DE3404470C2 - - Google Patents

Info

Publication number
DE3404470C2
DE3404470C2 DE3404470A DE3404470A DE3404470C2 DE 3404470 C2 DE3404470 C2 DE 3404470C2 DE 3404470 A DE3404470 A DE 3404470A DE 3404470 A DE3404470 A DE 3404470A DE 3404470 C2 DE3404470 C2 DE 3404470C2
Authority
DE
Germany
Prior art keywords
anthracyclinone
fce
glucuronide
sodium
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3404470A
Other languages
German (de)
English (en)
Other versions
DE3404470A1 (de
Inventor
Guiseppe Voghera It Cassinelli
Arpad Mailand/Milano It Grein
Sergio I-Bernareggio Mailand/Milano It Merli
Giovanni Mailand/Milano It Rivola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of DE3404470A1 publication Critical patent/DE3404470A1/de
Application granted granted Critical
Publication of DE3404470C2 publication Critical patent/DE3404470C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE19843404470 1983-04-16 1984-02-08 Anthracyclinonglucuronide, verfahren zu ihrer herstellung und sie enthaltende arzneimittel Granted DE3404470A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838310356A GB8310356D0 (en) 1983-04-16 1983-04-16 Anthracycline glucuronide

Publications (2)

Publication Number Publication Date
DE3404470A1 DE3404470A1 (de) 1984-10-18
DE3404470C2 true DE3404470C2 (pl) 1988-10-13

Family

ID=10541213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843404470 Granted DE3404470A1 (de) 1983-04-16 1984-02-08 Anthracyclinonglucuronide, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Country Status (4)

Country Link
JP (1) JPS59193899A (pl)
BE (1) BE898837A (pl)
DE (1) DE3404470A1 (pl)
GB (1) GB8310356D0 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981233A (en) * 1997-08-21 1999-11-09 Roche Vitamins Inc. Process for manufacturing a xylanase enzyme complex from pre-treated thin stillage of rye

Also Published As

Publication number Publication date
JPS59193899A (ja) 1984-11-02
DE3404470A1 (de) 1984-10-18
BE898837A (fr) 1984-05-30
GB8310356D0 (en) 1983-05-18

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C07H 15/24

8125 Change of the main classification

Ipc: C12N 1/20

D2 Grant after examination
8327 Change in the person/name/address of the patent owner

Owner name: FARMITALIA CARLO ERBA S.R.L., MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Free format text: KRAUS, W., DIPL.-CHEM. DR.RER.NAT. WEISERT, A., DIPL.-ING. DR.-ING. SPIES, J., DIPL.-PHYS., PAT.-ANWAELTE, 8000 MUENCHEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee