DE3133293A1 - Derivate von aminothiolen, verfahren zu deren herstellung, deren anwendung und solche derivate enthaltende pharmazeutische zubereitungen - Google Patents

Derivate von aminothiolen, verfahren zu deren herstellung, deren anwendung und solche derivate enthaltende pharmazeutische zubereitungen

Info

Publication number
DE3133293A1
DE3133293A1 DE19813133293 DE3133293A DE3133293A1 DE 3133293 A1 DE3133293 A1 DE 3133293A1 DE 19813133293 DE19813133293 DE 19813133293 DE 3133293 A DE3133293 A DE 3133293A DE 3133293 A1 DE3133293 A1 DE 3133293A1
Authority
DE
Germany
Prior art keywords
radical
carbon atoms
linear
branched
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19813133293
Other languages
German (de)
English (en)
Inventor
Claude Blanmont Gillet
Georges Bruxelles Lambelin
Albert Chaumont-Gistoux Lenaerts
Paul Grez-Doiceau Niebes
Joseph Dion-Valmont Roba
Michel Limal Snyers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of DE3133293A1 publication Critical patent/DE3133293A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19813133293 1980-08-29 1981-08-22 Derivate von aminothiolen, verfahren zu deren herstellung, deren anwendung und solche derivate enthaltende pharmazeutische zubereitungen Withdrawn DE3133293A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU82738A LU82738A1 (fr) 1980-08-29 1980-08-29 Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives

Publications (1)

Publication Number Publication Date
DE3133293A1 true DE3133293A1 (de) 1982-04-08

Family

ID=19729472

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813133293 Withdrawn DE3133293A1 (de) 1980-08-29 1981-08-22 Derivate von aminothiolen, verfahren zu deren herstellung, deren anwendung und solche derivate enthaltende pharmazeutische zubereitungen

Country Status (18)

Country Link
JP (1) JPS5798255A (es)
AU (1) AU7465481A (es)
BE (1) BE890116A (es)
DE (1) DE3133293A1 (es)
DK (1) DK382281A (es)
ES (1) ES8307735A1 (es)
FI (1) FI812640L (es)
FR (1) FR2489325A1 (es)
GB (1) GB2083036A (es)
GR (1) GR74348B (es)
IL (1) IL63664A0 (es)
IT (1) IT1137642B (es)
LU (1) LU82738A1 (es)
NL (1) NL8103993A (es)
NO (1) NO812944L (es)
PT (1) PT73593B (es)
SE (1) SE8104958L (es)
ZA (1) ZA815912B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8405896D0 (en) * 1984-03-07 1984-04-11 Sandoz Ltd Organic compounds
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2505870A (en) * 1947-05-09 1950-05-02 Phillips Petroleum Co Secondary and tertiary alkylthiol amines and their production
US3337625A (en) * 1961-09-18 1967-08-22 Lilly Co Eli Amino-acetylenic compounds
US3312732A (en) * 1962-02-28 1967-04-04 Monsanto Res Corp Aminoalkyl aminoalkanethiols
US3356730A (en) * 1964-11-25 1967-12-05 Monsanto Res Corp Mercaptoalkyl oxyalkyl amines
GB1138738A (en) * 1966-12-01 1969-01-01 Eastman Kodak Co Aziridine derivatives
US3622676A (en) * 1968-11-20 1971-11-23 Constance Anthony D Alonzo Smoking suppression
CA992105A (en) * 1970-03-26 1976-06-29 Exxon Research And Engineering Company Polythioethers formed by anionic ring opening of episulfides
BE789629A (fr) * 1971-10-05 1973-04-03 Sandoz Sa Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
CH632906A5 (en) * 1976-08-09 1982-11-15 Givaudan & Cie Sa Use of bifunctional N,S-compounds as flavourings

Also Published As

Publication number Publication date
BE890116A (fr) 1982-03-01
DK382281A (da) 1982-03-01
IL63664A0 (en) 1981-11-30
FR2489325A1 (fr) 1982-03-05
AU7465481A (en) 1982-03-04
IT1137642B (it) 1986-09-10
JPS5798255A (en) 1982-06-18
ES505037A0 (es) 1983-08-16
PT73593B (fr) 1982-11-10
FI812640L (fi) 1982-03-01
NL8103993A (nl) 1982-03-16
LU82738A1 (fr) 1982-05-10
ZA815912B (en) 1982-08-25
ES8307735A1 (es) 1983-08-16
NO812944L (no) 1982-03-01
IT8123611A0 (it) 1981-08-24
GB2083036A (en) 1982-03-17
PT73593A (fr) 1981-09-01
SE8104958L (sv) 1982-03-01
GR74348B (es) 1984-06-26

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8130 Withdrawal