant door jamb
AU2008207746B2 (en) 2007-01-26 2013-09-05 University Of Louisville Research Foundation, Inc. Methods of detecting autoantibodies for diagnosing and characterizing disorders
RU2339953C1 (ru) * 2007-06-13 2008-11-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт биологического приборостроения" (ФГУП "ГосНИИ БП") Способ многоаналитного иммуноанализа с использованием микрочастиц
US20100330592A1 (en) * 2008-01-29 2010-12-30 Key Marc E Method for detecting truncated molecules
RU2379691C1 (ru) * 2008-07-07 2010-01-20 Закрытое акционерное общество "ИММУНОСКРИН" (ЗАО "ИММУНОСКРИН") Способ многоаналитного иммуноанализа с использованием микрочастиц
EP3865567A1 (en) 2010-08-26 2021-08-18 Charm Sciences Inc. Lateral flow assay analysis
WO2012154983A2 (en) 2011-05-10 2012-11-15 Biocare Medical, Llc Systems and methods for anti-pax8 antibodies
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
ES2682345T3 (es) 2012-09-27 2018-09-20 Biocare Medical, Llc Sistemas y procedimientos de anticuerpos antiuroplaquina II
WO2014100220A2 (en) 2012-12-18 2014-06-26 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
WO2014134587A1 (en) 2013-02-28 2014-09-04 Biocare Medical, Llc Anti-p40 antibodies systems and methods
ES2765423T3 (es) 2013-10-03 2020-06-09 Biocare Medical Llc Sistemas y procedimientos de anticuerpos anti-SOX10
WO2015200210A1 (en) * 2014-06-23 2015-12-30 Advanced Animal Diagnostics, Inc. Apparatus for use in a magnetic system for the rapid detection or separation of targets of interest in liquid samples
CN108700579B (zh) 2016-12-28 2021-10-08 纽勤有限公司 器具分析装置和使用所述装置的方法
WO2020206175A1 (en) * 2019-04-03 2020-10-08 Access Medical Systems, Ltd. Method for re-using hapten-coated probe in an immunoassay

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ZA756003B (en) * 1975-09-22 1977-04-27 Chembro Holdings Pty Ltd Measurement of alkaline phophatase levels in body fluids
GB2057685B (en) * 1979-03-19 1983-12-21 Int Diagnostic Tech Double tagged immunoassay
CA1148859A (en) * 1979-06-14 1983-06-28 Lacy R. Overby Simultaneous assay of two hepatitis viruses using a solid phase
JPS5745454A (en) * 1980-09-02 1982-03-15 Fuji Photo Film Co Ltd Immunochemical measuring method for various minor components
EP0105714B1 (en) * 1982-09-29 1988-07-27 Serono Diagnostics Limited Immunoassay of antigens
US4599307A (en) * 1983-07-18 1986-07-08 Becton, Dickinson And Company Method for elimination of selected cell populations in analytic cytology
DE3400027A1 (de) * 1984-01-02 1985-07-18 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung eines polyvalenten antigens und reagenz hierfuer
US4690890A (en) * 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
GB8422452D0 (en) * 1984-09-05 1984-10-10 Serono Diagnostics Ltd Assay
GB8501671D0 (en) * 1985-01-23 1985-02-27 Allen G J Immunoassay

Also Published As

Publication number Publication date
US5108896A (en) 1992-04-28
GB8607101D0 (en) 1986-04-30
DE3783928D1 (de) 1993-03-18
EP0238353B1 (en) 1993-02-03
GR3007359T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-07-30
JPS62284262A (ja) 1987-12-10
EP0238353A3 (en) 1989-11-15
ATE85434T1 (de) 1993-02-15
ES2053532T3 (es) 1994-08-01
EP0238353A2 (en) 1987-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIOCHEM IMMUNOSYSTEMS L.L.C. (N.D.GES.D. STAATES D

8339 Ceased/non-payment of the annual fee