DE3586536D1 - Monoklonaler antikoerper gegen ein cytotoxin, denselben erzeugendes hybridoma und verfahren fuer die herstellung des gereinigten cytotoxin. - Google Patents

Monoklonaler antikoerper gegen ein cytotoxin, denselben erzeugendes hybridoma und verfahren fuer die herstellung des gereinigten cytotoxin.

Info

Publication number
DE3586536D1
DE3586536D1 DE8585115918T DE3586536T DE3586536D1 DE 3586536 D1 DE3586536 D1 DE 3586536D1 DE 8585115918 T DE8585115918 T DE 8585115918T DE 3586536 T DE3586536 T DE 3586536T DE 3586536 D1 DE3586536 D1 DE 3586536D1
Authority
DE
Germany
Prior art keywords
cytotoxin
production
monoclonal antibody
same
antibody against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585115918T
Other languages
English (en)
Other versions
DE122004000005I1 (de
DE3586536T2 (de
DE3586536T3 (de
Inventor
David Wallach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11055557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3586536(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of DE3586536D1 publication Critical patent/DE3586536D1/de
Publication of DE3586536T2 publication Critical patent/DE3586536T2/de
Application granted granted Critical
Publication of DE3586536T3 publication Critical patent/DE3586536T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3586536T 1984-12-20 1985-12-13 Monoklonaler Antikörper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren für die Herstellung des gereinigten Cytotoxin. Expired - Lifetime DE3586536T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL73883A IL73883A (en) 1984-12-20 1984-12-20 Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha

Publications (3)

Publication Number Publication Date
DE3586536D1 true DE3586536D1 (de) 1992-09-24
DE3586536T2 DE3586536T2 (de) 1993-02-18
DE3586536T3 DE3586536T3 (de) 2002-05-08

Family

ID=11055557

Family Applications (5)

Application Number Title Priority Date Filing Date
DE200412000017 Pending DE122004000017I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antik¦rper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren f}r die Herstellung des gereinigten Cytotoxin.
DE3586536T Expired - Lifetime DE3586536T3 (de) 1984-12-20 1985-12-13 Monoklonaler Antikörper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren für die Herstellung des gereinigten Cytotoxin.
DE198585115918T Pending DE186833T1 (de) 1984-12-20 1985-12-13 Zytotoxisches protein, verfahren zum isolieren desselben, monoklonaler antikoerper ct-1 und denselben erzeugendes hybridoma.
DE200412000007 Pending DE122004000007I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antikörper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren für die Herstellung des gereinigten Cytotoxin.
DE19853586536 Pending DE122004000005I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antik¦rper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren f}r die Herstellung des gereinigten Cytotoxin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200412000017 Pending DE122004000017I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antik¦rper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren f}r die Herstellung des gereinigten Cytotoxin.

Family Applications After (3)

Application Number Title Priority Date Filing Date
DE198585115918T Pending DE186833T1 (de) 1984-12-20 1985-12-13 Zytotoxisches protein, verfahren zum isolieren desselben, monoklonaler antikoerper ct-1 und denselben erzeugendes hybridoma.
DE200412000007 Pending DE122004000007I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antikörper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren für die Herstellung des gereinigten Cytotoxin.
DE19853586536 Pending DE122004000005I1 (de) 1984-12-20 1985-12-13 Monoklonaler Antik¦rper gegen ein Cytotoxin, denselben erzeugendes Hybridoma und Verfahren f}r die Herstellung des gereinigten Cytotoxin

Country Status (9)

Country Link
US (1) US6090923A (de)
EP (1) EP0186833B2 (de)
JP (2) JPS61191620A (de)
AU (1) AU601144B2 (de)
CA (1) CA1337518C (de)
DE (5) DE122004000017I1 (de)
IL (1) IL73883A (de)
NL (1) NL300142I2 (de)
ZA (1) ZA859757B (de)

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Also Published As

Publication number Publication date
ZA859757B (en) 1986-09-24
IL73883A0 (en) 1985-03-31
US6090923A (en) 2000-07-18
DE122004000017I1 (de) 2005-06-16
NL300142I1 (nl) 2004-04-01
AU601144B2 (en) 1990-09-06
NL300142I2 (nl) 2005-08-01
IL73883A (en) 1990-12-23
DE122004000005I1 (de) 2006-06-08
DE3586536T2 (de) 1993-02-18
EP0186833A2 (de) 1986-07-09
DE122004000007I1 (de) 2004-07-01
JPS61191620A (ja) 1986-08-26
EP0186833B1 (de) 1992-08-19
JPH0787966A (ja) 1995-04-04
AU5142485A (en) 1986-06-26
CA1337518C (en) 1995-11-07
DE3586536T3 (de) 2002-05-08
EP0186833B2 (de) 2001-11-28
DE186833T1 (de) 1986-12-18
EP0186833A3 (en) 1987-05-27

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