GB2136009B - Carbapenem intermediates - Google Patents

Carbapenem intermediates

Info

Publication number
GB2136009B
GB2136009B GB08405878A GB8405878A GB2136009B GB 2136009 B GB2136009 B GB 2136009B GB 08405878 A GB08405878 A GB 08405878A GB 8405878 A GB8405878 A GB 8405878A GB 2136009 B GB2136009 B GB 2136009B
Authority
GB
United Kingdom
Prior art keywords
carbapenem intermediates
carbapenem
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08405878A
Other versions
GB8405878D0 (en
GB2136009A (en
Inventor
Yasatsugu Ueda
Guy Roberge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB8405878D0 publication Critical patent/GB8405878D0/en
Publication of GB2136009A publication Critical patent/GB2136009A/en
Application granted granted Critical
Publication of GB2136009B publication Critical patent/GB2136009B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C245/18—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
GB08405878A 1983-03-07 1984-03-06 Carbapenem intermediates Expired GB2136009B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47244383A 1983-03-07 1983-03-07

Publications (3)

Publication Number Publication Date
GB8405878D0 GB8405878D0 (en) 1984-04-11
GB2136009A GB2136009A (en) 1984-09-12
GB2136009B true GB2136009B (en) 1986-04-30

Family

ID=23875532

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08405878A Expired GB2136009B (en) 1983-03-07 1984-03-06 Carbapenem intermediates

Country Status (10)

Country Link
JP (3) JPS59170096A (en)
BE (1) BE899085A (en)
CA (1) CA1220215A (en)
CY (1) CY1447A (en)
DE (1) DE3408196A1 (en)
FR (1) FR2542317B1 (en)
GB (1) GB2136009B (en)
HK (1) HK84588A (en)
IT (1) IT1175944B (en)
MY (1) MY8800117A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683296A (en) * 1983-03-07 1987-07-28 Bristol-Myers Company Carbapenem intermediates
US5340927A (en) * 1989-07-18 1994-08-23 Merck & Co., Inc. Process for the preparation of 2-diazo-3-trisubstituted silyloxy 3-butenoates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4174316A (en) * 1978-08-14 1979-11-13 Merck & Co., Inc. 4-Iodomethylazetidin-2-one
US4290947A (en) * 1979-04-27 1981-09-22 Merck & Co., Inc. Process for the preparation of thienamycin and intermediates
PT71553B (en) * 1979-07-23 1981-12-14 Merck & Co Inc Process for the preparation of thienamycin and intermediates
US4360684A (en) * 1981-04-08 1982-11-23 Merck & Co., Inc. Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid
CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis
JPS58103358A (en) * 1981-10-23 1983-06-20 メルク・エンド・カムパニ−・インコ−ポレ−テツド Synthesization of antibiotic

Also Published As

Publication number Publication date
GB8405878D0 (en) 1984-04-11
DE3408196A1 (en) 1984-09-13
BE899085A (en) 1984-09-06
CY1447A (en) 1989-03-10
FR2542317B1 (en) 1987-11-27
HK84588A (en) 1988-10-28
FR2542317A1 (en) 1984-09-14
IT8419891A0 (en) 1984-03-02
JPH0827168A (en) 1996-01-30
JPH0564157B2 (en) 1993-09-14
GB2136009A (en) 1984-09-12
IT1175944B (en) 1987-08-12
CA1220215A (en) 1987-04-07
DE3408196C2 (en) 1992-03-19
JPS59170096A (en) 1984-09-26
MY8800117A (en) 1988-12-31
JPH09176113A (en) 1997-07-08

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19980306