JPS5888354A - １１−デオキシ−１１−アルキル−６−オキソ−ｐｇｅ - Google Patents

１１−デオキシ−１１−アルキル−６−オキソ−ｐｇｅ

Info

Publication number
JPS5888354A
JPS5888354A JP57189384A JP18938482A JPS5888354A JP S5888354 A JPS5888354 A JP S5888354A JP 57189384 A JP57189384 A JP 57189384A JP 18938482 A JP18938482 A JP 18938482A JP S5888354 A JPS5888354 A JP S5888354A
Authority
JP
Japan
Prior art keywords
alkyl
hydrogen
phenyl
methyl
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57189384A
Other languages
English (en)
Japanese (ja)
Inventor
ダグラス・ロス・モ−トン・ジユニア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of JPS5888354A publication Critical patent/JPS5888354A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP57189384A 1981-10-30 1982-10-29 １１−デオキシ−１１−アルキル−６−オキソ−ｐｇｅ Pending JPS5888354A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/316,480 US4403100A (en) 1981-10-30 1981-10-30 (11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins
US316480 1981-10-30

Publications (1)

Publication Number Publication Date
JPS5888354A true JPS5888354A (ja) 1983-05-26

Family

ID=23229238

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57189384A Pending JPS5888354A (ja) 1981-10-30 1982-10-29 １１−デオキシ−１１−アルキル−６−オキソ−ｐｇｅ

Country Status (6)

Country Link
US (1) US4403100A (enExample)
JP (1) JPS5888354A (enExample)
DE (1) DE3234253A1 (enExample)
FR (1) FR2515642A1 (enExample)
GB (1) GB2108960B (enExample)
IT (1) IT1149099B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
WO1992006684A1 (en) * 1990-10-18 1992-04-30 Syntex (Usa) Inc. A new use of enprostil
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US8592413B2 (en) * 2008-05-15 2013-11-26 Allergan, Inc. Therapeutic substituted cyclopentanes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440361A (en) * 1972-07-24 1976-06-23 American Cyanamid Co 11-deoxyprostaglandins of the e and f series and the preparation thereof
US4124601A (en) * 1976-12-30 1978-11-07 The Upjohn Company Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds
US4223157A (en) * 1979-08-27 1980-09-16 The Upjohn Company 6-Keto-ωaryl-PGE1 compounds

Also Published As

Publication number Publication date
IT1149099B (it) 1986-12-03
FR2515642A1 (fr) 1983-05-06
GB2108960A (en) 1983-05-25
IT8249218A0 (it) 1982-10-06
GB2108960B (en) 1985-09-04
FR2515642B1 (enExample) 1985-02-08
US4403100A (en) 1983-09-06
DE3234253A1 (de) 1983-05-11

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