ATE62020T1 - Expressionskontrollsequenzen fuer gram-positive bakterien. - Google Patents

Expressionskontrollsequenzen fuer gram-positive bakterien.

Info

Publication number
ATE62020T1
ATE62020T1 AT86108774T AT86108774T ATE62020T1 AT E62020 T1 ATE62020 T1 AT E62020T1 AT 86108774 T AT86108774 T AT 86108774T AT 86108774 T AT86108774 T AT 86108774T AT E62020 T1 ATE62020 T1 AT E62020T1
Authority
AT
Austria
Prior art keywords
gram
expression control
expression
dna sequences
positive
Prior art date
Application number
AT86108774T
Other languages
English (en)
Inventor
Hermann Prof Dr Bujard
Grice Stuart Dr Le
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE62020T1 publication Critical patent/ATE62020T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/832Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT86108774T 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien. ATE62020T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517071A GB8517071D0 (en) 1985-07-05 1985-07-05 Gram-positive expression control sequence
EP86108774A EP0207459B1 (de) 1985-07-05 1986-06-27 Expressionskontrollsequenzen für gram-positive Bakterien

Publications (1)

Publication Number Publication Date
ATE62020T1 true ATE62020T1 (de) 1991-04-15

Family

ID=10581857

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86108774T ATE62020T1 (de) 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien.

Country Status (12)

Country Link
US (1) US4868111A (de)
EP (1) EP0207459B1 (de)
JP (2) JP2632809B2 (de)
AT (1) ATE62020T1 (de)
AU (1) AU594349B2 (de)
CA (1) CA1316850C (de)
DE (1) DE3678343D1 (de)
DK (1) DK175206B1 (de)
GB (1) GB8517071D0 (de)
IE (1) IE59165B1 (de)
IL (1) IL79291A (de)
NZ (1) NZ216688A (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266474A (en) * 1987-06-24 1993-11-30 Genentech, Inc. Balanced inducible transcription system
EP0303925B1 (de) * 1987-08-17 1995-06-07 F. Hoffmann-La Roche Ag Hochreprimierbare Expressionskontrollsequenzen
US5726042A (en) * 1988-04-07 1998-03-10 Abbott Laboratories Expression of heterologous proteins in Bacillus megaterium utilizing sporulation promoters of Bacillus subtilis
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
FR2679568B1 (fr) * 1991-07-22 1994-09-02 Pasteur Institut Nouveau type de replicon gram-positif - construction de vecteurs recombinants le contenant.
JPH07504815A (ja) 1992-02-27 1995-06-01 マイクロバイアル テクニクス リミティド 乳酸菌における異種遺伝子の発現およびその発現産物
US6022730A (en) * 1994-06-17 2000-02-08 Robinson; Douglas H. Methods for the isolation of bacteria containing eukaryotic genes
US5629205A (en) * 1995-05-19 1997-05-13 Allelix Biopharmaceuticals Inc. Promoters for gene expression
US6194168B1 (en) * 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
US6146848A (en) * 1998-07-23 2000-11-14 The Hong Kong University Of Science & Technology Bacterial expression system
US6720174B1 (en) 1999-01-28 2004-04-13 Novozymes A/S Phytases
WO2000061762A1 (en) * 1999-04-09 2000-10-19 Techlab, Inc. RECOMBINANT TOXIN A/TOXIN B VACCINE AGAINST $i(CLOSTRIDIUM DIFFICILE)
EP1201767B1 (de) * 2000-10-25 2010-07-21 FUJIFILM Corporation Methode zur Analyse doppelsträngiger DNA
AU2002365184A1 (en) * 2001-10-26 2003-07-30 Id Biomedical Corporation Of Washington Efficient protein expression system
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
BRPI0416744A (pt) 2003-11-19 2007-01-16 Dow Global Technologies Inc sistemas de expressão de proteìna aperfeiçoados
AU2004317306B2 (en) 2003-11-21 2010-09-02 Pelican Technology Holdings, Inc. Improved expression systems with Sec-system secretion
ES2707786T3 (es) 2004-01-16 2019-04-05 Pfenex Inc Expresión de proteínas de mamífero en Pseudomonas fluorescens
EP2412816B1 (de) 2004-07-26 2014-12-03 Pfenex Inc. Verfahren zur verbesserten Proteinexpression durch Strain-Engineering
GB0602173D0 (en) * 2006-02-03 2006-03-15 Avecia Ltd Expression system
EP2086642B1 (de) * 2006-10-18 2014-06-25 Periness Ltd. Dnase zur behandlung von subfertilität beim mann
US7618799B2 (en) 2007-01-31 2009-11-17 Dow Global Technologies Inc Bacterial leader sequences for increased expression
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
MX2009011523A (es) 2007-04-27 2009-11-09 Dow Global Technologies Inc Metodo para clasificar rapidamente huespedes microbianos para identificar ciertas cepas con rendimiento y/o calidad mejorados en la expresion de proteinas heterologas.
US9243253B2 (en) 2009-05-11 2016-01-26 Pfenex, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
CN102906108B (zh) 2010-03-04 2016-01-20 菲尼克斯公司 用于无变性制备可溶性重组干扰素蛋白的方法
EP2553102B1 (de) 2010-03-30 2015-12-09 Pfenex Inc. Hochleistungs-expression rekombinanter toxinproteine
PL2552949T3 (pl) 2010-04-01 2017-01-31 Pfenex Inc. Sposoby wytwarzania G-CSF w komórce gospodarza Pseudomonas
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US11408007B2 (en) 2014-09-26 2022-08-09 Yale University Compositions and methods for biocontainment of microorganisms
AU2015355242B2 (en) 2014-12-01 2020-10-08 Pelican Technology Holdings, Inc. Fusion partners for peptide production
SG11202002943PA (en) 2017-10-27 2020-05-28 Pfenex Inc Method for production of recombinant erwinia asparaginase
WO2019083795A1 (en) 2017-10-27 2019-05-02 Pfenex Inc. GUIDED BACTERIAL SEQUENCES FOR EXPRESSION OF PERIPLASMIC PROTEINS
US11149280B2 (en) 2019-10-29 2021-10-19 Yale University Engineering organisms resistant to viruses and horizontally transferred genetic elements
US20220313798A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase
WO2023178316A2 (en) 2022-03-17 2023-09-21 Yale University Compositions and methods for expressing synthetic genetic elements across diverse microorganisms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495280A (en) * 1981-05-20 1985-01-22 The Board Of Trustees Of The Leland Stanford Jr. University Cloned high signal strength promoters
GR81701B (de) 1983-01-18 1984-12-12 Lilly Co Eli
EP0115936A1 (de) * 1983-01-24 1984-08-15 Kabushiki Kaisha Yakult Honsha Chimere Plasmide

Also Published As

Publication number Publication date
DK320686D0 (da) 1986-07-04
NZ216688A (en) 1990-06-26
JPS6214786A (ja) 1987-01-23
DE3678343D1 (de) 1991-05-02
AU5938586A (en) 1987-01-08
JPH10229878A (ja) 1998-09-02
EP0207459A3 (en) 1988-07-06
GB8517071D0 (en) 1985-08-14
IL79291A0 (en) 1986-09-30
EP0207459B1 (de) 1991-03-27
EP0207459A2 (de) 1987-01-07
DK175206B1 (da) 2004-07-12
IE59165B1 (en) 1994-01-12
AU594349B2 (en) 1990-03-08
US4868111A (en) 1989-09-19
IL79291A (en) 1991-06-30
JP2632809B2 (ja) 1997-07-23
CA1316850C (en) 1993-04-27
DK320686A (da) 1987-01-06
IE861806L (en) 1987-01-05
JP2887248B2 (ja) 1999-04-26

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Legal Events

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time