GB2108960B - 6-oxo-pge analogues - Google Patents

6-oxo-pge analogues

Info

Publication number
GB2108960B
GB2108960B GB08230364A GB8230364A GB2108960B GB 2108960 B GB2108960 B GB 2108960B GB 08230364 A GB08230364 A GB 08230364A GB 8230364 A GB8230364 A GB 8230364A GB 2108960 B GB2108960 B GB 2108960B
Authority
GB
United Kingdom
Prior art keywords
oxo
pge
analogues
pge analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08230364A
Other languages
English (en)
Other versions
GB2108960A (en
Inventor
Douglas Ross Morton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB2108960A publication Critical patent/GB2108960A/en
Application granted granted Critical
Publication of GB2108960B publication Critical patent/GB2108960B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB08230364A 1981-10-30 1982-10-25 6-oxo-pge analogues Expired GB2108960B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/316,480 US4403100A (en) 1981-10-30 1981-10-30 (11R)-11-Deoxy-11-alkyl-6-oxo-prostaglandins

Publications (2)

Publication Number Publication Date
GB2108960A GB2108960A (en) 1983-05-25
GB2108960B true GB2108960B (en) 1985-09-04

Family

ID=23229238

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08230364A Expired GB2108960B (en) 1981-10-30 1982-10-25 6-oxo-pge analogues

Country Status (6)

Country Link
US (1) US4403100A (enExample)
JP (1) JPS5888354A (enExample)
DE (1) DE3234253A1 (enExample)
FR (1) FR2515642A1 (enExample)
GB (1) GB2108960B (enExample)
IT (1) IT1149099B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
WO1992006684A1 (en) * 1990-10-18 1992-04-30 Syntex (Usa) Inc. A new use of enprostil
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US8592413B2 (en) * 2008-05-15 2013-11-26 Allergan, Inc. Therapeutic substituted cyclopentanes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440361A (en) * 1972-07-24 1976-06-23 American Cyanamid Co 11-deoxyprostaglandins of the e and f series and the preparation thereof
US4124601A (en) * 1976-12-30 1978-11-07 The Upjohn Company Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds
US4223157A (en) * 1979-08-27 1980-09-16 The Upjohn Company 6-Keto-ωaryl-PGE1 compounds

Also Published As

Publication number Publication date
IT1149099B (it) 1986-12-03
FR2515642A1 (fr) 1983-05-06
GB2108960A (en) 1983-05-25
IT8249218A0 (it) 1982-10-06
JPS5888354A (ja) 1983-05-26
FR2515642B1 (enExample) 1985-02-08
US4403100A (en) 1983-09-06
DE3234253A1 (de) 1983-05-11

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee