DE3432143A1 - Verfahren zur einkapselung eines einzuhuellenden materials - Google Patents

Verfahren zur einkapselung eines einzuhuellenden materials

Info

Publication number
DE3432143A1
DE3432143A1 DE19843432143 DE3432143A DE3432143A1 DE 3432143 A1 DE3432143 A1 DE 3432143A1 DE 19843432143 DE19843432143 DE 19843432143 DE 3432143 A DE3432143 A DE 3432143A DE 3432143 A1 DE3432143 A1 DE 3432143A1
Authority
DE
Germany
Prior art keywords
polymer
capsule
cells
solution
anions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19843432143
Other languages
German (de)
English (en)
Other versions
DE3432143C2 (US07943777-20110517-C00090.png
Inventor
Allan P. Newburyport Mass. Jarvis jun.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of DE3432143A1 publication Critical patent/DE3432143A1/de
Application granted granted Critical
Publication of DE3432143C2 publication Critical patent/DE3432143C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE19843432143 1983-09-01 1984-08-31 Verfahren zur einkapselung eines einzuhuellenden materials Granted DE3432143A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52839583A 1983-09-01 1983-09-01

Publications (2)

Publication Number Publication Date
DE3432143A1 true DE3432143A1 (de) 1985-03-21
DE3432143C2 DE3432143C2 (US07943777-20110517-C00090.png) 1987-05-14

Family

ID=24105521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843432143 Granted DE3432143A1 (de) 1983-09-01 1984-08-31 Verfahren zur einkapselung eines einzuhuellenden materials

Country Status (14)

Country Link
JP (1) JPS6075326A (US07943777-20110517-C00090.png)
AU (1) AU563653B2 (US07943777-20110517-C00090.png)
BE (1) BE900469A (US07943777-20110517-C00090.png)
CA (1) CA1245984A (US07943777-20110517-C00090.png)
CH (1) CH664472A5 (US07943777-20110517-C00090.png)
DE (1) DE3432143A1 (US07943777-20110517-C00090.png)
DK (1) DK419184A (US07943777-20110517-C00090.png)
FR (1) FR2551455B1 (US07943777-20110517-C00090.png)
GB (1) GB2145992B (US07943777-20110517-C00090.png)
IL (1) IL72787A (US07943777-20110517-C00090.png)
IT (1) IT1196742B (US07943777-20110517-C00090.png)
NL (1) NL8402671A (US07943777-20110517-C00090.png)
NO (1) NO843481L (US07943777-20110517-C00090.png)
SE (1) SE8404343L (US07943777-20110517-C00090.png)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590071C2 (de) * 1984-02-23 1988-05-05 Snow Brand Milk Products Co Ltd Verfahren zur Herstellung von Kapseln
DE3941873A1 (de) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen
DE4012079A1 (de) * 1990-04-14 1991-10-24 Jakob Dr Bodziony Implantable semipermeable austausch- und diffusionskammer

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO166836C (no) * 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
GB8705464D0 (en) * 1987-03-09 1987-04-15 Atomic Energy Authority Uk Composite material
JPS6434436A (en) * 1987-07-28 1989-02-03 Sanyo Chemical Ind Ltd Gel cellular beads and manufacture thereof
CA1319632C (en) * 1988-04-22 1993-06-29 Carol Louise Nolan Method for microbial immobilization
US4952618A (en) * 1988-05-03 1990-08-28 Minnesota Mining And Manufacturing Company Hydrocolloid/adhesive composition
US5562099A (en) * 1990-10-05 1996-10-08 Massachusetts Institute Of Technology Polymeric microparticles containing agents for imaging
US5487390A (en) * 1990-10-05 1996-01-30 Massachusetts Institute Of Technology Gas-filled polymeric microbubbles for ultrasound imaging
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
FR2694894B1 (fr) * 1992-08-20 1994-11-10 Coletica Utilisation d'une réaction de transacylation entre un polysaccharide estérifié et une substance polyaminée ou polyhydroxylée pour la fabrication de microparticules, procédé et composition.
FR2703927B1 (fr) * 1993-04-13 1995-07-13 Coletica Utilisation d'une réaction de transacylation entre un polysaccharide estérifié et une polyamine pour former en milieu aqueux une membrane au moins en surface de particules gélifiées.
DE4312970A1 (de) * 1993-04-21 1994-10-27 Juergen Dr Schrezenmeir Mikrokapsel sowie Verfahren und Vorrichtung zu ihrer Herstellung
DE4426396A1 (de) * 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Verfahren zur Herstellung konzentrierter Lösungen von mikroverkapselten Zellen oder von suspendierten Wirkstoffen in mikroverkapselter Form
US5540927A (en) * 1995-04-12 1996-07-30 Monsanto Company Microencapsulation process by coacervation
EP1647270B1 (de) * 1998-03-19 2009-06-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Aufbringen mehrerer Schichten von Beschichtungssubstanzen auf Templatpartikel
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
DE102004013637A1 (de) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
DE102005002483A1 (de) * 2005-01-18 2006-08-03 Ehrfeld Mikrotechnik Bts Gmbh Verfahren zum Einkapseln von Sensormolekülen mit einer semipermeablen Membran
FR2986165B1 (fr) 2012-01-31 2015-07-24 Capsum Procede de preparation de capsules rigidifiees

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209045A1 (de) * 1981-03-13 1982-09-30 Damon Corp., 02194 Needham Heights, Mass. Verfahren zum selektiven aufbrechen permeabler membranen
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
DE3209045A1 (de) * 1981-03-13 1982-09-30 Damon Corp., 02194 Needham Heights, Mass. Verfahren zum selektiven aufbrechen permeabler membranen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590071C2 (de) * 1984-02-23 1988-05-05 Snow Brand Milk Products Co Ltd Verfahren zur Herstellung von Kapseln
DE3941873A1 (de) * 1989-12-19 1991-06-20 Jakob Dr Bodziony Hohlfaser mit der beschichtung von zellen, die mehrjaehrige implantation in arterien und venen ermoeglichen
DE4012079A1 (de) * 1990-04-14 1991-10-24 Jakob Dr Bodziony Implantable semipermeable austausch- und diffusionskammer
DE4012079C2 (de) * 1990-04-14 1997-11-06 Jakob Dr Bodziony Implantierbare Austausch- und Diffusionskammer

Also Published As

Publication number Publication date
FR2551455A1 (fr) 1985-03-08
IT8467874A0 (it) 1984-09-03
DK419184D0 (da) 1984-08-31
IT8467874A1 (it) 1986-03-03
DK419184A (da) 1985-03-02
JPS6075326A (ja) 1985-04-27
NO843481L (no) 1985-03-04
GB2145992A (en) 1985-04-11
SE8404343D0 (sv) 1984-08-31
GB8422052D0 (en) 1984-10-03
IL72787A (en) 1987-12-31
CA1245984A (en) 1988-12-06
FR2551455B1 (fr) 1989-09-15
DE3432143C2 (US07943777-20110517-C00090.png) 1987-05-14
AU3263484A (en) 1985-03-07
AU563653B2 (en) 1987-07-16
SE8404343L (sv) 1985-03-02
GB2145992B (en) 1987-02-18
IT1196742B (it) 1988-11-25
BE900469A (fr) 1984-12-17
IL72787A0 (en) 1984-11-30
CH664472A5 (de) 1988-03-15
NL8402671A (nl) 1985-04-01

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee