DE3538747C2 - - Google Patents

Info

Publication number
DE3538747C2
DE3538747C2 DE3538747A DE3538747A DE3538747C2 DE 3538747 C2 DE3538747 C2 DE 3538747C2 DE 3538747 A DE3538747 A DE 3538747A DE 3538747 A DE3538747 A DE 3538747A DE 3538747 C2 DE3538747 C2 DE 3538747C2
Authority
DE
Germany
Prior art keywords
compound
general formula
formula
reaction
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3538747A
Other languages
German (de)
English (en)
Other versions
DE3538747A1 (de
Inventor
Don Ki Seoul Kr Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BORYUNG PHARMACEUTICAL Co Ltd SEOUL KR
Original Assignee
BORYUNG PHARMACEUTICAL Co Ltd SEOUL KR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BORYUNG PHARMACEUTICAL Co Ltd SEOUL KR filed Critical BORYUNG PHARMACEUTICAL Co Ltd SEOUL KR
Publication of DE3538747A1 publication Critical patent/DE3538747A1/de
Application granted granted Critical
Publication of DE3538747C2 publication Critical patent/DE3538747C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE19853538747 1985-02-11 1985-10-31 Verfahren zur herstellung von pyrrolidin-derivaten Granted DE3538747A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019850000850A KR870001569B1 (ko) 1985-02-11 1985-02-11 피롤리딘 유도체의 제조방법

Publications (2)

Publication Number Publication Date
DE3538747A1 DE3538747A1 (de) 1986-08-14
DE3538747C2 true DE3538747C2 (ro) 1988-08-18

Family

ID=19239706

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853538747 Granted DE3538747A1 (de) 1985-02-11 1985-10-31 Verfahren zur herstellung von pyrrolidin-derivaten

Country Status (6)

Country Link
JP (1) JPS61183263A (ro)
KR (1) KR870001569B1 (ro)
DE (1) DE3538747A1 (ro)
ES (1) ES8606269A1 (ro)
FR (1) FR2577222B1 (ro)
GB (1) GB2170806B (ro)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208954B (en) * 1990-09-21 1994-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
JPH04503662A (ja) * 1988-08-26 1992-07-02 セプラコア，インコーポレーテッド カプトプリルおよびその類縁体の誘導体並びに前駆体
US5237073A (en) * 1988-08-26 1993-08-17 Sepracor, Inc. Derivatives and precursors of captopril and its analogues
KR940005014B1 (ko) * 1991-11-07 1994-06-09 보령제약 주식회사 피롤리딘카르복실산 유도체의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4192945A (en) * 1978-12-07 1980-03-11 E. R. Squibb & Sons, Inc. Process for preparing proline and homoproline derivatives
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
JPS58124764A (ja) * 1982-01-20 1983-07-25 Kanegafuchi Chem Ind Co Ltd 光学活性チオ−ル化合物の製造法

Also Published As

Publication number Publication date
ES548744A0 (es) 1986-04-01
ES8606269A1 (es) 1986-04-01
KR860006441A (ko) 1986-09-11
DE3538747A1 (de) 1986-08-14
KR870001569B1 (ko) 1987-09-04
GB2170806A (en) 1986-08-13
GB8602782D0 (en) 1986-03-12
FR2577222B1 (fr) 1987-12-24
JPS61183263A (ja) 1986-08-15
GB2170806B (en) 1988-08-03
FR2577222A1 (fr) 1986-08-14

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8363 Opposition against the patent
8328 Change in the person/name/address of the agent

Free format text: ZELLENTIN, R., DIPL.-GEOLOGE DR.RER.NAT., 8000 MUENCHEN ZELLENTIN, W., DIPL.-ING. GRUSSDORF, J., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 6700 LUDWIGSHAFEN

8331 Complete revocation