DE3600487A1 - Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung - Google Patents

Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung

Info

Publication number
DE3600487A1
DE3600487A1 DE19863600487 DE3600487A DE3600487A1 DE 3600487 A1 DE3600487 A1 DE 3600487A1 DE 19863600487 DE19863600487 DE 19863600487 DE 3600487 A DE3600487 A DE 3600487A DE 3600487 A1 DE3600487 A1 DE 3600487A1
Authority
DE
Germany
Prior art keywords
culture medium
culture
gas
chamber
space
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19863600487
Other languages
German (de)
English (en)
Inventor
Rolf Dr Gebhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19863600487 priority Critical patent/DE3600487A1/de
Priority to JP61308094A priority patent/JPS62171674A/ja
Priority to DE8787100068T priority patent/DE3781811D1/de
Priority to EP87100068A priority patent/EP0230223B1/de
Priority to AT87100068T priority patent/ATE80910T1/de
Publication of DE3600487A1 publication Critical patent/DE3600487A1/de
Priority to US07/441,338 priority patent/US5010014A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19863600487 1986-01-10 1986-01-10 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung Withdrawn DE3600487A1 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE19863600487 DE3600487A1 (de) 1986-01-10 1986-01-10 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung
JP61308094A JPS62171674A (ja) 1986-01-10 1986-12-25 培養用周囲融合装置と周囲融合培養方法
DE8787100068T DE3781811D1 (de) 1986-01-10 1987-01-06 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung.
EP87100068A EP0230223B1 (de) 1986-01-10 1987-01-06 Perifusionsgerät für die Züchtung lebender Zellen und Verfahren zur Perifusions-Kultivierung
AT87100068T ATE80910T1 (de) 1986-01-10 1987-01-06 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung.
US07/441,338 US5010014A (en) 1986-01-10 1989-11-21 Perifusion apparatus for culturing living cells and perifusion culturing process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863600487 DE3600487A1 (de) 1986-01-10 1986-01-10 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung

Publications (1)

Publication Number Publication Date
DE3600487A1 true DE3600487A1 (de) 1987-07-16

Family

ID=6291607

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19863600487 Withdrawn DE3600487A1 (de) 1986-01-10 1986-01-10 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung
DE8787100068T Expired - Lifetime DE3781811D1 (de) 1986-01-10 1987-01-06 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8787100068T Expired - Lifetime DE3781811D1 (de) 1986-01-10 1987-01-06 Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung.

Country Status (5)

Country Link
US (1) US5010014A (ja)
EP (1) EP0230223B1 (ja)
JP (1) JPS62171674A (ja)
AT (1) ATE80910T1 (ja)
DE (2) DE3600487A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011106914A1 (de) * 2011-07-08 2013-01-10 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839292B1 (en) * 1987-09-11 1994-09-13 Joseph G Cremonese Cell culture flask utilizing membrane barrier
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
DE4116727C2 (de) 1991-05-17 1995-09-07 Uwe Dr Marx Verfahren und Vorrichtung zur gleichzeitigen Kultivierung unterschiedlicher Säugerzellen
US5437998A (en) * 1993-09-09 1995-08-01 Synthecon, Inc. Gas permeable bioreactor and method of use
FR2762092B1 (fr) 1997-04-15 1999-05-28 Bio Merieux Procede et dispositif de remplissage avec un milieu liquide d'une carte d'analyse
US6001642A (en) * 1998-06-29 1999-12-14 Wyle Laboratories, Inc. Life Sciences Bioreactor and cell culturing processes using the bioreactor
EP1599571B1 (en) * 2003-02-28 2013-04-10 Nunc A/S A tray stack adapted for active gassing
US7867761B2 (en) * 2003-02-28 2011-01-11 Nunc A/S Tray stack adapted for active gassing
JP2007537759A (ja) * 2004-05-19 2007-12-27 マサチューセッツ・インスティテュート・オブ・テクノロジー 灌流三次元細胞／組織疾患モデル
JP2008539738A (ja) * 2005-05-09 2008-11-20 サクソニア バイオテック ゲーエムベーハー 細胞培養モジュール用供給システム
EP2089506A2 (en) * 2006-11-07 2009-08-19 Saxonia Bio Tec GmbH Supply system for cell culture module
GB0906836D0 (en) * 2009-04-21 2009-06-03 Cymtox Ltd Consumable component kit
WO2011103359A2 (en) * 2010-02-17 2011-08-25 Inq Biosciences Corporation Culture systems, apparatus, and related methods and articles
DE102016119391B3 (de) * 2016-10-12 2018-01-18 Yoen Ok Roth Mikrobioreaktor-Modul
WO2019113109A1 (en) * 2017-12-04 2019-06-13 Entox Sciences, Inc. Pressure-driven, adjustable throughput fluidics for tissue and cell perifusions
EP3502231B1 (de) * 2017-12-19 2020-08-05 Eppendorf AG Bioprozess-steuervorrichtung sowie bioprozess-system
CN110408542A (zh) * 2019-08-22 2019-11-05 合肥学院 一种气液相培养的皮肤芯片
WO2024112917A1 (en) * 2022-11-22 2024-05-30 The University Of North Carolina At Chapel Hill Laminar flow incorporated scaffold-based 3d cell cultures

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416993A (en) * 1981-06-11 1983-11-22 Mcleod & Miller (Engineers) Limited Apparatus with semi-permeable membrane, and method for cultivating micro-organisms
DE3409501A1 (de) * 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732149A (en) * 1970-09-16 1973-05-08 Farmitalla Soc Apparatus for the large scale growth of living cells
US3843454A (en) * 1972-07-31 1974-10-22 Abbott Lab Flow through tissue culture propagator
DE2624047C3 (de) * 1976-05-28 1980-07-03 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Massenzüchtung von Zellen und Kammer-System zu ihrer Durchführung
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
US4228243A (en) * 1978-07-13 1980-10-14 Toray Industries, Inc. Cell culture propagation apparatus
US4748124A (en) * 1984-10-30 1988-05-31 E. I. Du Pont De Nemours And Company Compartmentalized cell-culture device and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416993A (en) * 1981-06-11 1983-11-22 Mcleod & Miller (Engineers) Limited Apparatus with semi-permeable membrane, and method for cultivating micro-organisms
DE3409501A1 (de) * 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011106914A1 (de) * 2011-07-08 2013-01-10 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen
DE102011106914B4 (de) * 2011-07-08 2015-08-27 Zellwerk Gmbh Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen

Also Published As

Publication number Publication date
EP0230223B1 (de) 1992-09-23
ATE80910T1 (de) 1992-10-15
DE3781811D1 (de) 1992-10-29
EP0230223A3 (en) 1988-11-30
JPS62171674A (ja) 1987-07-28
EP0230223A2 (de) 1987-07-29
US5010014A (en) 1991-04-23

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Legal Events

Date Code Title Description
OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C12M 3/06

8130 Withdrawal