JPH0566826B2 - - Google Patents
Info
- Publication number
- JPH0566826B2 JPH0566826B2 JP60504645A JP50464585A JPH0566826B2 JP H0566826 B2 JPH0566826 B2 JP H0566826B2 JP 60504645 A JP60504645 A JP 60504645A JP 50464585 A JP50464585 A JP 50464585A JP H0566826 B2 JPH0566826 B2 JP H0566826B2
- Authority
- JP
- Japan
- Prior art keywords
- wave
- interval
- pacemaker
- atrial
- pulse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000747 cardiac effect Effects 0.000 description 106
- 238000001514 detection method Methods 0.000 description 101
- 230000000638 stimulation Effects 0.000 description 101
- 230000001746 atrial effect Effects 0.000 description 98
- 238000005259 measurement Methods 0.000 description 79
- 238000010586 diagram Methods 0.000 description 54
- 230000006870 function Effects 0.000 description 48
- 210000002837 heart atrium Anatomy 0.000 description 48
- 230000004044 response Effects 0.000 description 46
- 230000002861 ventricular Effects 0.000 description 37
- 238000000034 method Methods 0.000 description 28
- 230000028161 membrane depolarization Effects 0.000 description 24
- 230000036279 refractory period Effects 0.000 description 24
- 238000001615 p wave Methods 0.000 description 22
- 239000008186 active pharmaceutical agent Substances 0.000 description 21
- 239000008280 blood Substances 0.000 description 20
- 210000004369 blood Anatomy 0.000 description 20
- 238000012545 processing Methods 0.000 description 17
- 230000008859 change Effects 0.000 description 16
- 239000004020 conductor Substances 0.000 description 13
- 230000008602 contraction Effects 0.000 description 13
- 230000004213 regulation of atrial cardiomyocyte membrane depolarization Effects 0.000 description 12
- 230000009977 dual effect Effects 0.000 description 11
- 230000008569 process Effects 0.000 description 11
- 210000005245 right atrium Anatomy 0.000 description 11
- 230000003044 adaptive effect Effects 0.000 description 10
- 230000001276 controlling effect Effects 0.000 description 10
- 230000001965 increasing effect Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 230000034225 regulation of ventricular cardiomyocyte membrane depolarization Effects 0.000 description 9
- 230000004936 stimulating effect Effects 0.000 description 8
- 238000012935 Averaging Methods 0.000 description 7
- 230000000903 blocking effect Effects 0.000 description 7
- 210000005241 right ventricle Anatomy 0.000 description 7
- 230000002269 spontaneous effect Effects 0.000 description 7
- 230000001960 triggered effect Effects 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 238000000718 qrs complex Methods 0.000 description 6
- 230000001105 regulatory effect Effects 0.000 description 6
- 210000001992 atrioventricular node Anatomy 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 5
- 210000005240 left ventricle Anatomy 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 230000033764 rhythmic process Effects 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 210000005242 cardiac chamber Anatomy 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 238000009499 grossing Methods 0.000 description 4
- 210000005246 left atrium Anatomy 0.000 description 4
- 210000001013 sinoatrial node Anatomy 0.000 description 4
- 102100026827 Protein associated with UVRAG as autophagy enhancer Human genes 0.000 description 3
- 101710102978 Protein associated with UVRAG as autophagy enhancer Proteins 0.000 description 3
- 230000005856 abnormality Effects 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 210000001008 atrial appendage Anatomy 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 210000001147 pulmonary artery Anatomy 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 210000000709 aorta Anatomy 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000007914 intraventricular administration Methods 0.000 description 2
- 238000012886 linear function Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 238000004904 shortening Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- SPBWHPXCWJLQRU-FITJORAGSA-N 4-amino-8-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide Chemical compound C12=NC=NC(N)=C2C(=O)C(C(=O)N)=CN1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O SPBWHPXCWJLQRU-FITJORAGSA-N 0.000 description 1
- 206010003671 Atrioventricular Block Diseases 0.000 description 1
- 208000010271 Heart Block Diseases 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 210000001765 aortic valve Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000004413 cardiac myocyte Anatomy 0.000 description 1
- 230000000763 evoking effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000004115 mitral valve Anatomy 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 210000003102 pulmonary valve Anatomy 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 239000013643 reference control Substances 0.000 description 1
- 230000002336 repolarization Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 210000002620 vena cava superior Anatomy 0.000 description 1
- 230000003245 working effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/716,831 US4712555A (en) | 1984-10-19 | 1985-03-27 | Physiologically responsive pacemaker and method of adjusting the pacing interval thereof |
| US716831 | 1985-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63500845A JPS63500845A (ja) | 1988-03-31 |
| JPH0566826B2 true JPH0566826B2 (enExample) | 1993-09-22 |
Family
ID=24879623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60504645A Granted JPS63500845A (ja) | 1985-03-27 | 1985-10-11 | 心臓ペースメーカの整調間隔自動調節用生理学的センサ |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0220194B1 (enExample) |
| JP (1) | JPS63500845A (enExample) |
| CA (1) | CA1272763A (enExample) |
| DE (1) | DE3587786T2 (enExample) |
| WO (1) | WO1986005698A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0255899B1 (de) * | 1986-07-31 | 1992-07-15 | Werner Prof. Dr.-Ing. Irnich | Frequenzadaptierender Herzschrittmacher |
| IT1214738B (it) * | 1986-11-11 | 1990-01-18 | Sbm Soc Brevetti Medicina | Perfezionamento negli impianti di stimolazione cardiaca mediante pacemaker |
| US4838278A (en) * | 1987-02-26 | 1989-06-13 | Hewlett-Packard Company | Paced QRS complex classifier |
| US4856523A (en) * | 1987-10-08 | 1989-08-15 | Siemens-Pacesetter, Inc. | Rate-responsive pacemaker with automatic mode switching and/or variable hysteresis rate |
| US4920965A (en) * | 1987-11-25 | 1990-05-01 | Medtronic, Inc. | Dual chamber pacemaker with adaptive atrial escape interval |
| US5179949A (en) * | 1990-12-07 | 1993-01-19 | Raul Chirife | Cardiac pacemaker with automatic a-v programming for optimization of left heart a-v interval |
| IT1259358B (it) * | 1992-03-26 | 1996-03-12 | Sorin Biomedica Spa | Dispositivo impiantabile per la rilevazione ed il controllo del tono simpatico-vagale |
| US5275621A (en) * | 1992-04-13 | 1994-01-04 | Medtronic, Inc. | Method and apparatus for terminating tachycardia |
| FR2774916B1 (fr) * | 1998-02-13 | 2000-06-16 | Ela Medical Sa | Dispositif medical implantable actif, notamment stimulateur cardiaque, defibrillateur et/ou cardioverteur, de type multisite |
| GB2349824B (en) * | 1999-05-04 | 2003-03-12 | Medtronic Inc | Apparatus for inhibiting or minimizing calcification of aortic valves |
| DE10028095A1 (de) * | 2000-06-05 | 2001-12-06 | Biotronik Mess & Therapieg | Signalisierungsverfahren für eine implantierbare Herzstimulationsvorrichtung und Herzstimulationsvorrichtung |
| US7231249B2 (en) | 2003-07-24 | 2007-06-12 | Mirowski Family Ventures, L.L.C. | Methods, apparatus, and systems for multiple stimulation from a single stimulator |
| US20050055058A1 (en) | 2003-09-08 | 2005-03-10 | Mower Morton M. | Method and apparatus for intrachamber resynchronization |
| US7130689B1 (en) | 2004-02-24 | 2006-10-31 | Pacesetter, Inc. | Methods and systems for optimizing cardiac pacing intervals for various physiologic factors |
| JP5646157B2 (ja) * | 2009-10-30 | 2014-12-24 | オリンパス株式会社 | 心臓治療装置 |
| US8682432B2 (en) | 2009-10-30 | 2014-03-25 | Olympus Corporation | Cardiac-event processor and heart treatment device |
| JP6050645B2 (ja) * | 2012-10-03 | 2016-12-21 | 日本光電工業株式会社 | 心拍再開の可能性を判断する装置 |
| EP3113033B1 (fr) | 2015-06-29 | 2019-01-09 | Sorin CRM SAS | Système de traitement par stimulation, notamment du nerf vague, par mise en oeuvre d'un modèle de transition d'états |
| EP3111991B1 (fr) | 2015-06-29 | 2020-01-29 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'états autoadaptable en fonction des niveaux physiques ou physiologiques |
| EP3111992B1 (fr) | 2015-06-29 | 2018-08-01 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'état opérant à des résolutions temporelles ou spatiales multiples |
| EP3111990B1 (fr) | 2015-06-29 | 2019-02-27 | Sorin CRM SAS | Système de traitement par stimulation, notamment de stimulation du nerf vague, par mise en oeuvre d'un modèle de transition d'état avec apprentissage préalable |
| DE102019116755A1 (de) * | 2019-06-20 | 2020-12-24 | Wolfgang Herzberg | Implementierbares Verfahren zum Betreiben eines Herzschrittmachers |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857399A (en) * | 1970-03-24 | 1974-12-31 | F Zacouto | Heart pacer |
| US3807410A (en) * | 1971-11-19 | 1974-04-30 | American Optical Corp | Adaptive demand pacer |
| US4060090A (en) * | 1976-03-04 | 1977-11-29 | Medtronic, Inc. | Variable P-R interval pacemaker |
| US4312355A (en) * | 1977-01-12 | 1982-01-26 | Medtronic B.V. | Heart pacemaker |
| EP0007189B1 (en) * | 1978-06-23 | 1982-06-02 | Vitafin N.V. | Physiologically adaptive cardiac pacemaker |
| US4305396A (en) * | 1979-04-16 | 1981-12-15 | Vitatron Medical B.V. | Rate adaptive pacemaker and method of cardiac pacing |
| US4373531A (en) * | 1979-04-16 | 1983-02-15 | Vitafin N.V. | Apparatus for physiological stimulation and detection of evoked response |
| US4313442A (en) * | 1980-07-21 | 1982-02-02 | Cardiac Pacemakers, Inc. | Atrial rate sensitive cardiac pacer apparatus |
| AU541479B2 (en) * | 1980-10-14 | 1985-01-10 | Medtronic, Inc. | Heart pacemeker with separate a-v intervals for a trial synchronous and atrial-ventricular sequential pacing modes |
| US4401119A (en) * | 1981-02-17 | 1983-08-30 | Medtronic, Inc. | Prolongation of timing intervals in response to ectopic heart beats in atrial and ventricular pacemakers |
| DE3115124A1 (de) * | 1981-04-10 | 1982-11-04 | Biotronik Meß- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin, 1000 Berlin | "herzschrittmacher" |
| US4527568A (en) * | 1983-12-27 | 1985-07-09 | Vitafin N.V. | Dual chamber pacer with alternative rate adaptive means and method |
-
1985
- 1985-10-11 EP EP85905293A patent/EP0220194B1/en not_active Expired - Lifetime
- 1985-10-11 JP JP60504645A patent/JPS63500845A/ja active Granted
- 1985-10-11 WO PCT/US1985/002010 patent/WO1986005698A1/en not_active Ceased
- 1985-10-11 DE DE3587786T patent/DE3587786T2/de not_active Expired - Lifetime
-
1986
- 1986-02-11 CA CA000501554A patent/CA1272763A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0220194A4 (en) | 1988-09-07 |
| EP0220194B1 (en) | 1994-03-30 |
| EP0220194A1 (en) | 1987-05-06 |
| DE3587786T2 (de) | 1995-06-01 |
| DE3587786D1 (de) | 1994-05-05 |
| WO1986005698A1 (en) | 1986-10-09 |
| CA1272763A (en) | 1990-08-14 |
| JPS63500845A (ja) | 1988-03-31 |
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