DE69429345T2 - Überzug für hydrophobe oberflächen um diese proteinresistent zu machen unter ermöglichung der kovalenten bindung spezifischer liganden - Google Patents

Überzug für hydrophobe oberflächen um diese proteinresistent zu machen unter ermöglichung der kovalenten bindung spezifischer liganden

Info

Publication number
DE69429345T2
DE69429345T2 DE69429345T DE69429345T DE69429345T2 DE 69429345 T2 DE69429345 T2 DE 69429345T2 DE 69429345 T DE69429345 T DE 69429345T DE 69429345 T DE69429345 T DE 69429345T DE 69429345 T2 DE69429345 T2 DE 69429345T2
Authority
DE
Germany
Prior art keywords
protein
resistant
allowing
coating
make
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69429345T
Other languages
English (en)
Other versions
DE69429345D1 (de
Inventor
Maria Caldwell
Jan Carlsson
Jeng-Thun Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah
Original Assignee
University of Utah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah filed Critical University of Utah
Publication of DE69429345D1 publication Critical patent/DE69429345D1/de
Application granted granted Critical
Publication of DE69429345T2 publication Critical patent/DE69429345T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02—Compounds containing any of the groups, e.g. carbazates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
DE69429345T 1993-08-20 1994-08-22 Überzug für hydrophobe oberflächen um diese proteinresistent zu machen unter ermöglichung der kovalenten bindung spezifischer liganden Expired - Lifetime DE69429345T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/110,169 US5516703A (en) 1993-08-20 1993-08-20 Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
PCT/US1994/009480 WO1995006251A1 (en) 1993-08-20 1994-08-22 Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands

Publications (2)

Publication Number Publication Date
DE69429345D1 DE69429345D1 (de) 2002-01-17
DE69429345T2 true DE69429345T2 (de) 2002-08-14

Family

ID=22331580

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429345T Expired - Lifetime DE69429345T2 (de) 1993-08-20 1994-08-22 Überzug für hydrophobe oberflächen um diese proteinresistent zu machen unter ermöglichung der kovalenten bindung spezifischer liganden

Country Status (5)

Country Link
US (2) US5516703A (de)
EP (1) EP0701697B1 (de)
CA (1) CA2163519C (de)
DE (1) DE69429345T2 (de)
WO (1) WO1995006251A1 (de)

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US5874165A (en) * 1996-06-03 1999-02-23 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto polymeric subtrates
US5681754A (en) * 1996-06-07 1997-10-28 Abbott Laboratories Method for improving the performance of an immunoreagent in an immunoassay
US6093559A (en) 1996-10-24 2000-07-25 Corning Incorporated Producing low binding hydrophobic surfaces by treating with a low HLB number non-ionic surfactant
US6235541B1 (en) 1997-03-13 2001-05-22 The United States Of America As Represented By The Secretary Of The Navy Patterning antibodies on a surface
US5858801A (en) * 1997-03-13 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Patterning antibodies on a surface
DE19748489A1 (de) * 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
US6087452A (en) * 1998-06-02 2000-07-11 University Of Utah Metal-chelating surfacant
WO1999064849A1 (fr) * 1998-06-05 1999-12-16 Kyoto Daiichi Kagaku Co., Ltd. Appareil de mesure de l'activite ionique
US6706161B1 (en) * 1998-06-10 2004-03-16 Agilent Technologies, Inc. Methods and compositions for modifying the surface of a polymeric substrate
US7138254B2 (en) 1999-08-02 2006-11-21 Ge Healthcare (Sv) Corp. Methods and apparatus for performing submicroliter reactions with nucleic acids or proteins
US6319674B1 (en) 1999-09-16 2001-11-20 Agilent Technologies, Inc. Methods for attaching substances to surfaces
DK1362240T3 (da) * 2000-10-10 2007-01-29 Serono Genetics Inst Sa Overfladeadsorberende polymerer og anvendelserne deraf til behandling af hydrofobe og hydrofile overflader
SE0004532D0 (sv) * 2000-12-07 2000-12-07 Caldwell Karin Dahlgren Use of mucin
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
CA2435894C (en) * 2001-02-02 2014-05-13 Allvivo, Inc. End group activated polymers with oligonucleotide ligands
US7501157B2 (en) * 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US20030148017A1 (en) * 2001-12-07 2003-08-07 Olli Tuominen Copolymer coating for a hydrophobic membrane
DE10162435A1 (de) * 2001-12-19 2003-07-17 Joerg Lahann Verfahren zur Erzeugung von Oberflächenbeschichtungen, die die Adsorption von Proteinen bzw. die Adhäsion von Bakterien und/oder Zellen vermindern
US7217512B2 (en) * 2002-05-09 2007-05-15 Corning Incorporated Reagent and method for attaching target molecules to a surface
DE10233303A1 (de) * 2002-07-22 2004-02-12 Micronas Holding Gmbh Sensoroberfläche mit verbessertem Signal/Rausch-Verhältnis
DE60211685T2 (de) * 2002-08-02 2007-05-10 Sony Deutschland Gmbh Verfahren zur Bindung hydophiler Substanzen an hydrophile Makromoleküle und Immobilisierung derselben auf hydrophoben Oberflächen
US20050233473A1 (en) * 2002-08-16 2005-10-20 Zyomyx, Inc. Methods and reagents for surface functionalization
US20040076961A1 (en) * 2002-10-21 2004-04-22 Lewis Mark A. Biomolecule retaining material and methods for attaching biomolecules to a surface
US7195908B2 (en) * 2002-10-31 2007-03-27 Corning Incorporated Supports treated with triamine for immobilizing biomolecules
EP1581582B2 (de) 2003-01-06 2017-06-07 Nektar Therapeutics Thiolselektive wasserlösliche polymerderivate
US20040151766A1 (en) * 2003-01-30 2004-08-05 Monahan Sean D. Protein and peptide delivery to mammalian cells in vitro
EP1625147B1 (de) * 2003-05-21 2008-01-23 Ares Trading S.A. Verfahren zur chromatographischen analyse einer proteinlösung
US7135821B2 (en) * 2003-10-01 2006-11-14 Altera Corporation High-definition cathode ray tube and electron gun
US20050153320A1 (en) * 2003-11-06 2005-07-14 Herron James N. Single base extension
US8048437B2 (en) * 2004-04-21 2011-11-01 Richard Nagler Medical device with surface coating comprising bioactive compound
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
ATE494012T1 (de) * 2004-12-21 2011-01-15 Nektar Therapeutics Stabilisierte polymer-thiol-reagenzien
US20060147943A1 (en) * 2004-12-30 2006-07-06 Lewis Mark A Substrates having pendant epoxide groups for binding biomolecules and methods of making and using thereof
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
US7743730B2 (en) * 2005-12-21 2010-06-29 Lam Research Corporation Apparatus for an optimized plasma chamber grounded electrode assembly
US20070225795A1 (en) * 2006-03-24 2007-09-27 Juan Granada Composite vascular prosthesis
CN101529251B (zh) 2006-11-01 2014-04-02 贝克曼考尔特公司 用于亲合分析的结合性表面
EP2114667B1 (de) * 2007-01-24 2020-07-29 Ethox Chemicals, Llc Verfahren zur verbesserung der wassertransporteigenschaften wasserabweisender oberflächen
US9107815B2 (en) 2008-02-22 2015-08-18 Allergan, Inc. Sustained release poloxamer containing pharmaceutical compositions
EP2626703B1 (de) * 2008-03-27 2017-05-03 Promega Corporation Proteinetikettierung mit Cyanbenzothiazol-Konjugaten
EP2411477A1 (de) 2009-03-25 2012-02-01 DSM IP Assets B.V. Verbesserter anti-biofouling-lack
EP2442839B1 (de) * 2009-04-09 2017-10-04 The University of Queensland Blockcopolymermischungen
US8623292B2 (en) 2010-08-17 2014-01-07 Kimberly-Clark Worldwide, Inc. Dehydration sensors with ion-responsive and charged polymeric surfactants

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Also Published As

Publication number Publication date
CA2163519A1 (en) 1995-03-02
EP0701697A4 (de) 1996-07-10
US5516703A (en) 1996-05-14
WO1995006251A1 (en) 1995-03-02
DE69429345D1 (de) 2002-01-17
US5728588A (en) 1998-03-17
EP0701697B1 (de) 2001-12-05
CA2163519C (en) 2006-11-21
EP0701697A1 (de) 1996-03-20

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