DE3587786T2 - Messung des herzschlagintervalls eines stimulierten herzes, sich anpassender herzschrittmacher und betriebsart. - Google Patents
Messung des herzschlagintervalls eines stimulierten herzes, sich anpassender herzschrittmacher und betriebsart.Info
- Publication number
- DE3587786T2 DE3587786T2 DE3587786T DE3587786T DE3587786T2 DE 3587786 T2 DE3587786 T2 DE 3587786T2 DE 3587786 T DE3587786 T DE 3587786T DE 3587786 T DE3587786 T DE 3587786T DE 3587786 T2 DE3587786 T2 DE 3587786T2
- Authority
- DE
- Germany
- Prior art keywords
- wave
- interval
- heart
- pacemaker
- pulse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000638 stimulation Effects 0.000 claims description 88
- 230000001746 atrial effect Effects 0.000 claims description 72
- 230000004044 response Effects 0.000 claims description 45
- 230000006870 function Effects 0.000 claims description 44
- 230000002861 ventricular Effects 0.000 claims description 38
- 230000000747 cardiac effect Effects 0.000 claims description 36
- 230000008859 change Effects 0.000 claims description 28
- 230000028161 membrane depolarization Effects 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 18
- 238000012545 processing Methods 0.000 claims description 12
- 230000034225 regulation of ventricular cardiomyocyte membrane depolarization Effects 0.000 claims description 9
- 230000008569 process Effects 0.000 claims description 8
- 230000004213 regulation of atrial cardiomyocyte membrane depolarization Effects 0.000 claims description 8
- 238000009499 grossing Methods 0.000 claims description 4
- 230000006461 physiological response Effects 0.000 claims 2
- 238000005259 measurement Methods 0.000 description 69
- 210000002837 heart atrium Anatomy 0.000 description 42
- 238000010586 diagram Methods 0.000 description 40
- 230000036279 refractory period Effects 0.000 description 25
- 238000001514 detection method Methods 0.000 description 20
- 239000008186 active pharmaceutical agent Substances 0.000 description 19
- 239000008280 blood Substances 0.000 description 19
- 210000004369 blood Anatomy 0.000 description 19
- 230000000694 effects Effects 0.000 description 13
- 230000009977 dual effect Effects 0.000 description 12
- 210000005245 right atrium Anatomy 0.000 description 11
- 239000004020 conductor Substances 0.000 description 10
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical compound C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 description 10
- 210000005241 right ventricle Anatomy 0.000 description 8
- 230000008602 contraction Effects 0.000 description 7
- 230000000903 blocking effect Effects 0.000 description 6
- 230000003247 decreasing effect Effects 0.000 description 6
- 230000002269 spontaneous effect Effects 0.000 description 6
- 210000001992 atrioventricular node Anatomy 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 238000000718 qrs complex Methods 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 210000005246 left atrium Anatomy 0.000 description 4
- 210000005240 left ventricle Anatomy 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 210000004165 myocardium Anatomy 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 230000033764 rhythmic process Effects 0.000 description 4
- 210000001013 sinoatrial node Anatomy 0.000 description 4
- 230000001960 triggered effect Effects 0.000 description 4
- 230000005856 abnormality Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 230000002336 repolarization Effects 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 101150021453 ARI1 gene Proteins 0.000 description 2
- 101150107506 ARIH2 gene Proteins 0.000 description 2
- 206010003671 Atrioventricular Block Diseases 0.000 description 2
- 102100038513 E3 ubiquitin-protein ligase ARIH2 Human genes 0.000 description 2
- 210000000709 aorta Anatomy 0.000 description 2
- 101150076105 ari-2 gene Proteins 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010304 firing Methods 0.000 description 2
- 238000012886 linear function Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000002107 myocardial effect Effects 0.000 description 2
- 101150009632 prx2 gene Proteins 0.000 description 2
- 210000001147 pulmonary artery Anatomy 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 230000030074 regulation of atrial cardiomyocyte membrane repolarization Effects 0.000 description 2
- VLCQZHSMCYCDJL-UHFFFAOYSA-N tribenuron methyl Chemical compound COC(=O)C1=CC=CC=C1S(=O)(=O)NC(=O)N(C)C1=NC(C)=NC(OC)=N1 VLCQZHSMCYCDJL-UHFFFAOYSA-N 0.000 description 2
- SPBWHPXCWJLQRU-FITJORAGSA-N 4-amino-8-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide Chemical compound C12=NC=NC(N)=C2C(=O)C(C(=O)N)=CN1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O SPBWHPXCWJLQRU-FITJORAGSA-N 0.000 description 1
- 101100323945 Arabidopsis thaliana ARI3 gene Proteins 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 102100021677 Baculoviral IAP repeat-containing protein 2 Human genes 0.000 description 1
- 102100021662 Baculoviral IAP repeat-containing protein 3 Human genes 0.000 description 1
- 208000010271 Heart Block Diseases 0.000 description 1
- 101000896157 Homo sapiens Baculoviral IAP repeat-containing protein 2 Proteins 0.000 description 1
- 101000896224 Homo sapiens Baculoviral IAP repeat-containing protein 3 Proteins 0.000 description 1
- 231100000136 action limit Toxicity 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 210000001765 aortic valve Anatomy 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000002999 depolarising effect Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000001308 heart ventricle Anatomy 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000004115 mitral valve Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 150000002926 oxygen Chemical class 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 210000003102 pulmonary valve Anatomy 0.000 description 1
- 210000003492 pulmonary vein Anatomy 0.000 description 1
- 239000013643 reference control Substances 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 210000000591 tricuspid valve Anatomy 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 210000002620 vena cava superior Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/716,831 US4712555A (en) | 1984-10-19 | 1985-03-27 | Physiologically responsive pacemaker and method of adjusting the pacing interval thereof |
| PCT/US1985/002010 WO1986005698A1 (en) | 1985-03-27 | 1985-10-11 | Stimulated heart interval measurement, adaptive pacer and method of operation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3587786D1 DE3587786D1 (de) | 1994-05-05 |
| DE3587786T2 true DE3587786T2 (de) | 1995-06-01 |
Family
ID=24879623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3587786T Expired - Lifetime DE3587786T2 (de) | 1985-03-27 | 1985-10-11 | Messung des herzschlagintervalls eines stimulierten herzes, sich anpassender herzschrittmacher und betriebsart. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0220194B1 (enExample) |
| JP (1) | JPS63500845A (enExample) |
| CA (1) | CA1272763A (enExample) |
| DE (1) | DE3587786T2 (enExample) |
| WO (1) | WO1986005698A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10021110B4 (de) * | 1999-05-04 | 2010-06-10 | Medtronic, Inc., Minneapolis | Vorrichtung zum Behindern oder Minimieren des Verkalkens von Aortenklappen |
| DE102019116755A1 (de) * | 2019-06-20 | 2020-12-24 | Wolfgang Herzberg | Implementierbares Verfahren zum Betreiben eines Herzschrittmachers |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0255899B1 (de) * | 1986-07-31 | 1992-07-15 | Werner Prof. Dr.-Ing. Irnich | Frequenzadaptierender Herzschrittmacher |
| IT1214738B (it) * | 1986-11-11 | 1990-01-18 | Sbm Soc Brevetti Medicina | Perfezionamento negli impianti di stimolazione cardiaca mediante pacemaker |
| US4838278A (en) * | 1987-02-26 | 1989-06-13 | Hewlett-Packard Company | Paced QRS complex classifier |
| US4856523A (en) * | 1987-10-08 | 1989-08-15 | Siemens-Pacesetter, Inc. | Rate-responsive pacemaker with automatic mode switching and/or variable hysteresis rate |
| US4920965A (en) * | 1987-11-25 | 1990-05-01 | Medtronic, Inc. | Dual chamber pacemaker with adaptive atrial escape interval |
