DE3685046D1 - Beschichtete transplantate und verfahren zu ihrer herstellung. - Google Patents

Beschichtete transplantate und verfahren zu ihrer herstellung.

Info

Publication number
DE3685046D1
DE3685046D1 DE8686301712T DE3685046T DE3685046D1 DE 3685046 D1 DE3685046 D1 DE 3685046D1 DE 8686301712 T DE8686301712 T DE 8686301712T DE 3685046 T DE3685046 T DE 3685046T DE 3685046 D1 DE3685046 D1 DE 3685046D1
Authority
DE
Germany
Prior art keywords
production
transplants
transplant
layer
bonding bridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686301712T
Other languages
English (en)
Inventor
Kent C Cochrum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, University of California Berkeley filed Critical University of California
Application granted granted Critical
Publication of DE3685046D1 publication Critical patent/DE3685046D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Chemically Coating (AREA)
  • Fertilizers (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Electroplating Methods And Accessories (AREA)
  • Catalysts (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE8686301712T 1985-03-14 1986-03-11 Beschichtete transplantate und verfahren zu ihrer herstellung. Expired - Lifetime DE3685046D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71166485A 1985-03-14 1985-03-14

Publications (1)

Publication Number Publication Date
DE3685046D1 true DE3685046D1 (de) 1992-06-04

Family

ID=24859010

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686301712T Expired - Lifetime DE3685046D1 (de) 1985-03-14 1986-03-11 Beschichtete transplantate und verfahren zu ihrer herstellung.

Country Status (10)

