DE3234253A1 - (11r)-11-desoxy-11-alkyl-6-oxo-pg-artige verbindungen - Google Patents

(11r)-11-desoxy-11-alkyl-6-oxo-pg-artige verbindungen

Info

Publication number
DE3234253A1
DE3234253A1 DE19823234253 DE3234253A DE3234253A1 DE 3234253 A1 DE3234253 A1 DE 3234253A1 DE 19823234253 DE19823234253 DE 19823234253 DE 3234253 A DE3234253 A DE 3234253A DE 3234253 A1 DE3234253 A1 DE 3234253A1
Authority
DE
Germany
Prior art keywords
radical
deoxy
formula
methyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19823234253
Other languages
German (de)
English (en)
Inventor
Douglas Ross Portage Mich. Morton jun.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DE3234253A1 publication Critical patent/DE3234253A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19823234253 1981-10-30 1982-09-15 (11r)-11-desoxy-11-alkyl-6-oxo-pg-artige verbindungen Withdrawn DE3234253A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/316,480 US4403100A (en) 1981-10-30 1981-10-30 (11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins

Publications (1)

Publication Number Publication Date
DE3234253A1 true DE3234253A1 (de) 1983-05-11

Family

ID=23229238

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19823234253 Withdrawn DE3234253A1 (de) 1981-10-30 1982-09-15 (11r)-11-desoxy-11-alkyl-6-oxo-pg-artige verbindungen

Country Status (6)

Country Link
US (1) US4403100A (enExample)
JP (1) JPS5888354A (enExample)
DE (1) DE3234253A1 (enExample)
FR (1) FR2515642A1 (enExample)
GB (1) GB2108960B (enExample)
IT (1) IT1149099B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
WO1992006684A1 (en) * 1990-10-18 1992-04-30 Syntex (Usa) Inc. A new use of enprostil
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
AU2009246573B2 (en) * 2008-05-15 2014-04-24 Allergan, Inc. Therapeutic substituted cyclopentanes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440361A (en) * 1972-07-24 1976-06-23 American Cyanamid Co 11-deoxyprostaglandins of the e and f series and the preparation thereof
US4124601A (en) * 1976-12-30 1978-11-07 The Upjohn Company Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds
US4223157A (en) * 1979-08-27 1980-09-16 The Upjohn Company 6-Keto-ωaryl-PGE1 compounds

Also Published As

Publication number Publication date
JPS5888354A (ja) 1983-05-26
US4403100A (en) 1983-09-06
FR2515642B1 (enExample) 1985-02-08
FR2515642A1 (fr) 1983-05-06
IT1149099B (it) 1986-12-03
GB2108960A (en) 1983-05-25
GB2108960B (en) 1985-09-04
IT8249218A0 (it) 1982-10-06

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: HENKEL, G., DR.PHIL. FEILER, L., DR.RER.NAT. HAENZ

8139 Disposal/non-payment of the annual fee