| US5179949A (en) * | 1990-12-07 | 1993-01-19 | Raul Chirife | Cardiac pacemaker with automatic a-v programming for optimization of left heart a-v interval |
| IT1259358B (it) * | 1992-03-26 | 1996-03-12 | Sorin Biomedica Spa | Dispositivo impiantabile per la rilevazione ed il controllo del tono simpatico-vagale |
| US5275621A (en) * | 1992-04-13 | 1994-01-04 | Medtronic, Inc. | Method and apparatus for terminating tachycardia |
| FR2774916B1 (fr) * | 1998-02-13 | 2000-06-16 | Ela Medical Sa | Dispositif medical implantable actif, notamment stimulateur cardiaque, defibrillateur et/ou cardioverteur, de type multisite |
| DE10028095A1 (de) * | 2000-06-05 | 2001-12-06 | Biotronik Mess & Therapieg | Signalisierungsverfahren für eine implantierbare Herzstimulationsvorrichtung und Herzstimulationsvorrichtung |
| US7231249B2 (en) | 2003-07-24 | 2007-06-12 | Mirowski Family Ventures, L.L.C. | Methods, apparatus, and systems for multiple stimulation from a single stimulator |
| US20050055058A1 (en) | 2003-09-08 | 2005-03-10 | Mower Morton M. | Method and apparatus for intrachamber resynchronization |
| US7130689B1 (en) | 2004-02-24 | 2006-10-31 | Pacesetter, Inc. | Methods and systems for optimizing cardiac pacing intervals for various physiologic factors |
| JP5646157B2 (ja) * | 2009-10-30 | 2014-12-24 | オリンパス株式会社 | 心臓治療装置 |
| US8682432B2 (en) | 2009-10-30 | 2014-03-25 | Olympus Corporation | Cardiac-event processor and heart treatment device |
| JP6050645B2 (ja) * | 2012-10-03 | 2016-12-21 | 日本光電工業株式会社 | 心拍再開の可能性を判断する装置 |
| EP3113033B1 (fr) | 2015-06-29 | 2019-01-09 | Sorin CRM SAS | Système de traitement par stimulation, notamment du nerf vague, par mise en oeuvre d'un modèle de transition d'états |
| EP3111991B1 (fr) | 2015-06-29 | 2020-01-29 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'états autoadaptable en fonction des niveaux physiques ou physiologiques |
| EP3111992B1 (fr) | 2015-06-29 | 2018-08-01 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'état opérant à des résolutions temporelles ou spatiales multiples |
| EP3111990B1 (fr) | 2015-06-29 | 2019-02-27 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'état avec apprentissage préalable |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857399A (en) * | 1970-03-24 | 1974-12-31 | F Zacouto | Heart pacer |
| US3807410A (en) * | 1971-11-19 | 1974-04-30 | American Optical Corp | Adaptive demand pacer |
| US4060090A (en) * | 1976-03-04 | 1977-11-29 | Medtronic, Inc. | Variable P-R interval pacemaker |
| US4312355A (en) * | 1977-01-12 | 1982-01-26 | Medtronic B.V. | Heart pacemaker |
| EP0007189B1 (en) * | 1978-06-23 | 1982-06-02 | Vitafin N.V. | Physiologically adaptive cardiac pacemaker |
| US4305396A (en) * | 1979-04-16 | 1981-12-15 | Vitatron Medical B.V. | Rate adaptive pacemaker and method of cardiac pacing |
| US4373531A (en) * | 1979-04-16 | 1983-02-15 | Vitafin N.V. | Apparatus for physiological stimulation and detection of evoked response |
| US4313442A (en) * | 1980-07-21 | 1982-02-02 | Cardiac Pacemakers, Inc. | Atrial rate sensitive cardiac pacer apparatus |
| AU541479B2 (en) * | 1980-10-14 | 1985-01-10 | Medtronic, Inc. | Heart pacemeker with separate a-v intervals for a trial synchronous and atrial-ventricular sequential pacing modes |
| US4401119A (en) * | 1981-02-17 | 1983-08-30 | Medtronic, Inc. | Prolongation of timing intervals in response to ectopic heart beats in atrial and ventricular pacemakers |
| DE3115124A1 (de) * | 1981-04-10 | 1982-11-04 | Biotronik Meß- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin, 1000 Berlin | "herzschrittmacher" |
| US4527568A (en) * | 1983-12-27 | 1985-07-09 | Vitafin N.V. | Dual chamber pacer with alternative rate adaptive means and method |
-
1985
- 1985-10-11 EP EP85905293A patent/EP0220194B1/en not_active Expired - Lifetime
- 1985-10-11 JP JP60504645A patent/JPS63500845A/ja active Granted
- 1985-10-11 WO PCT/US1985/002010 patent/WO1986005698A1/en not_active Ceased
- 1985-10-11 DE DE3587786T patent/DE3587786T2/de not_active Expired - Lifetime
-
1986
- 1986-02-11 CA CA000501554A patent/CA1272763A/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10021110B4 (de) * | 1999-05-04 | 2010-06-10 | Medtronic, Inc., Minneapolis | Vorrichtung zum Behindern oder Minimieren des Verkalkens von Aortenklappen |
| DE102019116755A1 (de) * | 2019-06-20 | 2020-12-24 | Wolfgang Herzberg | Implementierbares Verfahren zum Betreiben eines Herzschrittmachers |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0220194A4 (en) | 1988-09-07 |
| EP0220194B1 (en) | 1994-03-30 |
| EP0220194A1 (en) | 1987-05-06 |
| DE3587786D1 (de) | 1994-05-05 |
| WO1986005698A1 (en) | 1986-10-09 |
| CA1272763A (en) | 1990-08-14 |
| JPS63500845A (ja) | 1988-03-31 |
| JPH0566826B2 (enExample) | 1993-09-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3587786T2 (de) | Messung des herzschlagintervalls eines stimulierten herzes, sich anpassender herzschrittmacher und betriebsart. | |
| DE69527570T2 (de) | Zweikammer-Herzschrittmacher mit gezwungener atro-ventrikulären Synchronität | |
| DE69531115T2 (de) | Herzschrittmacher mit Detektion einer erfolgreichen Stimulation des Ventrikel und Suche nach dem Stimulation-Schwellenwert | |
| DE69510448T2 (de) | Vorrichtung eines zweikammerherzschrittmachers | |
| DE3856343T2 (de) | Detektionsschaltung zur bestimmung des detektionsabstandes für implantierte elektromedizinische geräte | |
| DE68919425T2 (de) | Schrittmacher mit verbesserter automatischer Ausgangsregelung. | |
| DE69225118T2 (de) | Durch Reizung von einem implantierten Skelettmuskelstransplantat arbeitendes Arrhythmiekontrollgerät | |
| DE60223836T2 (de) | System für bi-ventrikuläres gleichzeitiges schrittmachen | |
| DE69600596T2 (de) | Zweikammer-schrittmacher-anordnung zur kontinuierlichen regelung des av zeitintervalles mit dem ziel, optimierte stimulierung zur behandlung von kardiomyopathien zu erreichen | |
| DE3852607T3 (de) | Frequenzabhängiger Schrittmacher mit variabler Hysteresefrequenz. | |
| DE60222071T2 (de) | Implantierbares Herzschrittmachersystem mit Kalibrierung für automatische Erregungsbestätigung | |
| DE68927447T2 (de) | Frequenz-empfindlicher Herzschrittmacher | |
| DE60122820T2 (de) | Vorrichtung zur Verringerung der Effekte von evozierten Potentialen bei Polarisationsmessungen in einem Herzschrittmachersystem mit automatischer Erfassung des Einfanges | |
| DE69333006T2 (de) | Implantierbarer herzschrittmacher mit system zur automatischen erkennung einer erfolgreichen stimulation | |
| DE69307509T2 (de) | Vorrichtung zur behandlung von herzfehlern | |
| DE69930570T2 (de) | Zweistellen-Herzschrittmachersystem mit automatischer Pulsausgangseinstellung | |
| DE60201679T2 (de) | System zur regelung des herzrhythmus mit auswahl der elektroden | |
| DE69919983T2 (de) | System zum einleiten von herzkammerflimmern unter verwendung von nahfeldwellenabtastung | |
| DE60222183T2 (de) | Implantierbares medizinisches gerät mit autosensitivitätsalgorithmus zur steuerung der detektion von herzsignalen | |
| DE60114507T2 (de) | Verfahren und Vorrichtung zur biventrikulären Stimulation und zur Überwachung des Einfanges | |
| DE60107609T2 (de) | Zweikammer-Herzschrittmachersystem mit einer sich zeitlich anpassenden A-V Verzögerung | |
| DE69327447T2 (de) | Implantierbarer Zweikammer-Herzschrittmacher mit einer sich anpassenden A-V Verzögerung um den Zusammenfall von Herzkammer-Reizungpulsen und Klopfen zu vermeiden | |
| EP0063097B1 (de) | Herzschrittmacher | |
| DE60220751T2 (de) | Herzschrittmacher mit verbesserter Einfangsbestätigung | |
| DE69325772T2 (de) | Implantierbarer Herzschrittmacher mit anpassbarem AV-Intervall zur Behandlung von Kardiomyopathie |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PACESETTER AB, SOLNA, SE |
|
| 8328 | Change in the person/name/address of the agent |
Free format text: BLUMBACH, KRAMER & PARTNER, 81245 MUENCHEN |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PACESETTER AB, JAERFAELLA, SE |
|
| 8365 | Fully valid after opposition proceedings | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KRAMER - BARSKE - SCHMIDTCHEN, 81245 MUENCHEN |