DE3590080T - 1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung - Google Patents

1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung

Info

Publication number
DE3590080T
DE3590080T DE19853590080 DE3590080T DE3590080T DE 3590080 T DE3590080 T DE 3590080T DE 19853590080 DE19853590080 DE 19853590080 DE 3590080 T DE3590080 T DE 3590080T DE 3590080 T DE3590080 T DE 3590080T
Authority
DE
Germany
Prior art keywords
compound
compounds
vitamin
mixture
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19853590080
Other languages
German (de)
English (en)
Other versions
DE3590080C2 (da
Inventor
Hector F. Deluca
Heinrich K. Madison Wis. Schnoes
Rafal R. Warschau/Warszawa Sicinski
Yoko Delmar N.Y. Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE3590080T publication Critical patent/DE3590080T/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19853590080 1984-03-05 1985-01-22 1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung Pending DE3590080T (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58616084A 1984-03-05 1984-03-05

Publications (1)

Publication Number Publication Date
DE3590080T true DE3590080T (de) 1986-02-20

Family

ID=24344548

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3590080A Expired - Lifetime DE3590080C2 (da) 1984-03-05 1985-01-22
DE19853590080 Pending DE3590080T (de) 1984-03-05 1985-01-22 1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3590080A Expired - Lifetime DE3590080C2 (da) 1984-03-05 1985-01-22

Country Status (12)

Country Link
JP (1) JPH064536B2 (da)
AU (1) AU584071B2 (da)
BE (1) BE901879A (da)
CH (1) CH667658A5 (da)
DE (2) DE3590080C2 (da)
DK (1) DK153145C (da)
FR (1) FR2560597B1 (da)
GB (1) GB2155478B (da)
IE (1) IE57951B1 (da)
IL (1) IL74168A (da)
NL (1) NL8520021A (da)
WO (1) WO1985003939A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
IN171449B (da) * 1990-02-14 1992-10-17 Wisconsin Alumni Res Found
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
US4206131A (en) * 1978-06-19 1980-06-03 The Upjohn Company Compounds and process
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3590021C2 (de) * 1984-01-30 1992-09-10 Wisconsin Alumni Res Found 1alpha-Hydroxyvitamin D-Derivat und dieses enthaltendes Arzneimittel

Also Published As

Publication number Publication date
FR2560597B1 (fr) 1987-12-04
IL74168A (en) 1988-11-15
JPS61501447A (ja) 1986-07-17
DK506985A (da) 1985-11-06
NL8520021A (nl) 1986-02-03
IE850520L (en) 1985-09-05
BE901879A (fr) 1985-07-01
JPH064536B2 (ja) 1994-01-19
GB2155478A (en) 1985-09-25
DK153145B (da) 1988-06-20
FR2560597A1 (fr) 1985-09-06
DK153145C (da) 1988-10-31
IE57951B1 (en) 1993-05-19
DE3590080C2 (da) 1992-08-06
WO1985003939A1 (en) 1985-09-12
GB2155478B (en) 1987-12-16
CH667658A5 (de) 1988-10-31
AU584071B2 (en) 1989-05-18
GB8505486D0 (en) 1985-04-03
IL74168A0 (en) 1985-04-30
AU3889585A (en) 1985-09-24
DK506985D0 (da) 1985-11-04

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