DE3587511D1 - Aromatische diole. - Google Patents

Aromatische diole.

Info

Publication number
DE3587511D1
DE3587511D1 DE8989117732T DE3587511T DE3587511D1 DE 3587511 D1 DE3587511 D1 DE 3587511D1 DE 8989117732 T DE8989117732 T DE 8989117732T DE 3587511 T DE3587511 T DE 3587511T DE 3587511 D1 DE3587511 D1 DE 3587511D1
Authority
DE
Germany
Prior art keywords
sup
alkyl
compounds
diole
aromatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989117732T
Other languages
English (en)
Other versions
DE3587511T2 (de
Inventor
John Kitchin
Peter Clive Cherry
Adrian John Pipe
Andrew James Crame
Alan David Borthwick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848410456A external-priority patent/GB8410456D0/en
Priority claimed from GB858503975A external-priority patent/GB8503975D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE3587511D1 publication Critical patent/DE3587511D1/de
Application granted granted Critical
Publication of DE3587511T2 publication Critical patent/DE3587511T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
DE89117732T 1984-04-24 1985-04-24 Aromatische Diole. Expired - Fee Related DE3587511T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848410456A GB8410456D0 (en) 1984-04-24 1984-04-24 Chemical compounds
GB858503975A GB8503975D0 (en) 1985-02-15 1985-02-15 Chemical compounds

Publications (2)

Publication Number Publication Date
DE3587511D1 true DE3587511D1 (de) 1993-09-09
DE3587511T2 DE3587511T2 (de) 1993-11-18

Family

ID=26287645

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8585302854T Expired - Fee Related DE3579189D1 (de) 1984-04-24 1985-04-24 Heterocyclische aminoverbindungen.
DE89117732T Expired - Fee Related DE3587511T2 (de) 1984-04-24 1985-04-24 Aromatische Diole.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8585302854T Expired - Fee Related DE3579189D1 (de) 1984-04-24 1985-04-24 Heterocyclische aminoverbindungen.

Country Status (21)

Country Link
US (1) US4880801A (de)
EP (2) EP0162593B1 (de)
JP (2) JPH02270819A (de)
KR (1) KR920003065B1 (de)
AT (1) ATE55605T1 (de)
AU (1) AU577367B2 (de)
CA (1) CA1256111A (de)
CS (1) CS402491A3 (de)
CY (2) CY1532A (de)
DE (2) DE3579189D1 (de)
DK (2) DK160556C (de)
ES (2) ES8607311A1 (de)
FI (1) FI84069C (de)
GB (3) GB2201414B (de)
GR (1) GR850993B (de)
HK (2) HK42890A (de)
IL (1) IL75011A (de)
MX (1) MX9203233A (de)
NZ (1) NZ211885A (de)
PT (1) PT80344B (de)
SG (2) SG23590G (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8526210D0 (en) * 1985-10-23 1985-11-27 Glaxo Group Ltd Chemical compounds
GB8526209D0 (en) * 1985-10-23 1985-11-27 Glaxo Group Ltd Chemical process
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8828032D0 (en) * 1988-12-01 1989-01-05 Glaxo Group Ltd Medicaments
GB9012469D0 (en) * 1990-06-05 1990-07-25 Glaxo Group Ltd Medicaments
GB9119466D0 (en) * 1991-09-12 1991-10-23 Glaxo Group Ltd Chemical compounds
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
CA2522666A1 (en) * 2003-04-18 2004-10-28 Pharmacia & Upjohn Company Llc Combination therapies for chronic obstructive pulmonary disease (copd)
GB2503187A (en) * 2011-09-15 2013-12-25 Univ Sussex Composition for use in the treatment of neurodevelopmental disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2485539A1 (fr) * 1980-06-26 1981-12-31 Sori Soc Rech Ind Nouveau derive de pyranno-indole, son procede de preparation et son application en therapeutique
IL70034A0 (en) * 1982-10-25 1984-01-31 Glaxo Group Ltd Heterocyclic amino compounds,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK184085A (da) 1985-10-25
FI84069C (fi) 1991-10-10
DK160556B (da) 1991-03-25
DK160824C (da) 1991-10-07
KR920003065B1 (ko) 1992-04-13
GB2201414B (en) 1988-12-29
HK42890A (en) 1990-06-08
GB8728949D0 (en) 1988-01-27
FI851611L (fi) 1985-10-25
EP0162593A1 (de) 1985-11-27
SG23590G (en) 1990-07-13
GR850993B (de) 1985-11-25
KR850007259A (ko) 1985-12-02
AU4166785A (en) 1985-10-31
CS402491A3 (en) 1992-10-14
PT80344B (pt) 1987-09-30
GB2201414A (en) 1988-09-01
IL75011A (en) 1990-02-09
EP0162593B1 (de) 1990-08-16
ES551509A0 (es) 1988-02-01
ES542516A0 (es) 1986-06-16
EP0359290B1 (de) 1993-08-04
HK112093A (en) 1993-10-29
SG12293G (en) 1993-04-16
JPH02270878A (ja) 1990-11-05
NZ211885A (en) 1988-09-29
AU577367B2 (en) 1988-09-22
ES8607311A1 (es) 1986-06-16
FI84069B (fi) 1991-06-28
GB8510449D0 (en) 1985-05-30
GB2157691B (en) 1989-07-05
DK160556C (da) 1991-09-02
GB2157691A (en) 1985-10-30
DE3579189D1 (de) 1990-09-20
DE3587511T2 (de) 1993-11-18
PT80344A (en) 1985-05-01
CA1256111A (en) 1989-06-20
DK141590D0 (da) 1990-06-08
DK141590A (da) 1990-06-08
GB8802949D0 (en) 1988-03-09
ES8801545A1 (es) 1988-02-01
MX9203233A (es) 1992-07-01
ATE55605T1 (de) 1990-09-15
DK184085D0 (da) 1985-04-24
US4880801A (en) 1989-11-14
FI851611A0 (fi) 1985-04-24
JPH02270819A (ja) 1990-11-05
DK160824B (da) 1991-04-22
CY1532A (en) 1990-11-16
CY1695A (en) 1994-01-14
EP0359290A1 (de) 1990-03-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee