DE3774024D1 - Chemisches verfahren. - Google Patents

Chemisches verfahren.

Info

Publication number
DE3774024D1
DE3774024D1 DE8787306730T DE3774024T DE3774024D1 DE 3774024 D1 DE3774024 D1 DE 3774024D1 DE 8787306730 T DE8787306730 T DE 8787306730T DE 3774024 T DE3774024 T DE 3774024T DE 3774024 D1 DE3774024 D1 DE 3774024D1
Authority
DE
Germany
Prior art keywords
chemical process
cimetidine
precipitation
conducted
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787306730T
Other languages
English (en)
Inventor
Harold Graboyes
David Samuel Kirkpatrick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
SmithKline Beecham Corp
Original Assignee
GlaxoSmithKline LLC
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline LLC, SmithKline Beecham Corp filed Critical GlaxoSmithKline LLC
Application granted granted Critical
Publication of DE3774024D1 publication Critical patent/DE3774024D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Cephalosporin Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DE8787306730T 1986-08-01 1987-07-29 Chemisches verfahren. Expired - Lifetime DE3774024D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868618846A GB8618846D0 (en) 1986-08-01 1986-08-01 Chemical process

Publications (1)

Publication Number Publication Date
DE3774024D1 true DE3774024D1 (de) 1991-11-28

Family

ID=10602096

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787306730T Expired - Lifetime DE3774024D1 (de) 1986-08-01 1987-07-29 Chemisches verfahren.

Country Status (19)

Country Link
US (1) US4786735A (de)
EP (1) EP0255376B1 (de)
JP (1) JPH0762002B2 (de)
KR (1) KR880002838A (de)
CN (1) CN87105393A (de)
AT (1) ATE68791T1 (de)
AU (1) AU604733B2 (de)
CA (1) CA1301767C (de)
CZ (1) CZ397491A3 (de)
DE (1) DE3774024D1 (de)
DK (1) DK163303C (de)
ES (1) ES2025665T3 (de)
FI (1) FI94633C (de)
GB (1) GB8618846D0 (de)
GR (1) GR3003253T3 (de)
IE (1) IE60415B1 (de)
NO (1) NO170975C (de)
PT (1) PT85435B (de)
ZA (1) ZA875675B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH064601B2 (ja) * 1987-11-04 1994-01-19 三井石油化学工業株式会社 N−シアノ−n’−メチル−n’’−[2−{(5−メチル−1h−イミダゾール−4−イル)メチルチオ}エチルグアニジンの精製法
JPH07110514B2 (ja) * 1990-06-25 1995-11-29 積水化学工業株式会社 芯材強化樹脂軒樋の製造方法
US5808090A (en) * 1996-02-22 1998-09-15 Endo Pharmaceuticals Inc. Process for preventing precipitation in cimetidine injection solutions
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
SK287354B6 (sk) * 2001-03-23 2010-08-09 Richter Gedeon Vegy�Szeti Gy�R Rt. Spôsob prípravy monohydrátu a kryštalických modifikácií flukonazolu
WO2003026611A2 (en) 2001-09-26 2003-04-03 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
DE10349113A1 (de) 2003-10-17 2005-05-12 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Aminocrotonylverbindungen
US7741358B2 (en) * 2005-04-14 2010-06-22 N.V. Organon Crystal form of asenapine maleate
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1543238A (en) * 1976-09-21 1979-03-28 Smith Kline French Lab Polymorph of cimetidine
JPS56104868A (en) * 1980-01-24 1981-08-20 Fujimoto Seiyaku Kk Conversion between polymorphous crystals of cimetidine
FI63753C (fi) * 1980-08-21 1987-02-19 Orion Yhtymae Oy Foerfarande foer framstaellning av kristallint simetidin.
HU185457B (en) * 1981-09-25 1985-02-28 Richter Gedeon Vegyeszet Process for preparating cimetidine-z
JPS58152868A (ja) * 1982-03-05 1983-09-10 Fujimoto Seiyaku Kk シメチジン1塩酸塩多形体およびその製造方法
IE55946B1 (en) * 1982-10-08 1991-02-27 Gea Farmaceutisk Fabrik As Thioethercyanoguanidines and their use as intermediates in producing imidazoles

Also Published As

Publication number Publication date
IE60415B1 (en) 1994-07-13
DK393087D0 (da) 1987-07-28
JPH0762002B2 (ja) 1995-07-05
FI94633C (fi) 1995-10-10
AU604733B2 (en) 1991-01-03
PT85435B (pt) 1990-06-29
EP0255376A1 (de) 1988-02-03
FI873340A (fi) 1988-02-02
FI873340A0 (fi) 1987-07-31
JPS6341465A (ja) 1988-02-22
DK163303C (da) 1992-07-06
CA1301767C (en) 1992-05-26
GR3003253T3 (en) 1993-02-17
CZ397491A3 (en) 1993-08-11
FI94633B (fi) 1995-06-30
DK163303B (da) 1992-02-17
US4786735A (en) 1988-11-22
CN87105393A (zh) 1988-02-17
ZA875675B (en) 1988-11-30
AU7625387A (en) 1988-02-04
KR880002838A (ko) 1988-05-11
NO170975C (no) 1993-01-06
EP0255376B1 (de) 1991-10-23
GB8618846D0 (en) 1986-09-10
NO873209L (no) 1988-02-02
NO873209D0 (no) 1987-07-31
NO170975B (no) 1992-09-28
PT85435A (en) 1987-08-01
DK393087A (da) 1988-02-02
IE872022L (en) 1988-02-01
ATE68791T1 (de) 1991-11-15
ES2025665T3 (es) 1992-04-01

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