ZA856371B - Process and intermediates for sorbinil - Google Patents

Process and intermediates for sorbinil

Info

Publication number
ZA856371B
ZA856371B ZA856371A ZA856371A ZA856371B ZA 856371 B ZA856371 B ZA 856371B ZA 856371 A ZA856371 A ZA 856371A ZA 856371 A ZA856371 A ZA 856371A ZA 856371 B ZA856371 B ZA 856371B
Authority
ZA
South Africa
Prior art keywords
sorbinil
intermediates
processes
formulawherein
benzyloxycarbonyl
Prior art date
Application number
ZA856371A
Inventor
Berkeley Wendell Cue Jr
Bernard Shields Moore
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA856371B publication Critical patent/ZA856371B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

Chiral sorbinil intermediates of the formulawherein R is hydrogen or benzyloxycarbonyl and Y is hydroxy or amino, processes therefor, and processes forthe conversion thereof to sorbinil.
ZA856371A 1984-08-23 1985-08-22 Process and intermediates for sorbinil ZA856371B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/643,895 US4620019A (en) 1984-08-23 1984-08-23 S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil

Publications (1)

Publication Number Publication Date
ZA856371B true ZA856371B (en) 1987-04-29

Family

ID=24582609

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856371A ZA856371B (en) 1984-08-23 1985-08-22 Process and intermediates for sorbinil

Country Status (25)

Country Link
US (2) US4620019A (en)
EP (1) EP0173522B1 (en)
JP (1) JPS6157575A (en)
KR (1) KR870000273B1 (en)
CN (1) CN1004074B (en)
AT (1) ATE39117T1 (en)
AU (1) AU553838B2 (en)
CA (1) CA1245667A (en)
DD (1) DD240204A5 (en)
DE (1) DE3566670D1 (en)
DK (1) DK380785A (en)
ES (3) ES8700260A1 (en)
FI (1) FI853182L (en)
GR (1) GR852007B (en)
HU (1) HU195660B (en)
IL (1) IL76150A (en)
IN (1) IN165762B (en)
NO (1) NO853305L (en)
NZ (1) NZ213196A (en)
PH (1) PH22577A (en)
PL (1) PL255117A1 (en)
PT (1) PT80996B (en)
SU (1) SU1380613A3 (en)
YU (1) YU43881B (en)
ZA (1) ZA856371B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5072006A (en) * 1988-12-09 1991-12-10 Recherche Syntex France S.A. Novel benzopyranylpyrrolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
US4348526A (en) * 1980-03-28 1982-09-07 Pfizer Inc. Intermediates in the preparation of chiral hydantoins
DE3367103D1 (en) * 1982-11-10 1986-11-27 Pfizer Sorbinil by optical resolution with aminopinane derivatives
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4431828A (en) * 1982-11-10 1984-02-14 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil

Also Published As

Publication number Publication date
AU553838B2 (en) 1986-07-31
PT80996A (en) 1985-09-01
PH22577A (en) 1988-10-17
PT80996B (en) 1987-12-30
NO853305L (en) 1986-02-24
FI853182L (en) 1986-02-24
AU4654785A (en) 1986-02-27
US4620019A (en) 1986-10-28
DE3566670D1 (en) 1989-01-12
ES8706142A1 (en) 1987-06-01
ES551961A0 (en) 1987-06-01
ES8706141A1 (en) 1987-06-01
NZ213196A (en) 1988-04-29
IL76150A (en) 1989-03-31
IN165762B (en) 1990-01-06
CA1245667A (en) 1988-11-29
DK380785A (en) 1986-02-24
HUT44556A (en) 1988-03-28
YU43881B (en) 1989-12-31
FI853182A0 (en) 1985-08-19
GR852007B (en) 1985-12-19
ES8700260A1 (en) 1986-10-16
EP0173522A2 (en) 1986-03-05
ATE39117T1 (en) 1988-12-15
CN85104685A (en) 1986-12-24
DK380785D0 (en) 1985-08-22
SU1380613A3 (en) 1988-03-07
JPS6157575A (en) 1986-03-24
PL255117A1 (en) 1986-12-30
ES551962A0 (en) 1987-06-01
CN1004074B (en) 1989-05-03
ES546343A0 (en) 1986-10-16
US4704461A (en) 1987-11-03
DD240204A5 (en) 1986-10-22
KR870000273B1 (en) 1987-02-23
EP0173522A3 (en) 1986-12-30
EP0173522B1 (en) 1988-12-07
YU133185A (en) 1988-04-30
HU195660B (en) 1988-06-28

Similar Documents

Publication Publication Date Title
IL75133A (en) Process for the preparation of 1,2-diacyl-s,n-glycerophosphocholines(or glycerophosphoethanolamines)and some novel intermediates therefor
ES8602940A1 (en) Process for the production of L-carnitine in a microbiological way.
DE3566670D1 (en) Process and intermediates for sorbinil
IL65597A (en) Preparation of 1alpha,24,25-trihydroxy-and 24,25-dihydroxy-cholesterol and certain novel intermediates used therein
PT79827A (en) Process for re-tannig of minerally tanned hides
ZA858604B (en) Process for improving the light-fastness of leather dyeings
SU1192263A1 (en) Method of manufacturing diamonds
ES8609301A1 (en) Process for the preparation of 3-methyl-7-fluoro-5-nitro- benzothiophene
SU1208765A1 (en) Method of obtaining phenolxyphenylcarbamide
SU1220344A1 (en) Device for fermentative treating of materials
SU1181318A1 (en) Method of thermal treating of steel
SU1220180A1 (en) Mass-exchange plant
SU1233456A1 (en) Method of obtaining substituted n-[(1,3,5-thiazine-2-il)aminocarbonyl]benzosulfonamids
SU1264575A1 (en) Method of cell immobilization
SU1182881A1 (en) Method of activation analysis
SU1216944A1 (en) Method of obtaining 2,6-di-tret-butylphenol
SU1240079A1 (en) Method of obtaining tetrabutoxititanium
SU1162200A1 (en) Method of obtaining mixture of methylchlorsilanes
SU1192351A1 (en) Method of cleaning wine making produce
SU1253113A1 (en) Method of obtaining cis-1,4-polybutadiene
SU1244928A1 (en) Method of obtaining cis-1,4-polybutadiene
SU1215222A1 (en) Method of producing carrier for methane conversion catalyzer
SU1220227A1 (en) Method of producing titanium-base porous blanks
SU1269465A1 (en) Method of obtaining 2-aniline-7-hydroxi-6h-1,3,4-thiadziazipyne of common formula
SU1154903A1 (en) Method of obtaining 2-imino-3-phenyl-6-phenacyliden-2,3,5,6-tetrahydro-1,3,4-oxadiazin-5-ones