Country Link
US (1) US4696286A (de)
EP (1) EP0195577B1 (de)
JP (1) JPH07100661B2 (de)
AT (1) ATE75409T1 (de)
CA (1) CA1267851A (de)
DE (1) DE3685046D1 (de)
DK (1) DK165221C (de)
FI (1) FI90628C (de)
IL (1) IL78110A (de)
NO (1) NO166836C (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935000A (en) * 1986-04-03 1990-06-19 East Carolina University Extracellular matrix induction method to produce pancreatic islet tissue
US5128170A (en) * 1989-05-11 1992-07-07 Kanegafunchi Kagaku Kogyo Kabushiki Kaisha Method for manufacturing medical device having a highly biocompatible surface
JPH05501971A (ja) * 1989-09-15 1993-04-15 カイロン・オフサルミクス・インコーポレイテッド 合成レンズの上皮化達成法
IL103284A0 (en) * 1991-10-31 1993-02-21 Transtech Medical Inc Transplant protective coating
DE69327281T2 (de) * 1992-02-24 2000-08-10 Encelle, Inc. Künstliche endokrine vorrichtung
US6231881B1 (en) * 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US5824331A (en) * 1992-02-24 1998-10-20 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US5834005A (en) * 1992-02-24 1998-11-10 Encelle, Inc. Bioartificial devices and cellular matrices therefor
ATE207727T1 (de) * 1992-05-29 2001-11-15 Univ California Beschichtetes transplantat sowie herstellungsverfahren dafür
US5578314A (en) * 1992-05-29 1996-11-26 The Regents Of The University Of California Multiple layer alginate coatings of biological tissue for transplantation
US5429821A (en) * 1992-05-29 1995-07-04 The Regents Of The University Of California Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use
US5399665A (en) * 1992-11-05 1995-03-21 Massachusetts Institute Of Technology Biodegradable polymers for cell transplantation
WO1994018906A1 (en) * 1993-02-18 1994-09-01 New England Deaconess Hospital, Corp. Implantable artificial organ
AU695120B2 (en) * 1993-06-07 1998-08-06 Baylor College Of Medicine Use of an MHC class I suppressor drug for the treatment of autoimmune diseases and transplantation rejection
US5876742A (en) * 1994-01-24 1999-03-02 The Regents Of The University Of California Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof
US6703017B1 (en) 1994-04-28 2004-03-09 Ixion Biotechnology, Inc. Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
EP0759692B1 (de) * 1994-05-20 2009-02-25 Breonics, Inc. Verfahren zur überwachung der lebensfähigkeit transplantabler organe
WO1995031944A1 (en) * 1994-05-20 1995-11-30 Vec Tec, Inc. Methods rendering grafts nonthrombogenic and substantially nonimmunogenic
US5882328A (en) * 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
US5916790A (en) * 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
JPH11501512A (ja) * 1995-03-03 1999-02-09 メタボレックス，インコーポレイティド ゲル化ポリマーによる新規の被包方法
EP0747046A3 (de) * 1995-05-19 1997-12-03 Baxter International Inc. Durchlässige Immunoisolationsmembranstrukturen für Zellimplantation in einem Wirtsgewebe
US6060640A (en) * 1995-05-19 2000-05-09 Baxter International Inc. Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
EP0877555B1 (de) * 1995-09-27 2007-08-22 Emory University Verwendung eines inhibitors eines kostimulatorischen vorgangs des immunsystems zur herstellung eines medikaments zum schutz transplantierter, nichtembryonaler lebender zellen vor zerstörung durch das immunsystem
US7041634B2 (en) 1995-09-27 2006-05-09 Emory University Method of inhibiting immune system destruction of transplanted viable cells
US5855613A (en) * 1995-10-13 1999-01-05 Islet Sheet Medical, Inc. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change
EP1586284B1 (de) * 1995-10-26 2009-02-18 Paul P. Latta Induktion von immunologischer Toleranz
EP0822857A1 (de) * 1996-02-23 1998-02-11 Circe Biomedical, Inc. Neuartige künstliche bauchspeicheldrüse
US6364907B1 (en) 1998-10-09 2002-04-02 Qlt Inc. Method to prevent xenograft transplant rejection
AU1617800A (en) * 1998-11-12 2000-05-29 Polymer Biosciences, Inc. Hemostatic polymer useful for rapid blood coagulation and hemostasis
CA2376375C (en) * 1999-06-05 2011-07-12 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for inhibiting cardiovascular cell proliferation
EP1224259A4 (de) * 1999-09-27 2005-04-27 Univ Florida Rückbildung von insulinabhängigem diabetes durch inselbildende stammzellen, inselvorläuferzellen und inselähnliche strukturen
US20040208855A1 (en) * 1999-11-17 2004-10-21 Allison Beth Anne Use of PDT to inhibit intimal hyperplasia
WO2001070022A1 (fr) * 2000-03-21 2001-09-27 Yuichi Mori Materiaux de revetement pour tissus biologiques, tissus biologiques revetus et procede d'enduction de tissus biologiques
DE60115433T2 (de) * 2000-05-31 2006-08-03 Encelle, Inc. Verfahren zur behandlung von chronischen geschwüren
AU2001273234A1 (en) * 2000-07-05 2002-01-14 Islet Technology, Inc. Method and system for consistent and effective encapsulation of biological material
KR100380569B1 (ko) * 2000-10-24 2003-04-26 주식회사 메디프렉스 고분자 결합을 이용한 췌장소도 막의 표면개질 방법
WO2002035929A1 (en) * 2000-11-03 2002-05-10 Vitrolife Ab Evaluation and preservation solution
US7101862B2 (en) * 2001-12-31 2006-09-05 Area Laboratories, Llc Hemostatic compositions and methods for controlling bleeding
US20070248653A1 (en) * 2006-04-20 2007-10-25 Cochrum Kent C Hemostatic compositions and methods for controlling bleeding
BRPI0808191A2 (pt) * 2007-02-02 2017-05-23 Converge Biotech Inc dispositivos implantáveis híbridos terapêuticos
US20100021538A1 (en) * 2008-02-29 2010-01-28 Youngro Byun Pharmaceutical compositions containing heparin derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915369D0 (pt) * 1969-02-27 1973-03-13 Bayer Ag Emprego de inibidores biologicos de proteases para conservacao de orgaos tecidos e alimentos
US3629390A (en) * 1969-12-18 1971-12-21 Us Interior Avian specific bio-affecting preparation and treatment method
IL47062A (en) * 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
US4251387A (en) * 1979-04-17 1981-02-17 Damon Corporation Process for preparing semipermeable microcapsules
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
JPS6059010B2 (ja) * 1979-10-02 1985-12-23 工業技術院長 マイクロカプセル
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4407957A (en) * 1981-03-13 1983-10-04 Damon Corporation Reversible microencapsulation of a core material
US4495288A (en) * 1981-03-13 1985-01-22 Damon Biotech, Inc. Method of culturing anchorage dependent cells
US4439521A (en) * 1981-10-21 1984-03-27 Ontario Cancer Institute Method for producing self-reproducing mammalian pancreatic islet-like structures
JPS6018179A (ja) * 1983-07-12 1985-01-30 三浦　喜温 人工肝臓用材料
IL72787A (en) * 1983-09-01 1987-12-31 Damon Biotech Inc Polyionic microencapsulation of viable cells
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
GB8500121D0 (en) * 1985-01-03 1985-02-13 Connaught Lab Microencapsulation of living cells

Also Published As

Publication number Publication date
FI861083A0 (fi) 1986-03-14
DK119286D0 (da) 1986-03-14
NO860858L (no) 1986-09-15
EP0195577A2 (de) 1986-09-24
US4696286A (en) 1987-09-29
FI861083A (fi) 1986-09-15
NO166836B (no) 1991-06-03
FI90628B (fi) 1993-11-30
NO166836C (no) 1991-09-11
DK165221B (da) 1992-10-26
JPH07100661B2 (ja) 1995-11-01
FI90628C (fi) 1994-03-10
DK119286A (da) 1986-09-15
ATE75409T1 (de) 1992-05-15
IL78110A0 (en) 1986-07-31
JPS61222443A (ja) 1986-10-02
IL78110A (en) 1991-04-15
CA1267851A (en) 1990-04-17
DK165221C (da) 1993-03-22
EP0195577B1 (de) 1992-04-29
EP0195577A3 (en) 1988-08-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee