DE3060097D1 - Indolizine derivatives, process for their preparation and their therapeutical use - Google Patents
Indolizine derivatives, process for their preparation and their therapeutical useInfo
- Publication number
- DE3060097D1 DE3060097D1 DE8080870035T DE3060097T DE3060097D1 DE 3060097 D1 DE3060097 D1 DE 3060097D1 DE 8080870035 T DE8080870035 T DE 8080870035T DE 3060097 T DE3060097 T DE 3060097T DE 3060097 D1 DE3060097 D1 DE 3060097D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- therapeutical use
- indolizine derivatives
- indolizine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7923599 | 1979-07-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3060097D1 true DE3060097D1 (en) | 1982-01-28 |
Family
ID=10506339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8080870035T Expired DE3060097D1 (en) | 1979-07-06 | 1980-06-30 | Indolizine derivatives, process for their preparation and their therapeutical use |
Country Status (24)
Country | Link |
---|---|
US (1) | US4400387A (de) |
EP (1) | EP0022762B1 (de) |
JP (1) | JPS5618979A (de) |
AR (1) | AR225314A1 (de) |
AT (1) | AT375078B (de) |
AU (1) | AU529725B2 (de) |
CA (1) | CA1153379A (de) |
DD (1) | DD151940A5 (de) |
DE (1) | DE3060097D1 (de) |
DK (1) | DK146962C (de) |
ES (1) | ES493139A0 (de) |
FI (1) | FI67217C (de) |
GR (1) | GR69280B (de) |
HU (1) | HU182151B (de) |
IE (1) | IE49994B1 (de) |
IN (1) | IN151594B (de) |
NO (1) | NO153496C (de) |
NZ (1) | NZ193926A (de) |
OA (1) | OA06563A (de) |
PL (1) | PL125597B1 (de) |
PT (1) | PT71424A (de) |
SU (1) | SU993817A3 (de) |
YU (1) | YU171880A (de) |
ZA (1) | ZA803434B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6103702A (en) * | 1999-05-24 | 2000-08-15 | Board Of Trustees Of The University Of Illinois | Use of adenosine deaminase inhibitors to treat systemic inflammatory response syndrome |
WO2001007054A1 (en) * | 1999-07-22 | 2001-02-01 | Supergen, Inc. | Methods for treating autoimmune diseases |
FR2805460A1 (fr) * | 2000-02-25 | 2001-08-31 | Oreal | Compositions de teinture des fibres keratiniques contenant des derives d'indolizine cationiques et procede de teinture |
FR2838123B1 (fr) * | 2002-04-04 | 2005-06-10 | Sanofi Synthelabo | Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf |
JP4048166B2 (ja) * | 2002-11-18 | 2008-02-13 | 三井製糖株式会社 | 血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料 |
FR2859997B1 (fr) * | 2003-09-18 | 2006-02-03 | Sanofi Synthelabo | Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant. |
AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
FR2896247B1 (fr) | 2006-01-13 | 2008-02-29 | Sanofi Aventis Sa | Composes dimeres agonistes des recepteurs des fgfs (fgfrs), leur procede de preparation et leur application en therapeutique |
CA2755132C (en) | 2009-03-31 | 2018-02-13 | Kissei Pharmaceutical Co., Ltd. | Indolizine derivative and use thereof for medical purposes |
US20100261666A1 (en) * | 2009-04-14 | 2010-10-14 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis |
JP5906191B2 (ja) * | 2010-09-29 | 2016-04-20 | キッセイ薬品工業株式会社 | (アザ)インドリジン誘導体及びその医薬用途 |
SG11201802010QA (en) * | 2015-09-10 | 2018-04-27 | Jiangsu Atom Bioscience And Pharmaceutical Co Ltd | A group of compounds used for the treatment or prevention of hyperuricemia or gout |
WO2018090921A1 (zh) | 2016-11-16 | 2018-05-24 | 江苏新元素医药科技有限公司 | Urat1抑制剂及其应用 |
CN108084186B (zh) * | 2016-11-16 | 2021-06-25 | 江苏新元素医药科技有限公司 | Urat1抑制剂及其应用 |
CN114213331A (zh) * | 2017-05-26 | 2022-03-22 | 江苏新元素医药科技有限公司 | 一类urat1抑制剂及其应用 |
WO2018214961A1 (zh) * | 2017-05-26 | 2018-11-29 | 江苏新元素医药科技有限公司 | 促尿酸排泄的urat1抑制剂 |
JP7266901B2 (ja) * | 2018-01-19 | 2023-05-01 | エボポイント、バイオサイエンシズ、カンパニー、リミテッド | 複素環式化合物、調製方法及びその医薬的な応用 |
CN110283167A (zh) * | 2018-11-14 | 2019-09-27 | 贵州省中国科学院天然产物化学重点实验室 | 一种抗心率失常药物布托普洛嗪的制备方法 |
WO2022169974A1 (en) | 2021-02-05 | 2022-08-11 | Nexys Therapeutics, Inc. | Inhibitors of urat1 and pharmaceutical uses thereof |
WO2023221078A1 (en) * | 2022-05-20 | 2023-11-23 | Jiangsu Atom Bioscience And Pharmaceutical Co., Ltd. | Solid forms of a compound for treating or preventing hyperuricemia or gout |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU430639A1 (ru) | 1972-06-05 | 1978-02-28 | Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова | Способ получени 1-пиридилиндолизинов |
GB1518443A (en) * | 1976-02-19 | 1978-07-19 | Labaz | Indolizine derivatives and process for preparing the same |
FI61030C (fi) | 1976-02-19 | 1982-05-10 | Sanofi Sa | Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat |
-
1980
- 1980-06-04 NZ NZ193926A patent/NZ193926A/en unknown
- 1980-06-09 ZA ZA00803434A patent/ZA803434B/xx unknown
- 1980-06-10 GR GR62170A patent/GR69280B/el unknown
- 1980-06-20 PT PT71424A patent/PT71424A/pt unknown
- 1980-06-20 AU AU59487/80A patent/AU529725B2/en not_active Ceased
- 1980-06-26 IN IN738/CAL/80A patent/IN151594B/en unknown
- 1980-06-30 EP EP80870035A patent/EP0022762B1/de not_active Expired
- 1980-06-30 IE IE1349/80A patent/IE49994B1/en unknown
- 1980-06-30 US US06/164,838 patent/US4400387A/en not_active Expired - Lifetime
- 1980-06-30 DE DE8080870035T patent/DE3060097D1/de not_active Expired
- 1980-07-01 YU YU01718/80A patent/YU171880A/xx unknown
- 1980-07-02 OA OA57151A patent/OA06563A/xx unknown
- 1980-07-02 AR AR281618A patent/AR225314A1/es active
- 1980-07-03 SU SU802942500A patent/SU993817A3/ru active
- 1980-07-04 NO NO802015A patent/NO153496C/no unknown
- 1980-07-04 CA CA000355421A patent/CA1153379A/en not_active Expired
- 1980-07-04 HU HU801674A patent/HU182151B/hu not_active IP Right Cessation
- 1980-07-04 ES ES493139A patent/ES493139A0/es active Granted
- 1980-07-04 DD DD80222415A patent/DD151940A5/de unknown
- 1980-07-04 JP JP9216080A patent/JPS5618979A/ja active Pending
- 1980-07-04 PL PL1980225479A patent/PL125597B1/pl unknown
- 1980-07-04 DK DK291180A patent/DK146962C/da not_active IP Right Cessation
- 1980-07-07 FI FI802165A patent/FI67217C/fi not_active IP Right Cessation
- 1980-07-07 AT AT0354380A patent/AT375078B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATA354380A (de) | 1983-11-15 |
IE801349L (en) | 1981-01-06 |
NO153496B (no) | 1985-12-23 |
HU182151B (en) | 1983-12-28 |
AT375078B (de) | 1984-06-25 |
CA1153379A (en) | 1983-09-06 |
NZ193926A (en) | 1984-05-31 |
NO153496C (no) | 1986-05-14 |
PT71424A (en) | 1980-07-01 |
GR69280B (de) | 1982-05-13 |
EP0022762B1 (de) | 1981-11-25 |
EP0022762A1 (de) | 1981-01-21 |
ZA803434B (en) | 1981-05-27 |
NO802015L (no) | 1981-01-07 |
FI67217C (fi) | 1985-02-11 |
SU993817A3 (ru) | 1983-01-30 |
DK291180A (da) | 1981-01-07 |
YU171880A (en) | 1983-10-31 |
IE49994B1 (en) | 1986-01-22 |
IN151594B (de) | 1983-06-04 |
DD151940A5 (de) | 1981-11-11 |
FI67217B (fi) | 1984-10-31 |
DK146962C (da) | 1984-08-06 |
PL225479A1 (de) | 1981-10-30 |
US4400387A (en) | 1983-08-23 |
ES8105710A1 (es) | 1981-06-16 |
DK146962B (da) | 1984-02-27 |
AU529725B2 (en) | 1983-06-16 |
AU5948780A (en) | 1981-01-15 |
ES493139A0 (es) | 1981-06-16 |
JPS5618979A (en) | 1981-02-23 |
OA06563A (fr) | 1981-07-31 |
FI802165A (fi) | 1981-01-07 |
AR225314A1 (es) | 1982-03-15 |
PL125597B1 (en) | 1983-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |