DE3485001D1 - Reinigung und charakterisierung eines fibroblastwachstumsfaktors. - Google Patents

Reinigung und charakterisierung eines fibroblastwachstumsfaktors.

Info

Publication number
DE3485001D1
DE3485001D1 DE8484106375T DE3485001T DE3485001D1 DE 3485001 D1 DE3485001 D1 DE 3485001D1 DE 8484106375 T DE8484106375 T DE 8484106375T DE 3485001 T DE3485001 T DE 3485001T DE 3485001 D1 DE3485001 D1 DE 3485001D1
Authority
DE
Germany
Prior art keywords
characterization
cleaning
growth factor
fibroblast growth
fibroblast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484106375T
Other languages
German (de)
English (en)
Inventor
Thomas, Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3485001D1 publication Critical patent/DE3485001D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/839—Nerves; brain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8484106375T 1983-06-17 1984-06-05 Reinigung und charakterisierung eines fibroblastwachstumsfaktors. Expired - Lifetime DE3485001D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/505,553 US4444760A (en) 1983-06-17 1983-06-17 Purification and characterization of a protein fibroblast growth factor

Publications (1)

Publication Number Publication Date
DE3485001D1 true DE3485001D1 (de) 1991-10-10

Family

ID=24010776

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484106375T Expired - Lifetime DE3485001D1 (de) 1983-06-17 1984-06-05 Reinigung und charakterisierung eines fibroblastwachstumsfaktors.

Country Status (7)

Country Link
US (1) US4444760A (enExample)
EP (1) EP0131150B1 (enExample)
JP (1) JPS6011424A (enExample)
CA (1) CA1241639A (enExample)
CY (1) CY1780A (enExample)
DE (1) DE3485001D1 (enExample)
HK (1) HK42694A (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5885899A (ja) * 1981-11-16 1983-05-23 Fujirebio Inc アミラ−ゼインヒビタ−およびその製造法
JPS6028999A (ja) * 1983-06-30 1985-02-14 Maruho Kk 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法
US5464774A (en) * 1984-03-05 1995-11-07 The Salk Institute For Biological Studies Bovine basic fibroblast growth factor
US4785079A (en) * 1984-11-09 1988-11-15 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
AU596954B2 (en) * 1984-11-29 1990-05-24 Curatech, Inc. Wound healing agents
DE3584005D1 (de) * 1984-12-24 1991-10-10 Merck & Co Inc Im gehirn entstehender wachstumsfaktor.
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
US5859208A (en) * 1988-07-06 1999-01-12 Fiddes; John C. Human basic fibroblast growth factor analog
US5439818A (en) * 1985-09-12 1995-08-08 Scios Nova Inc. DNA encoding human recombinant basic fibroblast growth factor
DE3650774T2 (de) * 1985-09-12 2003-05-28 Scios Inc., Sunnyvale Rekombinante Fibroblasten-Wachstums-Faktoren
US5827826A (en) 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
US5552528A (en) * 1986-03-03 1996-09-03 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bovine b-endothelial cell growth factor
EP0246753B1 (en) * 1986-04-22 1994-07-13 The Salk Institute For Biological Studies Fibroblast growth factor antagonists
CA1294546C (en) * 1986-04-23 1992-01-21 John S. Sundsmo Wound healing composition containing collagen
NZ220917A (en) * 1986-07-11 1991-05-28 Merck & Co Inc Human and bovine acidic fibroblast growth factor vectors, hosts and compositions
US4902782A (en) * 1986-12-10 1990-02-20 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
FR2613936B1 (fr) * 1987-04-17 1990-03-30 Centre Nat Rech Scient Application des resines constituees par des polymeres fonctionnels comme phase stationnaire en chromatographie d'affinite pour la purification des facteurs de croissance et procede de purification correspondant
US5459250A (en) 1987-06-16 1995-10-17 New York University Truncated mammalian growth factor DNA sequence
US5750659A (en) * 1987-06-16 1998-05-12 New York University Mammalian growth factor
WO1988010269A1 (en) * 1987-06-18 1988-12-29 Monash University Growth factors
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US5312911A (en) * 1987-10-22 1994-05-17 Merck & Co., Inc. Cysteine-modified acidic fibroblast growth factor
EP0422104A4 (en) * 1988-06-22 1991-11-21 Synergen, Inc. Angiogenic potentiating peptides which potentiate angiogenic factors
EP0396719B1 (en) * 1988-11-04 1995-07-05 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5250414A (en) * 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
DE3900198A1 (de) * 1989-01-05 1990-07-12 Merck Patent Gmbh Topisch anwendbare pharmazeutische zubereitung
ES2153816T3 (es) 1989-01-31 2001-03-16 Jeffrey S Rubin Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
US7026291B1 (en) 1989-01-31 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
US20030114374A1 (en) * 1989-05-12 2003-06-19 Genentech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
US5332671A (en) * 1989-05-12 1994-07-26 Genetech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
US7300791B2 (en) * 1989-05-12 2007-11-27 Genentech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
CA2020720A1 (en) * 1989-07-13 1991-01-14 Shigeko Yamazaki Method for the purification of therapeutically active recombinant acidic fibroblast growth factor
US5043431A (en) * 1989-09-11 1991-08-27 Codon Method and apparatus for the production of TGF-β
US5169837A (en) * 1991-03-28 1992-12-08 Allelix Biopharmaceuticals Inc. Isolated osteogenic factor
US5591709A (en) * 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
JPH08501203A (ja) * 1992-06-03 1996-02-13 ケイス・ウエスタン・リザーブ・ユニバーシティー 生理活性物質を連続的に適用するための包帯
US5331095A (en) * 1993-04-12 1994-07-19 Scios Nova Inc. Process for purification of basic fibroblast growth factor
US5800808A (en) * 1994-05-24 1998-09-01 Veda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
US5733884A (en) * 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
CN100341895C (zh) * 1998-10-08 2007-10-10 张建军 哺乳动物心肌中提取酸性成纤维细胞生长因子样物质的方法
US6897061B1 (en) * 2000-06-16 2005-05-24 Spinal Cord Society Transdifferentiation of glial cells
US7306919B1 (en) 2001-10-31 2007-12-11 Thornthwaite Jerry T Antigen-antibody cancer recognition system
KR20040081749A (ko) * 2002-01-14 2004-09-22 헨리 포드 헬쓰 시스템 혈관을 형성하고 혈관신생 및 영양 인자를 생성시키는데사용하기 위한 골수 기질 세포로부터의 물질
WO2006102488A1 (en) * 2005-03-22 2006-09-28 Cascade Medical Enterprises, Llc Systems and methods of producing membranes
US8350013B2 (en) * 2006-09-08 2013-01-08 Wyeth Llc Arginine wash in protein purification using affinity chromatography
KR101021197B1 (ko) 2008-04-11 2011-03-11 (주)케어젠 성장인자―미미킹 펩타이드 및 그의 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195017A (en) * 1975-02-25 1980-03-25 Samuel Bogoch Malignin, derived from brain tumor cells, complexes and polypeptides thereof

Also Published As

Publication number Publication date
US4444760A (en) 1984-04-24
CA1241639A (en) 1988-09-06
EP0131150B1 (en) 1991-09-04
JPH0430960B2 (enExample) 1992-05-25
HK42694A (en) 1994-05-13
CY1780A (en) 1995-10-20
JPS6011424A (ja) 1985-01-21
EP0131150A3 (en) 1987-07-15
EP0131150A2 (en) 1985-01-16

Similar Documents

Publication Publication Date Title
DE3485001D1 (de) Reinigung und charakterisierung eines fibroblastwachstumsfaktors.
DE3775179D1 (de) Reinigungsverfahren und glaenzend machendes aufgespruehtes reinigungsmittel.
DE69024261D1 (de) Reinigung und Charakterisierung eines von einem Glioma abstammenden Wachstumsfaktors
IT8921642A0 (it) Procedimento ed apparecchiatura per la pulizia.
FI98762B (fi) Säiliön viimeistelyn tarkastus
FR2545352B1 (fr) Prothese d'epaule
FR2547197B1 (fr) Composition de nettoyage et d'essuyage de la region circumanale
DK424289A (da) Vandigt rengoerings- og efterbehandlingsmiddel
GB9013410D0 (en) Polypeptide and its use
EP0450598A3 (en) Inhibitors of the advanced glycosylation of proteins and methods of use therefor
NO173921C (no) Fremgangsmaate til rengjoering av en gjenstands overflate
FI101418B1 (fi) Kerrosastian kehysrakenne
FI893293A0 (fi) Foerfaranden foer framstaellning av morniflumat och analoga foereningar.
AU3681784A (en) Cleaning and painting structures
IL72467A0 (en) New 1,2-diaryl-3-azolylpropane derivatives,their preparation and their use as agents for the treatment of plants
FR2650957B1 (fr) Embase amovible de catheter et methode de mise en place de l'embase sur un catheter
FI923419A7 (fi) Menetelmä ja laitos elintarvikevalmisteiden säilyvyyden parantamiseksi
ZA845618B (en) New 1,2-diaryl-3-azolylpropane derivatives,their preparation and their use as agents for the treatment of plants
NO870739D0 (no) Renset human angiogen faktor og fremgangsmaate for dens fremstilling.
DE69121210D1 (de) Therapeutische verwendung des fibroblastenwachstumsfaktors
EP0426573A3 (en) Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same
KR880002226U (ko) 도장겸용 필기구
KR870018233U (ko) 상하 이동식 칠판
KR890020765U (ko) 표면세척부 여과기
ES1007957Y (es) Limpiador manual de alturas y rinconeras.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition