DE3738721C2 - Immobilisierte Antikörper - Google Patents

Immobilisierte Antikörper

Info

Publication number
DE3738721C2
DE3738721C2 DE3738721A DE3738721A DE3738721C2 DE 3738721 C2 DE3738721 C2 DE 3738721C2 DE 3738721 A DE3738721 A DE 3738721A DE 3738721 A DE3738721 A DE 3738721A DE 3738721 C2 DE3738721 C2 DE 3738721C2
Authority
DE
Germany
Prior art keywords
antibodies
matrix polymer
immobilized
antibody
bifunctional reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3738721A
Other languages
German (de)
English (en)
Other versions
DE3738721A1 (de
Inventor
Beka Dr Solomon
Eran Dr Hadas
Gideon Dr Fleminger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm GmbH Darmstadt
Original Assignee
Roehm GmbH Darmstadt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm GmbH Darmstadt filed Critical Roehm GmbH Darmstadt
Priority to DE3738721A priority Critical patent/DE3738721C2/de
Priority to IL87550A priority patent/IL87550A0/xx
Priority to NL8802236A priority patent/NL8802236A/nl
Priority to FR888814546A priority patent/FR2623193B1/fr
Priority to GB8826392A priority patent/GB2212500B/en
Priority to SE8804100A priority patent/SE8804100L/xx
Priority to US07/270,280 priority patent/US4948836A/en
Priority to DK635388A priority patent/DK635388A/da
Priority to CH4207/88A priority patent/CH677363A5/de
Priority to JP63285945A priority patent/JPH01165600A/ja
Publication of DE3738721A1 publication Critical patent/DE3738721A1/de
Application granted granted Critical
Publication of DE3738721C2 publication Critical patent/DE3738721C2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548Carbohydrates, e.g. dextran
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer
    • Y10S530/816Attached to the carrier via a bridging agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE3738721A 1987-11-14 1987-11-14 Immobilisierte Antikörper Expired - Fee Related DE3738721C2 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE3738721A DE3738721C2 (de) 1987-11-14 1987-11-14 Immobilisierte Antikörper
IL87550A IL87550A0 (en) 1987-11-14 1988-08-24 Immobilized antibodies and their production
NL8802236A NL8802236A (nl) 1987-11-14 1988-09-12 Geimmobiliseerde antilichamen, alsmede werkwijzen ter bereiding ervan.
FR888814546A FR2623193B1 (fr) 1987-11-14 1988-11-08 Anticorps immobilises, fixes par liaison covalente a un polymere-matrice, et leur procede de preparation
GB8826392A GB2212500B (en) 1987-11-14 1988-11-11 Immobilized antibodies
US07/270,280 US4948836A (en) 1987-11-14 1988-11-14 Immobilized antibodies
SE8804100A SE8804100L (sv) 1987-11-14 1988-11-14 Immobiliserade via sitt modifierade kolhydratomraade kovalent till en matrispolymer bundna antikroppar
DK635388A DK635388A (da) 1987-11-14 1988-11-14 Immobiliserede antistoffer
CH4207/88A CH677363A5 (enExample) 1987-11-14 1988-11-14
JP63285945A JPH01165600A (ja) 1987-11-14 1988-11-14 固定化抗体およびその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3738721A DE3738721C2 (de) 1987-11-14 1987-11-14 Immobilisierte Antikörper

Publications (2)

Publication Number Publication Date
DE3738721A1 DE3738721A1 (de) 1989-05-24
DE3738721C2 true DE3738721C2 (de) 1995-10-05

Family

ID=6340504

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3738721A Expired - Fee Related DE3738721C2 (de) 1987-11-14 1987-11-14 Immobilisierte Antikörper

Country Status (10)

Country Link
US (1) US4948836A (enExample)
JP (1) JPH01165600A (enExample)
CH (1) CH677363A5 (enExample)
DE (1) DE3738721C2 (enExample)
DK (1) DK635388A (enExample)
FR (1) FR2623193B1 (enExample)
GB (1) GB2212500B (enExample)
IL (1) IL87550A0 (enExample)
NL (1) NL8802236A (enExample)
SE (1) SE8804100L (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3909456A1 (de) * 1989-03-22 1990-09-27 Roehm Gmbh Verbessertes verfahren zur herstellung immobilisierter antikoerper
DE4005927A1 (de) * 1990-02-25 1991-08-29 Roehm Gmbh Immobilisierung von proteinen an traegern
US5082929A (en) * 1990-08-08 1992-01-21 Bioprobe International, Inc. Immobilization of glycocompounds and glycoconjugates
CA2167931A1 (en) * 1993-08-27 1995-03-02 Edward N. Granados Hydrazine derivatized cells
JPH11503005A (ja) * 1995-03-08 1999-03-23 アクゾ ノーベル ナムローゼ フェンノートシャップ 表面修飾されたアフィニティ分離膜
US6509104B2 (en) 2000-12-05 2003-01-21 Michigan Biotechnology Institute Antithrombogenic polymer coating
TW200307734A (en) 2002-03-20 2003-12-16 Michigan Biotech Inst Conductive polymer-based material
DE102010038330A1 (de) 2010-07-23 2012-03-01 Aj Innuscreen Gmbh Verfahren, Vorrichtung und Testkit für Molekularbiologische Reaktionen
TWI799441B (zh) * 2017-08-23 2023-04-21 日商Jsr股份有限公司 層析用載體﹑配位子固定載體﹑層析管柱﹑標的物質之純化方法,及層析用載體之製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
US4210723A (en) * 1976-07-23 1980-07-01 The Dow Chemical Company Method of coupling a protein to an epoxylated latex
US4208309A (en) * 1977-05-20 1980-06-17 Rohm Gmbh Pearl polymer containing hollow pearls
DE3106456A1 (de) * 1981-02-21 1982-10-07 Röhm GmbH, 6100 Darmstadt Verfahren zur herstellung von perlfoermigen, hydrophilen, gegenueber proteinen bindungsaktiven traegerpolymeren
JPS5853757A (ja) * 1981-09-25 1983-03-30 Denki Kagaku Kogyo Kk 免疫アフイニテイクロマトグラフイ−用吸着体及びその製法
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4889916A (en) * 1985-11-19 1989-12-26 The Johns Hopkins University Protein label and drug delivery system
US4874813A (en) * 1987-02-09 1989-10-17 Shannessy Daniel J O Proteins bound to a marker or solid phase support matrix using a hydrazone linkage

Also Published As

Publication number Publication date
IL87550A0 (en) 1989-01-31
NL8802236A (nl) 1989-06-01
GB8826392D0 (en) 1988-12-14
DE3738721A1 (de) 1989-05-24
GB2212500B (en) 1992-01-22
FR2623193B1 (fr) 1994-10-14
CH677363A5 (enExample) 1991-05-15
GB2212500A (en) 1989-07-26
US4948836A (en) 1990-08-14
SE8804100L (sv) 1989-05-15
SE8804100D0 (sv) 1988-11-14
DK635388D0 (da) 1988-11-14
FR2623193A1 (fr) 1989-05-19
JPH01165600A (ja) 1989-06-29
DK635388A (da) 1989-05-15

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee