DE3408196A1 - Carbapenem-zwischenverbindungen, verfahren zu deren herstellung und zu deren weiterverarbeitung - Google Patents

Carbapenem-zwischenverbindungen, verfahren zu deren herstellung und zu deren weiterverarbeitung

Info

Publication number
DE3408196A1
DE3408196A1 DE19843408196 DE3408196A DE3408196A1 DE 3408196 A1 DE3408196 A1 DE 3408196A1 DE 19843408196 DE19843408196 DE 19843408196 DE 3408196 A DE3408196 A DE 3408196A DE 3408196 A1 DE3408196 A1 DE 3408196A1
Authority
DE
Germany
Prior art keywords
general formula
compound
group
iii
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19843408196
Other languages
German (de)
English (en)
Other versions
DE3408196C2 (nl
Inventor
Guy St. Lambert Roberge
Yasutsugu Quebec Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE3408196A1 publication Critical patent/DE3408196A1/de
Application granted granted Critical
Publication of DE3408196C2 publication Critical patent/DE3408196C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C245/18—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19843408196 1983-03-07 1984-03-06 Carbapenem-zwischenverbindungen, verfahren zu deren herstellung und zu deren weiterverarbeitung Granted DE3408196A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47244383A 1983-03-07 1983-03-07

Publications (2)

Publication Number Publication Date
DE3408196A1 true DE3408196A1 (de) 1984-09-13
DE3408196C2 DE3408196C2 (nl) 1992-03-19

Family

ID=23875532

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843408196 Granted DE3408196A1 (de) 1983-03-07 1984-03-06 Carbapenem-zwischenverbindungen, verfahren zu deren herstellung und zu deren weiterverarbeitung

Country Status (10)

Country Link
JP (3) JPS59170096A (nl)
BE (1) BE899085A (nl)
CA (1) CA1220215A (nl)
CY (1) CY1447A (nl)
DE (1) DE3408196A1 (nl)
FR (1) FR2542317B1 (nl)
GB (1) GB2136009B (nl)
HK (1) HK84588A (nl)
IT (1) IT1175944B (nl)
MY (1) MY8800117A (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3613366A1 (de) * 1985-04-22 1986-11-20 Bristol-Myers Co., New York, N.Y. Carbapenem-zwischenverbindungen und verfahren zu deren herstellung

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340927A (en) * 1989-07-18 1994-08-23 Merck & Co., Inc. Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174316A (en) * 1978-08-14 1979-11-13 Merck & Co., Inc. 4-Iodomethylazetidin-2-one
US4290947A (en) * 1979-04-27 1981-09-22 Merck & Co., Inc. Process for the preparation of thienamycin and intermediates
PT71553B (en) * 1979-07-23 1981-12-14 Merck & Co Inc Process for the preparation of thienamycin and intermediates
US4360684A (en) * 1981-04-08 1982-11-23 Merck & Co., Inc. Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid
JPS58103358A (ja) * 1981-10-23 1983-06-20 メルク・エンド・カムパニ−・インコ−ポレ−テツド 抗生物質中間体の製造方法
CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JA CS, 103 (20) 1981, S. 6765-6767 *
Tet. Letters 23 (22) 1982, S. 2293-2296 *
Tet. Letters 23 (4) 1982, S. 379-382 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3613366A1 (de) * 1985-04-22 1986-11-20 Bristol-Myers Co., New York, N.Y. Carbapenem-zwischenverbindungen und verfahren zu deren herstellung

Also Published As

Publication number Publication date
FR2542317A1 (fr) 1984-09-14
CA1220215A (en) 1987-04-07
IT1175944B (it) 1987-08-12
BE899085A (fr) 1984-09-06
DE3408196C2 (nl) 1992-03-19
JPH0564157B2 (nl) 1993-09-14
JPH09176113A (ja) 1997-07-08
GB8405878D0 (en) 1984-04-11
JPS59170096A (ja) 1984-09-26
GB2136009A (en) 1984-09-12
JPH0827168A (ja) 1996-01-30
HK84588A (en) 1988-10-28
CY1447A (en) 1989-03-10
MY8800117A (en) 1988-12-31
GB2136009B (en) 1986-04-30
IT8419891A0 (it) 1984-03-02
FR2542317B1 (fr) 1987-11-27

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: BRISTOL-MYERS SQUIBB CO. (N.D.GES.D.STAATES DELAWA

8128 New person/name/address of the agent

Representative=s name: KINZEBACH, W., DIPL.-CHEM. DR.PHIL. RIEDL, P., DIP

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee