DE3168037D1 - Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient - Google Patents

Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient

Info

Publication number
DE3168037D1
DE3168037D1 DE8181303816T DE3168037T DE3168037D1 DE 3168037 D1 DE3168037 D1 DE 3168037D1 DE 8181303816 T DE8181303816 T DE 8181303816T DE 3168037 T DE3168037 T DE 3168037T DE 3168037 D1 DE3168037 D1 DE 3168037D1
Authority
DE
Germany
Prior art keywords
rhodanine derivatives
preparation
active ingredient
reductase inhibitor
aldose reductase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181303816T
Other languages
English (en)
Inventor
Tanouchi Tadao
Kawamura Masanori
Ajima Akio
Mohri Tetsuya
Hayashi Masaki
Terashima Hiroshi
Hirata Fumio
Morimura Takeshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3168037D1 publication Critical patent/DE3168037D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE8181303816T 1980-08-22 1981-08-21 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient Expired DE3168037D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55115641A JPS5740478A (en) 1980-08-22 1980-08-22 Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative

Publications (1)

Publication Number Publication Date
DE3168037D1 true DE3168037D1 (en) 1985-02-14

Family

ID=14667662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181303816T Expired DE3168037D1 (en) 1980-08-22 1981-08-21 Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient

Country Status (4)

Country Link
US (2) US4464382A (de)
EP (1) EP0047109B1 (de)
JP (1) JPS5740478A (de)
DE (1) DE3168037D1 (de)

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JP6976047B2 (ja) * 2015-08-28 2021-12-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 エパルレスタットを調製する方法
CN116854648A (zh) * 2016-05-25 2023-10-10 华创合成制药股份有限公司 一种新型醛糖还原酶抑制类化合物及应用
CN106045987B (zh) * 2016-06-21 2019-04-23 广东工业大学 一种具有多功能近红外荧光磁性纳米微粒及其制备和应用
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Also Published As

Publication number Publication date
US4831045A (en) 1989-05-16
JPS5740478A (en) 1982-03-06
EP0047109A1 (de) 1982-03-10
JPS6251955B2 (de) 1987-11-02
US4464382A (en) 1984-08-07
EP0047109B1 (de) 1985-01-02

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