DE3375141D1 - Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use - Google Patents

Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use

Info

Publication number
DE3375141D1
DE3375141D1 DE8383305958T DE3375141T DE3375141D1 DE 3375141 D1 DE3375141 D1 DE 3375141D1 DE 8383305958 T DE8383305958 T DE 8383305958T DE 3375141 T DE3375141 T DE 3375141T DE 3375141 D1 DE3375141 D1 DE 3375141D1
Authority
DE
Germany
Prior art keywords
vinylthioacetamido
preparation
same
formulations containing
intermediates therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383305958T
Other languages
English (en)
Inventor
Wataru Nagata
Mitsuru Yoshioka
Yasuhiro Nishitani
Tsutomu Aoki
Toshiro Konoike
Tadatoshi Kubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57172907A external-priority patent/JPS5962596A/ja
Priority claimed from JP58128116A external-priority patent/JPS6019791A/ja
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3375141D1 publication Critical patent/DE3375141D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/535—Organo-phosphoranes
    • C07F9/5352—Phosphoranes containing the structure P=C-
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE8383305958T 1982-09-30 1983-09-30 Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use Expired DE3375141D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57172907A JPS5962596A (ja) 1982-09-30 1982-09-30 ビニルチオ化オキサセフアロスポリン誘導体
JP58128116A JPS6019791A (ja) 1983-07-13 1983-07-13 フルオロビニルチオオキサセフアロスポリン類

Publications (1)

Publication Number Publication Date
DE3375141D1 true DE3375141D1 (en) 1988-02-11

Family

ID=26463879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383305958T Expired DE3375141D1 (en) 1982-09-30 1983-09-30 Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use

Country Status (13)

Country Link
US (1) US4529721A (de)
EP (1) EP0107928B1 (de)
KR (1) KR900008552B1 (de)
AU (1) AU558772B2 (de)
CA (1) CA1219866A (de)
DE (1) DE3375141D1 (de)
DK (1) DK163000C (de)
ES (1) ES8600311A1 (de)
FI (1) FI74015C (de)
GB (2) GB2168349B (de)
IE (1) IE55977B1 (de)
NO (1) NO168478C (de)
PH (2) PH20013A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61130223A (ja) * 1984-11-28 1986-06-18 Shionogi & Co Ltd 抗菌性凍結乾燥製剤
KR960002856B1 (ko) * 1987-03-09 1996-02-27 오쓰까 세이야꾸 가부시끼가이샤 2-옥사-이소세펨 화합물, 이를 함유하는 조성물 및 이의 제조방법
EP0594583A1 (de) * 1990-01-12 1994-05-04 The Dow Chemical Company Zusammensetzung und verwendung von substituierten 3-thio-2-propynnitrilen als industrielles antimikrobikum
US5198445A (en) * 1990-01-12 1993-03-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials
US5126349A (en) * 1990-01-12 1992-06-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5157051A (en) * 1992-03-05 1992-10-20 The Dow Chemical Company Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents
US5155119A (en) * 1992-03-05 1992-10-13 The Dow Chemical Company 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials
US5206227A (en) * 1992-06-02 1993-04-27 The Dow Chemical Company Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials
US5958462A (en) * 1997-05-23 1999-09-28 Mclean; Linsey Therapeutic bath salts and method of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604738A (en) * 1977-07-28 1981-12-16 Yamanouchi Pharma Co Ltd 1,3-dithietane-2-carboxylic acid derivatives and the preparation thereof
DE2821639A1 (de) * 1978-05-18 1979-11-22 Hoechst Ag Neue thioenolaether, verfahren zu ihrer herstellung sowie ihre verwendung
GB2045233B (en) * 1979-03-23 1983-05-11 Erba Farmitalia Unsaturated 3-heterocyclylthiomethyl-7a-methoxy-7-acylamido-3-cephem-4-carboxylic acid derivatives
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
JPS56103185A (en) * 1980-01-22 1981-08-18 Shionogi & Co Ltd Malonamidoxa-dethia-cephem compound
US4458072A (en) * 1980-10-10 1984-07-03 Hoffmann-La Roche Inc. Acyl derivatives
FR2496666A1 (fr) * 1980-12-22 1982-06-25 Ici Pharma Nouveaux derives de cephalosporine et composition pharmaceutique les contenant

Also Published As

Publication number Publication date
IE832310L (en) 1984-03-30
IE55977B1 (en) 1991-03-13
PH20013A (en) 1986-08-28
NO168478C (no) 1992-02-26
KR900008552B1 (ko) 1990-11-24
GB2127825A (en) 1984-04-18
ES526130A0 (es) 1985-10-01
KR840006252A (ko) 1984-11-22
PH20224A (en) 1986-10-23
AU558772B2 (en) 1987-02-05
EP0107928A1 (de) 1984-05-09
GB2168349B (en) 1987-03-11
DK426683A (da) 1984-03-31
DK163000C (da) 1992-06-01
NO168478B (no) 1991-11-18
ES8600311A1 (es) 1985-10-01
GB2127825B (en) 1987-03-11
FI833348A0 (fi) 1983-09-20
FI74015C (fi) 1987-12-10
GB8326244D0 (en) 1983-11-02
US4529721A (en) 1985-07-16
GB8601753D0 (en) 1986-02-26
GB2168349A (en) 1986-06-18
AU1975283A (en) 1984-04-05
DK163000B (da) 1992-01-06
FI74015B (fi) 1987-08-31
EP0107928B1 (de) 1988-01-07
NO833521L (no) 1984-04-02
CA1219866A (en) 1987-03-31
DK426683D0 (da) 1983-09-19
FI833348A (fi) 1984-03-31

Similar Documents

Publication Publication Date Title
DE3175083D1 (en) Pharmaceutical compounds, their preparation and use
IL67472A (en) Oxabicycloaliphatic derivatives,their preparation and their use as herbicides
DE3260034D1 (en) Dichloroquinoline derivatives, their preparation and their use as herbicides
ZA812708B (en) Ss-lactam compounds, their preparation and use
DE3367607D1 (en) Basic compounds, their preparation and their use
IL69227A (en) N-phenylpyrazole derivatives,their preparation and their use as herbicides
DE3375141D1 (en) Vinylthioacetamido oxacephalosporin derivatives, and intermediates therefor, their preparation, formulations containing the same and their antibacterial use
IL64845A0 (en) Substituted phenylsulfonylurea derivatives,their preparation and their use as herbicides
IL69323A0 (en) Substituted 3-trichloromethyl-1,2,4-thiadiazol-5-yl-oxyacetamides,their preparation and their use as herbicides
IL69321A0 (en) Substituted 3-trihalogenomethyl-1,2,4-thiadiazol-5-yl-oxyacetamides,their preparation and their use as herbicides
DE3366497D1 (en) Antibacterial agents, their preparation and use
DE3365480D1 (en) Oxacephalosporin derivatives, their preparation and use
DE3071198D1 (en) Acridinones, their preparation and use; intermediates and their preparation
DE3269621D1 (en) Phenoxyphenyl-aminocarboxylic-acid derivatives, their preparation, compositions containing them and their use
IL65039A0 (en) Substituted tetrahydropyrimidinone derivatives,their preparation and their use as herbicides
IL76224A0 (en) Substituted carbonylphenylsulphonylguanidines,their preparation and their use as herbicides
CY1521A (en) Substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols,preparation and use thereof
IL76213A0 (en) Substituted arylsulphonylguanidines,their preparation and their use as herbicides
DE3166164D1 (en) Anthraquinone-azo compounds, their preparation and their use
IL66935A0 (en) Substituted 6-phenoxypyrid-2-ylmethyl vinylcyclopropane-carboxylates,their preparation and their use as pesticides
IL68815A0 (en) Trifluoromethylphenoxy-phenyl derivatives,their preparation and their use as herbicides
IL70380A0 (en) Cycloalkenyl derivatives,their preparation and use as herbicides
DE3069781D1 (en) 2-amino-benzoic-acid derivatives, their preparation and their use as medicines or intermediates
IL69403A0 (en) Azolyl-ketoenamines,their preparation and their use as intermediates
IL65561A0 (en) Substituted carbamoyloximino-tetrahydrothiophenes,their preparation and their use as pesticides

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee