ATE62020T1 - Expressionskontrollsequenzen fuer gram-positive bakterien. - Google Patents

Expressionskontrollsequenzen fuer gram-positive bakterien.

Info

Publication number
ATE62020T1
ATE62020T1 AT86108774T AT86108774T ATE62020T1 AT E62020 T1 ATE62020 T1 AT E62020T1 AT 86108774 T AT86108774 T AT 86108774T AT 86108774 T AT86108774 T AT 86108774T AT E62020 T1 ATE62020 T1 AT E62020T1
Authority
AT
Austria
Prior art keywords
gram
expression control
expression
dna sequences
positive
Prior art date
Application number
AT86108774T
Other languages
English (en)
Inventor
Hermann Prof Dr Bujard
Grice Stuart Dr Le
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE62020T1 publication Critical patent/ATE62020T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT86108774T 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien. ATE62020T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517071A GB8517071D0 (en) 1985-07-05 1985-07-05 Gram-positive expression control sequence
EP86108774A EP0207459B1 (de) 1985-07-05 1986-06-27 Expressionskontrollsequenzen für gram-positive Bakterien

Publications (1)

Publication Number Publication Date
ATE62020T1 true ATE62020T1 (de) 1991-04-15

Family

ID=10581857

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86108774T ATE62020T1 (de) 1985-07-05 1986-06-27 Expressionskontrollsequenzen fuer gram-positive bakterien.

Country Status (12)

Country Link
US (1) US4868111A (de)
EP (1) EP0207459B1 (de)
JP (2) JP2632809B2 (de)
AT (1) ATE62020T1 (de)
AU (1) AU594349B2 (de)
CA (1) CA1316850C (de)
DE (1) DE3678343D1 (de)
DK (1) DK175206B1 (de)
GB (1) GB8517071D0 (de)
IE (1) IE59165B1 (de)
IL (1) IL79291A (de)
NZ (1) NZ216688A (de)

Families Citing this family (40)

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US5266474A (en) * 1987-06-24 1993-11-30 Genentech, Inc. Balanced inducible transcription system
EP0303925B1 (de) * 1987-08-17 1995-06-07 F. Hoffmann-La Roche Ag Hochreprimierbare Expressionskontrollsequenzen
US5726042A (en) * 1988-04-07 1998-03-10 Abbott Laboratories Expression of heterologous proteins in Bacillus megaterium utilizing sporulation promoters of Bacillus subtilis
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
FR2679568B1 (fr) * 1991-07-22 1994-09-02 Pasteur Institut Nouveau type de replicon gram-positif - construction de vecteurs recombinants le contenant.
EP0628083A1 (de) 1992-02-27 1994-12-14 Microbial Technics Limited Heterologe genexpression in lactococcus und die entsprechenden expressionsprodukte
US6022730A (en) * 1994-06-17 2000-02-08 Robinson; Douglas H. Methods for the isolation of bacteria containing eukaryotic genes
US5629205A (en) * 1995-05-19 1997-05-13 Allelix Biopharmaceuticals Inc. Promoters for gene expression
US6194168B1 (en) * 1997-09-30 2001-02-27 Human Genome Sciences, Inc. Expression control sequences
US6146848A (en) * 1998-07-23 2000-11-14 The Hong Kong University Of Science & Technology Bacterial expression system
US6720174B1 (en) 1999-01-28 2004-04-13 Novozymes A/S Phytases
EP1169456B1 (de) * 1999-04-09 2012-07-11 Intercell USA, Inc. Rekombinante Herstellung vom Toxin A oder Toxin B der Clostridium difficile
ATE474932T1 (de) * 2000-10-25 2010-08-15 Fujifilm Corp Methode zur analyse doppelsträngiger dna
AU2002365184A1 (en) * 2001-10-26 2003-07-30 Id Biomedical Corporation Of Washington Efficient protein expression system
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1692282B1 (de) 2003-11-19 2012-08-08 Pfenex, Inc. Verbesserte Proteinexpressionssysteme in auxotrophem Pseudomonas fluorescens
BRPI0416807A (pt) 2003-11-21 2007-01-09 Dow Global Technologies Inc sistemas de expressão aperfeiçoados com secreção de sistema sec
KR101183720B1 (ko) 2004-01-16 2012-09-17 다우 글로벌 테크놀로지스 엘엘씨 슈도모나스 플루오레센스에서의 포유류 단백질의 발현
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
GB0602173D0 (en) * 2006-02-03 2006-03-15 Avecia Ltd Expression system
DK2086642T3 (da) 2006-10-18 2014-09-29 Periness Ltd Dnase til behandling af subfertilitet hos mænd
KR101491867B1 (ko) 2007-01-31 2015-02-10 피페넥스 인크. 증가된 발현을 위한 박테리아 리더 서열
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
AU2010247938B2 (en) 2009-05-11 2016-02-18 Pelican Technology Holdings, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
MX2012010148A (es) 2010-03-04 2013-01-22 Pfenex Inc Metodo para producir proteinas de interferon recombinantes solubles sin desnaturalizacion.
WO2011126811A2 (en) 2010-03-30 2011-10-13 Pfenex Inc. High level expression of recombinant toxin proteins
PL2552949T3 (pl) 2010-04-01 2017-01-31 Pfenex Inc. Sposoby wytwarzania G-CSF w komórce gospodarza Pseudomonas
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
WO2016073079A2 (en) 2014-09-26 2016-05-12 Yale University Compositions and methods for biocontainment of microorganisms
WO2016089782A1 (en) 2014-12-01 2016-06-09 Pfenex Inc. Fusion partners for peptide production
SG11202002943PA (en) 2017-10-27 2020-05-28 Pfenex Inc Method for production of recombinant erwinia asparaginase
KR102835683B1 (ko) 2017-10-27 2025-07-17 펠리칸 테크놀로지 홀딩스, 인크. 주변세포질 단백질 발현을 위한 박테리아 리더 서열
EP3701036A4 (de) 2017-10-27 2021-09-01 Pfenex Inc. Verfahren zur herstellung von rekombinantem e. coli
WO2021086487A1 (en) 2019-10-29 2021-05-06 Yale University Engineering organisms resistant to viruses and horizontally transferred genetic elements
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase
KR20240021234A (ko) 2021-06-10 2024-02-16 펠리칸 테크놀로지 홀딩스, 인크. 재조합 단백질 발현을 위한 박테리아 숙주
WO2023178316A2 (en) 2022-03-17 2023-09-21 Yale University Compositions and methods for expressing synthetic genetic elements across diverse microorganisms
CN117384923A (zh) * 2023-09-13 2024-01-12 深圳先进技术研究院 表达盒、表达载体、重组微生物、非核糖体肽合成基因簇的异源表达方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495280A (en) * 1981-05-20 1985-01-22 The Board Of Trustees Of The Leland Stanford Jr. University Cloned high signal strength promoters
GR81701B (de) 1983-01-18 1984-12-12 Lilly Co Eli
EP0115936A1 (de) * 1983-01-24 1984-08-15 Kabushiki Kaisha Yakult Honsha Chimere Plasmide

Also Published As

Publication number Publication date
IE59165B1 (en) 1994-01-12
IL79291A0 (en) 1986-09-30
EP0207459A2 (de) 1987-01-07
CA1316850C (en) 1993-04-27
IL79291A (en) 1991-06-30
IE861806L (en) 1987-01-05
JP2887248B2 (ja) 1999-04-26
AU5938586A (en) 1987-01-08
GB8517071D0 (en) 1985-08-14
US4868111A (en) 1989-09-19
EP0207459B1 (de) 1991-03-27
JPH10229878A (ja) 1998-09-02
DK175206B1 (da) 2004-07-12
DK320686D0 (da) 1986-07-04
JPS6214786A (ja) 1987-01-23
AU594349B2 (en) 1990-03-08
JP2632809B2 (ja) 1997-07-23
DK320686A (da) 1987-01-06
NZ216688A (en) 1990-06-26
DE3678343D1 (de) 1991-05-02
EP0207459A3 (en) 1988-07-06

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Legal Events

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time