DE3678343D1 - Expressionskontrollsequenzen fuer gram-positive bakterien. - Google Patents

Expressionskontrollsequenzen fuer gram-positive bakterien.

Info

Publication number
DE3678343D1
DE3678343D1 DE8686108774T DE3678343T DE3678343D1 DE 3678343 D1 DE3678343 D1 DE 3678343D1 DE 8686108774 T DE8686108774 T DE 8686108774T DE 3678343 T DE3678343 T DE 3678343T DE 3678343 D1 DE3678343 D1 DE 3678343D1
Authority
DE
Germany
Prior art keywords
gram
expression control
expression
dna sequences
positive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686108774T
Other languages
English (en)
Inventor
Hermann Prof Dr Bujard
Grice Stuart Dr Le
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE3678343D1 publication Critical patent/DE3678343D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8686108774T 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien. Expired - Lifetime DE3678343D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858517071A GB8517071D0 (en) 1985-07-05 1985-07-05 Gram-positive expression control sequence

Publications (1)

Publication Number Publication Date
DE3678343D1 true DE3678343D1 (de) 1991-05-02

Family

ID=10581857

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686108774T Expired - Lifetime DE3678343D1 (de) 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien.

Country Status (12)

Country Link
US (1) US4868111A (de)
EP (1) EP0207459B1 (de)
JP (2) JP2632809B2 (de)
AT (1) ATE62020T1 (de)
AU (1) AU594349B2 (de)
CA (1) CA1316850C (de)
DE (1) DE3678343D1 (de)
DK (1) DK175206B1 (de)
GB (1) GB8517071D0 (de)
IE (1) IE59165B1 (de)
IL (1) IL79291A (de)
NZ (1) NZ216688A (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266474A (en) * 1987-06-24 1993-11-30 Genentech, Inc. Balanced inducible transcription system
EP0303925B1 (de) * 1987-08-17 1995-06-07 F. Hoffmann-La Roche Ag Hochreprimierbare Expressionskontrollsequenzen
US5726042A (en) * 1988-04-07 1998-03-10 Abbott Laboratories Expression of heterologous proteins in Bacillus megaterium utilizing sporulation promoters of Bacillus subtilis
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
FR2679568B1 (fr) * 1991-07-22 1994-09-02 Pasteur Institut Nouveau type de replicon gram-positif - construction de vecteurs recombinants le contenant.
JPH07504815A (ja) 1992-02-27 1995-06-01 マイクロバイアル　テクニクス　リミティド 乳酸菌における異種遺伝子の発現およびその発現産物
US6022730A (en) * 1994-06-17 2000-02-08 Robinson; Douglas H. Methods for the isolation of bacteria containing eukaryotic genes
US5629205A (en) * 1995-05-19 1997-05-13 Allelix Biopharmaceuticals Inc. Promoters for gene expression
US6194168B1 (en) * 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
US6146848A (en) * 1998-07-23 2000-11-14 The Hong Kong University Of Science & Technology Bacterial expression system
US6720174B1 (en) 1999-01-28 2004-04-13 Novozymes A/S Phytases
EP2502998A3 (de) * 1999-04-09 2013-02-27 Intercell USA, Inc. Rekombinanter Toxin A-/Toxin B-Impfstoff gegen Clostridium difficile
DE60142609D1 (de) * 2000-10-25 2010-09-02 Fujifilm Corp Methode zur Analyse doppelsträngiger DNA
WO2003065973A2 (en) * 2001-10-26 2003-08-14 Id Biomedical Corporation Of Washington Multivalent streptococcal vaccine compositions and methods for use
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
JP5087741B2 (ja) 2003-11-19 2012-12-05 フェネックス インコーポレイテッド 改良タンパク質発現系
CA2546157C (en) 2003-11-21 2014-07-22 Dow Global Technolgies Inc. Improved expression systems with sec-system secretion
KR101183720B1 (ko) 2004-01-16 2012-09-17 다우 글로벌 테크놀로지스 엘엘씨 슈도모나스 플루오레센스에서의 포유류 단백질의 발현
JP2008507294A (ja) 2004-07-26 2008-03-13 ダウ グローバル テクノロジーズ インコーポレイティド 菌株遺伝子操作による改善されたタンパク質発現のための方法
GB0602173D0 (en) * 2006-02-03 2006-03-15 Avecia Ltd Expression system
CN105664141A (zh) 2006-10-18 2016-06-15 派利尼斯有限公司 脱氧核糖核酸酶在制备用于治疗男性低生育力的药物中的应用
EP2468869B1 (de) 2007-01-31 2015-03-18 Pfenex Inc. Bakterielle Leader-Sequenzen für erhöhte Expression
AU2008245696B2 (en) 2007-04-27 2013-11-07 Pelican Technology Holdings, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9243253B2 (en) 2009-05-11 2016-01-26 Pfenex, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
NZ602255A (en) 2010-03-04 2014-04-30 Pfenex Inc Method for producing soluble recombinant interferon protein without denaturing
NZ602958A (en) 2010-03-30 2014-07-25 Pfenex Inc High level expression of recombinant toxin proteins
PL2552949T3 (pl) 2010-04-01 2017-01-31 Pfenex Inc. Sposoby wytwarzania G-CSF w komórce gospodarza Pseudomonas
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US11408007B2 (en) 2014-09-26 2022-08-09 Yale University Compositions and methods for biocontainment of microorganisms
KR102353262B1 (ko) 2014-12-01 2022-01-18 피페넥스 인크. 펩티드 생산용 융합 파트너
EP3700921A4 (de) 2017-10-27 2021-12-15 Pfenex Inc. Verfahren zur herstellung von rekombinanter erwinia asparaginase
KR20200073280A (ko) 2017-10-27 2020-06-23 피페넥스 인크. 주변세포질 단백질 발현을 위한 박테리아 리더 서열
US11149280B2 (en) 2019-10-29 2021-10-19 Yale University Engineering organisms resistant to viruses and horizontally transferred genetic elements
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase
WO2023178316A2 (en) 2022-03-17 2023-09-21 Yale University Compositions and methods for expressing synthetic genetic elements across diverse microorganisms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495280A (en) * 1981-05-20 1985-01-22 The Board Of Trustees Of The Leland Stanford Jr. University Cloned high signal strength promoters
GR81701B (de) 1983-01-18 1984-12-12 Lilly Co Eli
EP0115936A1 (de) * 1983-01-24 1984-08-15 Kabushiki Kaisha Yakult Honsha Chimere Plasmide

Also Published As

Publication number Publication date
IE59165B1 (en) 1994-01-12
JPH10229878A (ja) 1998-09-02
IL79291A0 (en) 1986-09-30
EP0207459A2 (de) 1987-01-07
AU594349B2 (en) 1990-03-08
CA1316850C (en) 1993-04-27
IL79291A (en) 1991-06-30
IE861806L (en) 1987-01-05
DK320686D0 (da) 1986-07-04
ATE62020T1 (de) 1991-04-15
EP0207459A3 (en) 1988-07-06
US4868111A (en) 1989-09-19
GB8517071D0 (en) 1985-08-14
AU5938586A (en) 1987-01-08
JP2632809B2 (ja) 1997-07-23
JPS6214786A (ja) 1987-01-23
DK320686A (da) 1987-01-06
DK175206B1 (da) 2004-07-12
JP2887248B2 (ja) 1999-04-26
EP0207459B1 (de) 1991-03-27
NZ216688A (en) 1990-06-26

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