DE3579189D1 - Heterocyclische aminoverbindungen. - Google Patents

Heterocyclische aminoverbindungen.

Info

Publication number
DE3579189D1
DE3579189D1 DE8585302854T DE3579189T DE3579189D1 DE 3579189 D1 DE3579189 D1 DE 3579189D1 DE 8585302854 T DE8585302854 T DE 8585302854T DE 3579189 T DE3579189 T DE 3579189T DE 3579189 D1 DE3579189 D1 DE 3579189D1
Authority
DE
Germany
Prior art keywords
sup
compounds
alkyl
amino compounds
heterocyclic amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585302854T
Other languages
English (en)
Inventor
John Kitchin
Peter Clive Cherry
Adrian John Pipe
Andrew James Crame
Alan David Borthwick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848410456A external-priority patent/GB8410456D0/en
Priority claimed from GB858503975A external-priority patent/GB8503975D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3579189D1 publication Critical patent/DE3579189D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Luminescent Compositions (AREA)
DE8585302854T 1984-04-24 1985-04-24 Heterocyclische aminoverbindungen. Expired - Fee Related DE3579189D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848410456A GB8410456D0 (en) 1984-04-24 1984-04-24 Chemical compounds
GB858503975A GB8503975D0 (en) 1985-02-15 1985-02-15 Chemical compounds

Publications (1)

Publication Number Publication Date
DE3579189D1 true DE3579189D1 (de) 1990-09-20

Family

ID=26287645

Family Applications (2)

Application Number Title Priority Date Filing Date
DE89117732T Expired - Fee Related DE3587511T2 (de) 1984-04-24 1985-04-24 Aromatische Diole.
DE8585302854T Expired - Fee Related DE3579189D1 (de) 1984-04-24 1985-04-24 Heterocyclische aminoverbindungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE89117732T Expired - Fee Related DE3587511T2 (de) 1984-04-24 1985-04-24 Aromatische Diole.

Country Status (21)

Country Link
US (1) US4880801A (de)
EP (2) EP0359290B1 (de)
JP (2) JPH02270878A (de)
KR (1) KR920003065B1 (de)
AT (1) ATE55605T1 (de)
AU (1) AU577367B2 (de)
CA (1) CA1256111A (de)
CS (1) CS402491A3 (de)
CY (2) CY1532A (de)
DE (2) DE3587511T2 (de)
DK (2) DK160556C (de)
ES (2) ES8607311A1 (de)
FI (1) FI84069C (de)
GB (3) GB2157691B (de)
GR (1) GR850993B (de)
HK (2) HK42890A (de)
IL (1) IL75011A (de)
MX (1) MX9203233A (de)
NZ (1) NZ211885A (de)
PT (1) PT80344B (de)
SG (2) SG23590G (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8526210D0 (en) * 1985-10-23 1985-11-27 Glaxo Group Ltd Chemical compounds
GB8526209D0 (en) * 1985-10-23 1985-11-27 Glaxo Group Ltd Chemical process
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8828032D0 (en) * 1988-12-01 1989-01-05 Glaxo Group Ltd Medicaments
GB9012469D0 (en) * 1990-06-05 1990-07-25 Glaxo Group Ltd Medicaments
GB9119466D0 (en) * 1991-09-12 1991-10-23 Glaxo Group Ltd Chemical compounds
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
CA2522666A1 (en) * 2003-04-18 2004-10-28 Pharmacia & Upjohn Company Llc Combination therapies for chronic obstructive pulmonary disease (copd)
GB2503187A (en) * 2011-09-15 2013-12-25 Univ Sussex Composition for use in the treatment of neurodevelopmental disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2485539A1 (fr) * 1980-06-26 1981-12-31 Sori Soc Rech Ind Nouveau derive de pyranno-indole, son procede de preparation et son application en therapeutique
IL70034A0 (en) * 1982-10-25 1984-01-31 Glaxo Group Ltd Heterocyclic amino compounds,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CS402491A3 (en) 1992-10-14
ES542516A0 (es) 1986-06-16
CY1532A (en) 1990-11-16
EP0359290B1 (de) 1993-08-04
JPH02270819A (ja) 1990-11-05
KR920003065B1 (ko) 1992-04-13
DE3587511D1 (de) 1993-09-09
DE3587511T2 (de) 1993-11-18
DK184085A (da) 1985-10-25
GB2201414A (en) 1988-09-01
ES8607311A1 (es) 1986-06-16
HK112093A (en) 1993-10-29
GR850993B (de) 1985-11-25
AU4166785A (en) 1985-10-31
GB2157691A (en) 1985-10-30
AU577367B2 (en) 1988-09-22
ES8801545A1 (es) 1988-02-01
DK184085D0 (da) 1985-04-24
DK160556B (da) 1991-03-25
FI84069C (fi) 1991-10-10
DK160556C (da) 1991-09-02
MX9203233A (es) 1992-07-01
DK141590A (da) 1990-06-08
SG23590G (en) 1990-07-13
JPH02270878A (ja) 1990-11-05
HK42890A (en) 1990-06-08
GB8802949D0 (en) 1988-03-09
PT80344B (pt) 1987-09-30
GB2201414B (en) 1988-12-29
DK160824C (da) 1991-10-07
PT80344A (en) 1985-05-01
DK141590D0 (da) 1990-06-08
GB8728949D0 (en) 1988-01-27
EP0162593B1 (de) 1990-08-16
ES551509A0 (es) 1988-02-01
GB8510449D0 (en) 1985-05-30
ATE55605T1 (de) 1990-09-15
GB2157691B (en) 1989-07-05
IL75011A (en) 1990-02-09
DK160824B (da) 1991-04-22
SG12293G (en) 1993-04-16
FI84069B (fi) 1991-06-28
FI851611A0 (fi) 1985-04-24
NZ211885A (en) 1988-09-29
FI851611L (fi) 1985-10-25
CY1695A (en) 1994-01-14
CA1256111A (en) 1989-06-20
EP0162593A1 (de) 1985-11-27
US4880801A (en) 1989-11-14
EP0359290A1 (de) 1990-03-21
KR850007259A (ko) 1985-12-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee