DE3566670D1 - Process and intermediates for sorbinil - Google Patents

Process and intermediates for sorbinil

Info

Publication number
DE3566670D1
DE3566670D1 DE8585305838T DE3566670T DE3566670D1 DE 3566670 D1 DE3566670 D1 DE 3566670D1 DE 8585305838 T DE8585305838 T DE 8585305838T DE 3566670 T DE3566670 T DE 3566670T DE 3566670 D1 DE3566670 D1 DE 3566670D1
Authority
DE
Germany
Prior art keywords
sorbinil
intermediates
processes
formulawherein
benzyloxycarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585305838T
Other languages
German (de)
English (en)
Inventor
Berkeley Wendell Cue
Bernard Shields Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3566670D1 publication Critical patent/DE3566670D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Peptides Or Proteins (AREA)
DE8585305838T 1984-08-23 1985-08-16 Process and intermediates for sorbinil Expired DE3566670D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/643,895 US4620019A (en) 1984-08-23 1984-08-23 S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil

Publications (1)

Publication Number Publication Date
DE3566670D1 true DE3566670D1 (en) 1989-01-12

Family

ID=24582609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585305838T Expired DE3566670D1 (en) 1984-08-23 1985-08-16 Process and intermediates for sorbinil

Country Status (25)

Country Link
US (2) US4620019A (enExample)
EP (1) EP0173522B1 (enExample)
JP (1) JPS6157575A (enExample)
KR (1) KR870000273B1 (enExample)
CN (1) CN1004074B (enExample)
AT (1) ATE39117T1 (enExample)
AU (1) AU553838B2 (enExample)
CA (1) CA1245667A (enExample)
DD (1) DD240204A5 (enExample)
DE (1) DE3566670D1 (enExample)
DK (1) DK380785A (enExample)
ES (3) ES8700260A1 (enExample)
FI (1) FI853182A7 (enExample)
GR (1) GR852007B (enExample)
HU (1) HU195660B (enExample)
IL (1) IL76150A (enExample)
IN (1) IN165762B (enExample)
NO (1) NO853305L (enExample)
NZ (1) NZ213196A (enExample)
PH (1) PH22577A (enExample)
PL (1) PL255117A1 (enExample)
PT (1) PT80996B (enExample)
SU (1) SU1380613A3 (enExample)
YU (1) YU43881B (enExample)
ZA (1) ZA856371B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5072006A (en) * 1988-12-09 1991-12-10 Recherche Syntex France S.A. Novel benzopyranylpyrrolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4348526A (en) * 1980-03-28 1982-09-07 Pfizer Inc. Intermediates in the preparation of chiral hydantoins
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
DE3367103D1 (en) * 1982-11-10 1986-11-27 Pfizer Sorbinil by optical resolution with aminopinane derivatives
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4431828A (en) * 1982-11-10 1984-02-14 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil

Also Published As

Publication number Publication date
FI853182L (fi) 1986-02-24
DK380785A (da) 1986-02-24
CN1004074B (zh) 1989-05-03
DD240204A5 (de) 1986-10-22
FI853182A7 (fi) 1986-02-24
US4620019A (en) 1986-10-28
ATE39117T1 (de) 1988-12-15
ES551962A0 (es) 1987-06-01
FI853182A0 (fi) 1985-08-19
AU553838B2 (en) 1986-07-31
ES8706142A1 (es) 1987-06-01
HUT44556A (en) 1988-03-28
HU195660B (en) 1988-06-28
PL255117A1 (en) 1986-12-30
CN85104685A (zh) 1986-12-24
EP0173522A3 (en) 1986-12-30
NO853305L (no) 1986-02-24
AU4654785A (en) 1986-02-27
JPS6157575A (ja) 1986-03-24
YU133185A (en) 1988-04-30
ES8700260A1 (es) 1986-10-16
IN165762B (enExample) 1990-01-06
ES551961A0 (es) 1987-06-01
ES8706141A1 (es) 1987-06-01
ZA856371B (en) 1987-04-29
YU43881B (en) 1989-12-31
EP0173522B1 (en) 1988-12-07
PT80996B (pt) 1987-12-30
DK380785D0 (da) 1985-08-22
NZ213196A (en) 1988-04-29
ES546343A0 (es) 1986-10-16
GR852007B (enExample) 1985-12-19
PT80996A (en) 1985-09-01
CA1245667A (en) 1988-11-29
SU1380613A3 (ru) 1988-03-07
PH22577A (en) 1988-10-17
IL76150A (en) 1989-03-31
KR870000273B1 (ko) 1987-02-23
US4704461A (en) 1987-11-03
EP0173522A2 (en) 1986-03-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee