FR2489325A1 - Derives d'aminothiols, leur preparation et utilisation ainsi que compositions contenant ces derives - Google Patents

Derives d'aminothiols, leur preparation et utilisation ainsi que compositions contenant ces derives Download PDF

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Publication number
FR2489325A1
FR2489325A1 FR8116512A FR8116512A FR2489325A1 FR 2489325 A1 FR2489325 A1 FR 2489325A1 FR 8116512 A FR8116512 A FR 8116512A FR 8116512 A FR8116512 A FR 8116512A FR 2489325 A1 FR2489325 A1 FR 2489325A1
Authority
FR
France
Prior art keywords
linear
branched
formula
radical
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8116512A
Other languages
English (en)
French (fr)
Inventor
Michel Snyers
Claude Gillet
Joseph Roba
Paul Niebes
Georges Lambelin
Albert Lenaerts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of FR2489325A1 publication Critical patent/FR2489325A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8116512A 1980-08-29 1981-08-28 Derives d'aminothiols, leur preparation et utilisation ainsi que compositions contenant ces derives Withdrawn FR2489325A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU82738A LU82738A1 (fr) 1980-08-29 1980-08-29 Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives

Publications (1)

Publication Number Publication Date
FR2489325A1 true FR2489325A1 (fr) 1982-03-05

Family

ID=19729472

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8116512A Withdrawn FR2489325A1 (fr) 1980-08-29 1981-08-28 Derives d'aminothiols, leur preparation et utilisation ainsi que compositions contenant ces derives

Country Status (18)

Country Link
JP (1) JPS5798255A (es)
AU (1) AU7465481A (es)
BE (1) BE890116A (es)
DE (1) DE3133293A1 (es)
DK (1) DK382281A (es)
ES (1) ES8307735A1 (es)
FI (1) FI812640L (es)
FR (1) FR2489325A1 (es)
GB (1) GB2083036A (es)
GR (1) GR74348B (es)
IL (1) IL63664A0 (es)
IT (1) IT1137642B (es)
LU (1) LU82738A1 (es)
NL (1) NL8103993A (es)
NO (1) NO812944L (es)
PT (1) PT73593B (es)
SE (1) SE8104958L (es)
ZA (1) ZA815912B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8405896D0 (en) * 1984-03-07 1984-04-11 Sandoz Ltd Organic compounds
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2505870A (en) * 1947-05-09 1950-05-02 Phillips Petroleum Co Secondary and tertiary alkylthiol amines and their production
US3312732A (en) * 1962-02-28 1967-04-04 Monsanto Res Corp Aminoalkyl aminoalkanethiols
US3337625A (en) * 1961-09-18 1967-08-22 Lilly Co Eli Amino-acetylenic compounds
US3352918A (en) * 1964-11-25 1967-11-14 Monsanto Res Corp Diamine oxyalkyl compounds
FR1504888A (fr) * 1966-12-01 1967-12-08 Eastman Kodak Co Nouveau tannant de la gélatine et procédé pour sa préparation
DE2114124A1 (de) * 1970-03-26 1971-10-14 Esso Res And Engineering Co Verfahren zur Herstellung von Thioaetherverbindungen
US3622676A (en) * 1968-11-20 1971-11-23 Constance Anthony D Alonzo Smoking suppression
FR2157828A1 (es) * 1971-10-05 1973-06-08 Sandoz Sa
FR2392610A1 (fr) * 1976-08-09 1978-12-29 Givaudan & Cie Sa Compositions aromatisantes

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2505870A (en) * 1947-05-09 1950-05-02 Phillips Petroleum Co Secondary and tertiary alkylthiol amines and their production
US3337625A (en) * 1961-09-18 1967-08-22 Lilly Co Eli Amino-acetylenic compounds
US3312732A (en) * 1962-02-28 1967-04-04 Monsanto Res Corp Aminoalkyl aminoalkanethiols
US3352918A (en) * 1964-11-25 1967-11-14 Monsanto Res Corp Diamine oxyalkyl compounds
FR1504888A (fr) * 1966-12-01 1967-12-08 Eastman Kodak Co Nouveau tannant de la gélatine et procédé pour sa préparation
US3622676A (en) * 1968-11-20 1971-11-23 Constance Anthony D Alonzo Smoking suppression
DE2114124A1 (de) * 1970-03-26 1971-10-14 Esso Res And Engineering Co Verfahren zur Herstellung von Thioaetherverbindungen
FR2157828A1 (es) * 1971-10-05 1973-06-08 Sandoz Sa
FR2392610A1 (fr) * 1976-08-09 1978-12-29 Givaudan & Cie Sa Compositions aromatisantes

Non-Patent Citations (18)

* Cited by examiner, † Cited by third party
Title
BULLETIN SOCIETE CHIMIQUE FRANCE, no. 10, 1963, pages 2160-2162; *
CHEMICAL ABSTRACTS, vol. 55, no. 11, 29 mai 1961, col. 10697d-e, Columbus Ohio (USA); *
CHEMICAL ABSTRACTS, vol. 56, no. 5, 5 mars 1962, cols. 5363i-5364a, Columbus Ohio (USA); *
CHEMICAL ABSTRACTS, vol. 56, no. 7, 2 avril 1962, col. 7664-f, Columbus Ohio (USA); *
CHEMICAL ABSTRACTS, vol. 56, no. 9, 30 avril 1962, col. 10516c-d, Columbus Ohio (USA); *
CHEMISCHES ZENTRALBLATT, no. 52, 22 décembre 1965, no. 1783, Weinheim, Berlin (DE); *
CHIMIE THERAPEUTIQUE, no. 5, septembre-octobre 1970, pages 312-317, Paris (FR); *
JOURNAL OF AMERICAN CHEM. SOCIETY, vol. 69, novembre 1947, pages 2672-2674, Washington, D.C. (USA); *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 11, juillet 1968, pages 824-829, Washington, D.C. (USA); *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 15, no. 9, 1972, pages 968-975, Washington, D.C. (USA); *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 15, no. 9, 1972, pages 976-978, Washington, D.C. (USA); *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 8, novembre 1965, pages 762-766, Washington, D.C. (USA); *
JOURNAL OF MEDICINAL CHEMISTRY, vol. 9, mai 1966, pages 391-394, Washington, D.C. (USA); *
JOURNAL OF ORGANIC CHEMISTRY, vol. 29, avril 1964, pages 974-975, Washington, D.C. (USA); *
JOURNAL OF ORGANIC CHEMISTRY, vol. 30, novembre 1965, pages 3689-3696, Washington, D.C. (USA); *
JOURNAL OF ORGANIC CHEMISTRY, vol. 36, no. 19, 1971, pages 2735-2739, Washington, D.C. (USA); *
JOURNAL OF PHARMACEUTICAL SCIENCES; vol. 51, no. 11, novembre 1962, pages 1098-1101, Washington, D.C. (USA); *
UNLISTED DRUGS, vol. 18, no. 5, mai 1966, page 47; *

Also Published As

Publication number Publication date
BE890116A (fr) 1982-03-01
DK382281A (da) 1982-03-01
IL63664A0 (en) 1981-11-30
DE3133293A1 (de) 1982-04-08
AU7465481A (en) 1982-03-04
IT1137642B (it) 1986-09-10
JPS5798255A (en) 1982-06-18
ES505037A0 (es) 1983-08-16
PT73593B (fr) 1982-11-10
FI812640L (fi) 1982-03-01
NL8103993A (nl) 1982-03-16
LU82738A1 (fr) 1982-05-10
ZA815912B (en) 1982-08-25
ES8307735A1 (es) 1983-08-16
NO812944L (no) 1982-03-01
IT8123611A0 (it) 1981-08-24
GB2083036A (en) 1982-03-17
PT73593A (fr) 1981-09-01
SE8104958L (sv) 1982-03-01
GR74348B (es) 1984-06-26

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Legal Events

Date Code Title Description
RE Withdrawal of published application