DE3587510D1 - Geraet zur messung von endotoxin. - Google Patents
Geraet zur messung von endotoxin.Info
- Publication number
- DE3587510D1 DE3587510D1 DE8989114580T DE3587510T DE3587510D1 DE 3587510 D1 DE3587510 D1 DE 3587510D1 DE 8989114580 T DE8989114580 T DE 8989114580T DE 3587510 T DE3587510 T DE 3587510T DE 3587510 D1 DE3587510 D1 DE 3587510D1
- Authority
- DE
- Germany
- Prior art keywords
- time
- gelation
- light amount
- transmitted light
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
- G01N21/83—Turbidimetric titration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/04—Batch operation; multisample devices
- G01N2201/0407—Batch operation; multisample devices with multiple optical units, e.g. one per sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13244584A JPS6111641A (ja) | 1984-06-27 | 1984-06-27 | エンドトキシンの測定方法および装置 |
JP28161684A JPS61159162A (ja) | 1984-12-28 | 1984-12-28 | エンドトキシンの測定方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3587510D1 true DE3587510D1 (de) | 1993-09-09 |
DE3587510T2 DE3587510T2 (de) | 1994-03-03 |
Family
ID=26467021
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89114580T Expired - Fee Related DE3587510T2 (de) | 1984-06-27 | 1985-06-25 | Gerät zur Messung von Endotoxin. |
DE8585107877T Expired - Lifetime DE3586075D1 (de) | 1984-06-27 | 1985-06-25 | Verfahren zur bestimmung von endotoxin. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585107877T Expired - Lifetime DE3586075D1 (de) | 1984-06-27 | 1985-06-25 | Verfahren zur bestimmung von endotoxin. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4740460A (de) |
EP (2) | EP0347951B1 (de) |
AT (2) | ATE92630T1 (de) |
DE (2) | DE3587510T2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4936682A (en) * | 1987-08-11 | 1990-06-26 | Associates Of Cape Cod, Inc. | Instrument for independently and kinetically measuring light transpassion through a plurality of samples |
JPH0715474B2 (ja) * | 1988-02-27 | 1995-02-22 | 和光純薬工業株式会社 | エンドトキシンの測定法 |
DE68916714T2 (de) * | 1988-07-05 | 1995-01-12 | Wako Pure Chem Ind Ltd | Verfahren zur Bestimmung von Endotoxinen. |
US5342785A (en) * | 1988-07-05 | 1994-08-30 | Tanabe Seiyaku Co., Ltd. | Method for determining pyrogen content |
US5306641A (en) * | 1990-07-27 | 1994-04-26 | Saccocio Edward J | Apparatus and method for determining gel rate of polymerizable compositions |
US5167145B1 (en) * | 1990-09-19 | 2000-05-23 | David M Butler | Measurement of blood coagulation time using infrared electromagnetic energy |
US5522255A (en) | 1993-08-31 | 1996-06-04 | Boehringer Mannheim Corporation | Fluid dose, flow and coagulation sensor for medical instrument |
US5526111A (en) * | 1993-08-31 | 1996-06-11 | Boehringer Mannheim Corporation | Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control |
WO1995014932A1 (fr) * | 1993-11-22 | 1995-06-01 | Seikagaku Corporation | Procede de dosage d'une substance reagissant avec un reactif de limulus |
US5637474A (en) * | 1994-10-31 | 1997-06-10 | Wako Pure Chemical Industries, Ltd. | Process for measuring amount of endotoxin or (1→3)-β-D-glucan by kinetic turbidimetric method |
US6118541A (en) * | 1998-04-13 | 2000-09-12 | Dade Behring Inc. | Method to determine the effectiveness of a chemical mixing system |
CN1296714C (zh) * | 2003-04-09 | 2007-01-24 | 中国科学院大连化学物理研究所 | 测定鲎试剂灵敏度的方法 |
EP1680670A4 (de) * | 2003-11-07 | 2008-01-16 | Cambrex Bio Science Walkersvil | Online-vorrichtung und verfahren zur bestimmung von endotoxin-niveaus |
CN100383528C (zh) * | 2004-07-02 | 2008-04-23 | 中国科学院大连化学物理研究所 | 一种通过测定浊度值来进行细菌内毒素检查的方法 |
WO2008132905A1 (ja) * | 2007-04-20 | 2008-11-06 | Wako Pure Chemical Industries, Ltd. | 微量検体測定用硝子セルバイアル |
US20100129260A1 (en) * | 2007-05-01 | 2010-05-27 | Yoshiaki Shirasawa | Gelation measuring apparatus and sample cell |
JP5188311B2 (ja) * | 2008-07-30 | 2013-04-24 | 興和株式会社 | 生物由来の生理活性物質の測定方法及び測定装置 |
US8507282B2 (en) * | 2009-03-13 | 2013-08-13 | Kowa Company, Ltd. | Method for measuring physiologically active substance of biological origin, program for implementing the same, and apparatus for measuring physiologically active substance of biological origin |
US20140295477A1 (en) * | 2011-09-01 | 2014-10-02 | Fresenius Medical Care Holdings, Inc | Kit For Sampling And Detection Of Endotoxin In Aqueous Solution |
CN104215745A (zh) * | 2014-09-21 | 2014-12-17 | 四川制药制剂有限公司 | 注射用盐酸头孢替安中细菌内毒素含量的测定方法 |
US11892397B2 (en) * | 2017-10-17 | 2024-02-06 | Board Of Regents, The University Of Texas System | Endotoxin testing assay and method of same |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3458287A (en) * | 1965-04-29 | 1969-07-29 | Medical Laboratory Automation | Method and means of determining endpoint times in blood clotting tests |
US4038029A (en) * | 1976-01-20 | 1977-07-26 | Worthington Biochemical Corporation | Limulus lysate turbidity test for pyrogens |
FR2344841A1 (fr) * | 1976-03-16 | 1977-10-14 | Ucc Union Chimique Cont | Correcteur electronique du temps de coagulation du sang |
US4268171A (en) * | 1977-07-18 | 1981-05-19 | Beckman Instruments, Inc. | Method determining concentration in rate nephelometric immunochemical analysis |
JPS54108693A (en) * | 1978-02-14 | 1979-08-25 | Mitsubishi Chem Ind | Method and device for optically measuring antigennantibody reaction |
US4205954A (en) * | 1978-05-26 | 1980-06-03 | Warner-Lambert Company | Kinetic latex agglutinometry |
IT1105662B (it) * | 1978-09-07 | 1985-11-04 | Salus Istituto Diagnostico Di | Apparecchiatura per studiare e fenomeni della emocoagulazione e dell'aggregazione delle piastrine |
DE3005923A1 (de) * | 1980-02-16 | 1981-09-03 | Compur-Electronic GmbH, 8000 München | Photometrisches verfahren und photometrische vorrichtung zur bestimmung von reaktionsablaeufen |
IT1208062B (it) * | 1981-03-23 | 1989-06-06 | Croce F Dr Salus Ricerca | Dei fenomeni di emocoagulazione, dispositivo di rivelazione ottica concentrazione, ed aggregazione delle piastrine o simili. |
JPS589050A (ja) * | 1981-07-10 | 1983-01-19 | Japan Organo Co Ltd | エンドトキシン含有量の測定方法および装置 |
WO1983000228A1 (en) * | 1981-07-11 | 1983-01-20 | Siegfried Jochimsen | Apparatus for measuring the blood clotting time and method for taking and measuring the time |
JPS58135459A (ja) * | 1982-02-05 | 1983-08-12 | Dai Ichi Seiyaku Co Ltd | エンドトキシンの定量法 |
US4454752A (en) * | 1982-06-21 | 1984-06-19 | Medical Laboratory Automation, Inc. | Test circuit for use in coagulation instrument |
JPS5942451A (ja) * | 1982-09-01 | 1984-03-09 | Japan Organo Co Ltd | エンドトキシンの定量分析法 |
-
1985
- 1985-06-25 DE DE89114580T patent/DE3587510T2/de not_active Expired - Fee Related
- 1985-06-25 DE DE8585107877T patent/DE3586075D1/de not_active Expired - Lifetime
- 1985-06-25 AT AT89114580T patent/ATE92630T1/de not_active IP Right Cessation
- 1985-06-25 AT AT85107877T patent/ATE76507T1/de not_active IP Right Cessation
- 1985-06-25 EP EP89114580A patent/EP0347951B1/de not_active Expired - Lifetime
- 1985-06-25 EP EP85107877A patent/EP0173021B1/de not_active Expired
- 1985-06-26 US US06/748,805 patent/US4740460A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0347951B1 (de) | 1993-08-04 |
DE3586075D1 (de) | 1992-06-25 |
DE3587510T2 (de) | 1994-03-03 |
EP0173021A2 (de) | 1986-03-05 |
EP0173021A3 (en) | 1986-10-08 |
EP0347951A3 (en) | 1990-06-06 |
EP0173021B1 (de) | 1992-05-20 |
EP0347951A2 (de) | 1989-12-27 |
US4740460A (en) | 1988-04-26 |
ATE76507T1 (de) | 1992-06-15 |
ATE92630T1 (de) | 1993-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |