DE3586420T2 - Verwendung von dihydropyridinen zur behandlung und praevention von arteriosklerose. - Google Patents

Verwendung von dihydropyridinen zur behandlung und praevention von arteriosklerose.

Info

Publication number
DE3586420T2
DE3586420T2 DE8585115605T DE3586420T DE3586420T2 DE 3586420 T2 DE3586420 T2 DE 3586420T2 DE 8585115605 T DE8585115605 T DE 8585115605T DE 3586420 T DE3586420 T DE 3586420T DE 3586420 T2 DE3586420 T2 DE 3586420T2
Authority
DE
Germany
Prior art keywords
dihydropyridine
arteriosclerosis
nitrophenyl
treatment
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585115605T
Other languages
German (de)
English (en)
Other versions
DE3586420D1 (de
Inventor
Jiro Hirosumi
Isamu Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE3586420D1 publication Critical patent/DE3586420D1/de
Application granted granted Critical
Publication of DE3586420T2 publication Critical patent/DE3586420T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585115605T 1984-12-10 1985-12-07 Verwendung von dihydropyridinen zur behandlung und praevention von arteriosklerose. Expired - Fee Related DE3586420T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848431119A GB8431119D0 (en) 1984-12-10 1984-12-10 Anti-arteriosclerotic composition

Publications (2)

Publication Number Publication Date
DE3586420D1 DE3586420D1 (de) 1992-09-03
DE3586420T2 true DE3586420T2 (de) 1993-01-07

Family

ID=10570949

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585115605T Expired - Fee Related DE3586420T2 (de) 1984-12-10 1985-12-07 Verwendung von dihydropyridinen zur behandlung und praevention von arteriosklerose.

Country Status (5)

Country Link
US (1) US4859688A (enExample)
EP (1) EP0185283B1 (enExample)
JP (1) JPS61155327A (enExample)
DE (1) DE3586420T2 (enExample)
GB (1) GB8431119D0 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782070A (en) * 1986-07-01 1988-11-01 Fujisawa Pharmaceutical Co., Ltd. Cerebral dysfunction therapeutic agent, which comprises a dihydropyridine compound
US5045553A (en) * 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
DE69016014T2 (de) * 1990-07-04 1995-08-31 Marcin Krotkiewski Blutdrucksenkendes Präparat.
IT1244728B (it) * 1991-02-13 1994-08-08 Glaxo Spa Impiego medicamentoso di derivati diidropiridinici
WO2004110354A2 (en) * 2003-05-15 2004-12-23 Roskamp Research, Llc Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
CN101883564B (zh) * 2007-10-05 2013-10-16 阿尔茨海默病学会美国公司 使用(-)-尼伐地平对映体减少淀粉状蛋白沉积、淀粉状蛋白神经毒性和小神经胶质增生的方法
US20100093810A1 (en) * 2007-10-05 2010-04-15 Alzheimer's Institute Of America, Inc. Pharmaceutical Compositions for Reducing Amyloid Deposition, Amyloid Neurotoxicity, and Microgliosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338322A (en) * 1975-07-02 1982-07-06 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same
US4150119A (en) * 1976-10-22 1979-04-17 Jesus Emilio Lince Isaza Method for treatment of vascular disease
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
US4442100A (en) * 1979-12-11 1984-04-10 Bayer Aktiengesellschaft Substituted 2-amino-3,4-dihydropyridine derivatives, their production and their medicinal use
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
EP0125803A3 (en) * 1983-04-27 1987-01-21 FISONS plc Pharmaceutically active dihydropyridines

Also Published As

Publication number Publication date
EP0185283B1 (en) 1992-07-29
EP0185283A3 (en) 1989-07-19
EP0185283A2 (en) 1986-06-25
JPS61155327A (ja) 1986-07-15
DE3586420D1 (de) 1992-09-03
US4859688A (en) 1989-08-22
JPH0529209B2 (enExample) 1993-04-28
GB8431119D0 (en) 1985-01-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee