DE3013502C2 - [2''-(Trifluormethyl)-phenthiazin-10''-yl-(n-prop-3'''ylpiperazin-4''''-yläth-2'''''-yl)]-ester, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel - Google Patents

[2''-(Trifluormethyl)-phenthiazin-10''-yl-(n-prop-3'''ylpiperazin-4''''-yläth-2'''''-yl)]-ester, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel

Info

Publication number
DE3013502C2
DE3013502C2 DE3013502A DE3013502A DE3013502C2 DE 3013502 C2 DE3013502 C2 DE 3013502C2 DE 3013502 A DE3013502 A DE 3013502A DE 3013502 A DE3013502 A DE 3013502A DE 3013502 C2 DE3013502 C2 DE 3013502C2
Authority
DE
Germany
Prior art keywords
trifluoromethyl
prop
ylpiperazin
ester
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3013502A
Other languages
German (de)
English (en)
Other versions
DE3013502A1 (de
Inventor
József Dr. Budapest Borsy
Ildikó Dr. Király
Lajos Dr. Toldy
István Dr. Tóth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EGYT GYOGYSZERVEGYESZETI GYAR BUDAPEST HU
Original Assignee
EGYT GYOGYSZERVEGYESZETI GYAR BUDAPEST HU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EGYT GYOGYSZERVEGYESZETI GYAR BUDAPEST HU filed Critical EGYT GYOGYSZERVEGYESZETI GYAR BUDAPEST HU
Publication of DE3013502A1 publication Critical patent/DE3013502A1/de
Application granted granted Critical
Publication of DE3013502C2 publication Critical patent/DE3013502C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE3013502A 1979-04-06 1980-04-08 [2''-(Trifluormethyl)-phenthiazin-10''-yl-(n-prop-3'''ylpiperazin-4''''-yläth-2'''''-yl)]-ester, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel Expired DE3013502C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79GO1442A HU179190B (en) 1979-04-06 1979-04-06 Process for preparing new phenthiazine derivatives

Publications (2)

Publication Number Publication Date
DE3013502A1 DE3013502A1 (de) 1980-10-16
DE3013502C2 true DE3013502C2 (de) 1985-02-07

Family

ID=10996889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3013502A Expired DE3013502C2 (de) 1979-04-06 1980-04-08 [2''-(Trifluormethyl)-phenthiazin-10''-yl-(n-prop-3'''ylpiperazin-4''''-yläth-2'''''-yl)]-ester, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel

Country Status (16)

Country Link
JP (1) JPS6043345B2 (es)
AT (1) AT375355B (es)
BE (1) BE882535A (es)
CA (1) CA1128940A (es)
CH (1) CH643843A5 (es)
CS (1) CS214704B2 (es)
DD (1) DD150060A5 (es)
DE (1) DE3013502C2 (es)
ES (1) ES8103077A1 (es)
FR (1) FR2453164A1 (es)
GB (1) GB2047694B (es)
HU (1) HU179190B (es)
IT (1) IT1148812B (es)
PL (1) PL127329B1 (es)
SU (1) SU925250A3 (es)
YU (1) YU42663B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471116A (en) * 1982-07-28 1984-09-11 Hoffmann-La Roche Inc. Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines
JPH0568560U (ja) * 1991-11-05 1993-09-17 理照 大島 握力強化用具
JP3932785B2 (ja) 1999-08-25 2007-06-20 株式会社村田製作所 圧電体の製造方法
US20060111346A1 (en) * 2004-11-23 2006-05-25 Fazix Corporation. Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL120362C (es) * 1961-04-26

Also Published As

Publication number Publication date
DD150060A5 (de) 1981-08-12
YU93380A (en) 1983-01-21
GB2047694A (en) 1980-12-03
JPS6043345B2 (ja) 1985-09-27
ATA184080A (de) 1983-12-15
ES490315A0 (es) 1981-02-16
BE882535A (fr) 1980-09-30
PL223267A1 (es) 1981-01-30
PL127329B1 (en) 1983-10-31
AT375355B (de) 1984-07-25
FR2453164A1 (fr) 1980-10-31
IT8021186A0 (it) 1980-04-04
CS214704B2 (en) 1982-05-28
CH643843A5 (de) 1984-06-29
GB2047694B (en) 1983-02-02
SU925250A3 (ru) 1982-04-30
DE3013502A1 (de) 1980-10-16
FR2453164B1 (es) 1983-04-15
ES8103077A1 (es) 1981-02-16
HU179190B (en) 1982-09-28
CA1128940A (en) 1982-08-03
YU42663B (en) 1988-10-31
IT1148812B (it) 1986-12-03
JPS55153776A (en) 1980-11-29

Similar Documents

Publication Publication Date Title
DE1593907C2 (de) alpha eckige Klammer auf 4-(p-subst.Phenyl>phenoxy eckige Klammer zu -carbonsäuren, deren Derivate sowie diese Verbindungen enthaltende Arzneimittel
DE2549783C3 (de) Triglyceride mit entzündungshemmender Wirkung
DE2929777A1 (de) N-alkylimidazolderivate, verfahren zu ihrer herstellung und solche enthaltende arzneimittel
DE68910211T2 (de) Estramustin-ester.
DE2723051C3 (de) NKAcyO-p-amino-NMn-decyl- und n-tridecyl)-benzamide sowie diese enthaltende Arzneimittel
DE3013502C2 (de) [2''-(Trifluormethyl)-phenthiazin-10''-yl-(n-prop-3'''ylpiperazin-4''''-yläth-2'''''-yl)]-ester, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel
DE2157272C3 (de) Verwendung von bis-(p-Chlorphenoxy)acetylharnstoff
DE3326724A1 (de) In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
EP0152868A2 (de) Isoxazol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2632118A1 (de) Apovincaminolester und verfahren zu deren herstellung
DE2137538C3 (de) oxyamin und seine Salze sowie ein Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
DE3026924A1 (de) 1,3-diphenoxypropan-2-ol-derivate sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2736268A1 (de) Neue 5-thiazolalkylamin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE1493513C3 (de) Sulfamylanthranilsäuren, deren therapeutisch verwendbare Salze, Verfahren zu ihrer Herstellung und diese enthaltenden pharmazeutischen Präparate
DE2410201B2 (de) 6-substituierte 3-carbaethoxyhydrazinopyridazine beziehungsweise ihre salze sowie solche enthaltende arzneimittel und verfahren zur herstellung derselben
DE1801312A1 (de) Verfahren zur Herstellung einer neuen Aryloxyalkansaeure und ihrer Salze
DE3028776A1 (de) Neue 1,3-diphenoxypropan-2-on-derivate sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel
WO1979000116A1 (en) New glycol compounds for lowering the lipid content
DE1801312C (de) 2 (4 Biphenylyloxy)-heptansaure, ihre Alkali und Erdalkahsalze und diese Verbin düngen enthaltene Arzneimittel
DE2022790C3 (de) 10-Methyl-5-[ (4-Methylpiperazino)-acetyl J-5,10dihydro-llH-dibenzo [b,e ] [1,4 ] diazepin-11-on, ein Verfahren zu dessen Herstellung sowie dieses enthaltende Arzneimittel
DE1543639C3 (de) Verfahren zur Herstellung von substituierten Phenylessigsäure!! und deren Salzen sowie genannte Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE2536387A1 (de) Pyrido(3,2-e)-as-triazinderivate, solche enthaltende arzneimittel sowie verfahren zur herstellung derselben
DE2125113C3 (de) Bis-(4-chlorphenoxy)-essigsäure-(Nmethyl-pyrrolidyl-2)-methylester und dessen Säureanlagerungssalze, Verfahren zu seiner Herstellung sowie diesen enthaltende Arzneimittel
DE1643460C (de) (3-Trifluormethylphenoxy)-(4-chlorphenyl)-essigsäureester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2145686C3 (de) 2-Chlor-S-sulfamylbenzoesäurederivate, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten

Legal Events

Date Code Title Description
OI Miscellaneous see part 1
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee