DE3314479A1 - Pleuromutilin-derivate, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika - Google Patents

Pleuromutilin-derivate, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika

Info

Publication number
DE3314479A1
DE3314479A1 DE19833314479 DE3314479A DE3314479A1 DE 3314479 A1 DE3314479 A1 DE 3314479A1 DE 19833314479 DE19833314479 DE 19833314479 DE 3314479 A DE3314479 A DE 3314479A DE 3314479 A1 DE3314479 A1 DE 3314479A1
Authority
DE
Germany
Prior art keywords
formula
compounds
amino
alkyl group
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833314479
Other languages
German (de)
English (en)
Inventor
Heinz Dr. 1180 Wien Berner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Sandoz Patent GmbH
Original Assignee
Sandoz AG
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, Sandoz Patent GmbH filed Critical Sandoz AG
Publication of DE3314479A1 publication Critical patent/DE3314479A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19833314479 1982-04-28 1983-04-21 Pleuromutilin-derivate, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika Withdrawn DE3314479A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT165182 1982-04-28
AT427082 1982-11-24

Publications (1)

Publication Number Publication Date
DE3314479A1 true DE3314479A1 (de) 1983-11-03

Family

ID=25596422

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833314479 Withdrawn DE3314479A1 (de) 1982-04-28 1983-04-21 Pleuromutilin-derivate, verfahren zu ihrer herstellung und ihre verwendung als pharmazeutika

Country Status (12)

Country Link
AU (1) AU1393783A (it)
DE (1) DE3314479A1 (it)
DK (1) DK185683A (it)
ES (1) ES8406431A1 (it)
FI (1) FI831367L (it)
FR (1) FR2526019A1 (it)
GB (1) GB2121035A (it)
IL (1) IL68508A0 (it)
IT (1) IT1197634B (it)
NL (1) NL8301448A (it)
PT (1) PT76598B (it)
SE (1) SE8302345L (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004414A1 (en) * 2000-07-11 2002-01-17 Biochemie Gesellschaft M.B.H. Pleuromutilin derivatives having antibacterial activity

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3560511D1 (en) * 1984-02-17 1987-10-01 Sandoz Ag Pleuromutilin derivatives, process for their preparation and their use
HU208115B (en) * 1989-10-03 1993-08-30 Biochemie Gmbh New process for producting pleuromutilin derivatives
GB0218578D0 (en) 2002-08-09 2002-09-18 Glaxo Group Ltd Novel method
CN104447450B (zh) * 2014-07-08 2016-09-28 南通大学 半胱氨酸酰胺类截短侧耳素衍生物及制备方法与医药用途
CN104961666B (zh) * 2014-07-08 2017-04-12 南通大学 2‑巯基乙酰胺类截短侧耳素衍生物及制备方法与医药用途
CN109384698B (zh) * 2017-08-04 2022-07-08 保定加合精细化工有限公司 一种双萜烯类畜禽用抗生素的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT301752B (de) * 1969-07-21 1972-09-25 Biochemie Gmbh Verfahren zur Herstellung neuer Pleuromutilin-Derivate
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins
IE44428B1 (en) * 1975-09-30 1981-12-02 Squibb & Sons Inc New derivatives of pleuromutilin and compositions containig same
DE2823712C2 (de) * 1978-05-31 1987-04-09 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur Herstellung von Pleuromutilin-Derivaten

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002004414A1 (en) * 2000-07-11 2002-01-17 Biochemie Gesellschaft M.B.H. Pleuromutilin derivatives having antibacterial activity
NO329091B1 (no) * 2000-07-11 2010-08-23 Nabriva Therapeutics Forschungs Gmbh Pleuromutilinderivater som har antibakteriell aktivitet, anvendelse derav og farmasøytisk sammensetning omfattende en slik forbindelse

Also Published As

Publication number Publication date
ES521847A0 (es) 1984-08-01
FR2526019A1 (fr) 1983-11-04
PT76598A (en) 1983-05-01
FI831367A0 (fi) 1983-04-21
GB2121035A (en) 1983-12-14
DK185683A (da) 1983-10-29
SE8302345L (sv) 1983-10-29
PT76598B (en) 1986-01-24
IT8348162A0 (it) 1983-04-27
IL68508A0 (en) 1983-07-31
AU1393783A (en) 1983-11-03
IT1197634B (it) 1988-12-06
FR2526019B1 (it) 1985-04-26
SE8302345D0 (sv) 1983-04-26
ES8406431A1 (es) 1984-08-01
FI831367L (fi) 1983-10-29
DK185683D0 (da) 1983-04-26
GB8311194D0 (en) 1983-06-02
NL8301448A (nl) 1983-11-16

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Legal Events

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8139 Disposal/non-payment of the annual fee